Mallet David

Postdoctoral researcher at the @EPFL, @Brainmind_EPFL 🧠, Sandi Lab - Laboratory of Behavioral Genetics 🇨🇭

[Mallet David @MalletDavid9]

It is finally here! Very proud to share my first paper in #JCI focused on a cross-species translational approach for the development of a metabolic biomarker for the early stages of Parkinson's disease #parkinson #metabolomics

[Journal of Clinical Investigation @jclinicalinvest]

#ClinicalMedicine: A metabolic biomarker predicts Parkinson’s disease at the early stages in patients and animal models: https://t.co/5JYjR9zTN9
@GINeuroGrenoble @Inserm
#Metabolism #Neuroscience

[Carmen Sandi @carmensandi10]

New lab paper! We reveal a novel mitochondria–cilia interaction in neurons & show #mitochondrial control of #ciliary molecular pathways & structure

Kudos to D Ulgen & @Ale_Chioino
🙏 @oliviazanoletti @albert_qr78 & E Sanz
@Brainmind_EPFL @NeuroLeman
Read https://t.co/8EQE8HlQvv

[Aurélie Lattion (-Papilloud) @pap_aure]

J'aimerais aujourd'hui partager un projet sur lequel je travaille avec @neuracademia: le tome 2 de la @maison_cerveau
Nos ouvrages vulgarisent les #neuroscience pour les enfants (et les plus grands) afin d'améliorer leur #SanteMentale
Pour les infos: https://t.co/zgySCjnIGK
RT!

[allen institute @AllenInstitute]

The first cellular map of a mammalian brain is here. 🧠✨

Over 6 years and 32 million cells in the making, the complete adult mouse brain cell-type atlas reveals astonishing diversity and regional specificity.

Dive deeper: https://t.co/CXEIXooOVu

@nature #studyBRAIN #BICCN

[Ewelina Knapska @e_knapska]

The paper is finally out! Congratulations to Anna Kaźmierowska, Mateusz Kostecki (@matkstecki), and Michał Szczepanik. Thank you, Artur Marchewka, Marek Wypych, and Jarosław Michałowski for the excellent collaboration (@Lobi_Nencki): https://t.co/N7GoDv7FZ3

[Carmen Sandi @carmensandi10]

Did you ever wonder "Why we don't all develop posttraumatic stress disorder"?
See key insights in our last paper led by @MonariSilvia & S Astori & collaboration with @brain_kcl
https://t.co/yGDJ0YdbCt @BiologicalPsyc1
& press release @epflSV @EPFL_en https://t.co/wlQrvE3yDV #epfl

[Carmen Sandi @carmensandi10]

Just out from the lab! New read!
We show that mitochondrial mitofusin 2 in nucleus accumbens D2, but not D1, medium spiny neurons regulates social dominance & mito & neuronal phenotypes!
Congrats to @SriparnaGhosal S_Astori &all the team!
https://t.co/SbvcGYNvMP
@Brainmind_EPFL

[Carmen Sandi @carmensandi10]

A review from the lab from two great postdocs Dogukan Ulgen and Silvie Ruigrok is out and available through the link below.
Powering the social brain: Mitochondria in social behaviour https://t.co/biAagCFvzM
@Brainmind_EPFL @NeuroLeman @StressnetworkC

[The Science of Parkinson's @ScienceofPD]

Excessive daytime sleepiness in a nonhuman primate model of #Parkinsons was improved by low-frequency stimulation of the pedunculopontine nucleus
https://t.co/pSKpo3nXCy

[Raphaël Goutaudier @GoutaudierRaph1]

It was a preprint, now it is accepted !! Thrilled to share the large body of works I did during my PhD, published in @molpsychiatry !

Hypodopaminergic state of the nigrostriatal pathway drives compulsive alcohol use. https://t.co/XIlHgutNO6

#addiction #dopamine #compulsivity

[Raphaël Goutaudier @GoutaudierRaph1]

Interested in addiction-related behavior ? Dopamine ? DREADDs ?
Carnicella's lab, at the Grenoble Institut Neurosciences, is looking for a #postdoc or a #phdstudent !

[Mallet David @MalletDavid9]

Thrilled to share this new paper on the modulation of energetic metabolism induced by MPC inhibition as a neuroprotective strategy. @SpringerNature #mitochondria #mpc #parkinson

[Mallet David @MalletDavid9]

Another fantastic work from @Meaghan_Creed lab by @YVachez

[Mallet David @MalletDavid9]

I am thrilled to present a poster at #fens2022 on Brain mitochondrial reprogramming as a biomarker and therapeutic target
Date & Time: 12th July 14.00-17.30
Poster session 6, board number S06-342

[Mallet David @MalletDavid9]

Back in business 🧬🧬 #metabolomic

[Mallet David @MalletDavid9]

🎥 French TV appearance on the occasion of the #WorldParkinsonsDay
@f3Alpes gave us the opportunity to talk to the general public about our research on an early blood biomarker for the diagnosis of Parkinson's disease.
https://t.co/1T3c6JUV1n

#ParkinsonsDisease

[Neuroimagerie Grenoble Institut Neurosciences @nifm_gin]

Hier matin, @AMorelch sur @franceinter a consacré un sujet aux travaux de @MalletDavid9, F. Fauvelle et S. Boulet sur la découverte d'un biomarqueur métabolique capable de détecter de manière précoce la maladie de #Parkinson. Replay disponible à 9min35: https://t.co/2K2xqKZRbb

[Place Gre'net @placegrenet]

Des chercheurs grenoblois pensent pouvoir détecter précocement la maladie de Parkinson avec une prise de sang - https://t.co/0fLeVwUQ62

[Journal of Clinical Investigation @jclinicalinvest]

#ClinicalMedicine: A metabolic biomarker predicts Parkinson’s disease at the early stages in patients and animal models: https://t.co/5JYjR9zTN9
@GINeuroGrenoble @Inserm
#Metabolism #Neuroscience

[The Science of Parkinson's @ScienceofPD]

New @biorxivpreprint manuscript finds mitochondrial pyruvate carrier inhibitor MSDC-0160 can attenuate neurodegeneration in a rodent (6OHDA) model of #Parkinsons;⬇️ mTOR activity & neuroinflammation, plus⬆️ketogenesis, beta oxidation & glutamate oxidation
https://t.co/d9s4zdklqO