Mandy van Leent

Assistant Professor @BMEIIsinai | Icahn School of Medicine at Mount Sinai 🏥 |
Molecular Imaging & Cardiovascular Disease 🔬

[Fil Swirski @SwirskiLab]

Influenza hijacks myeloid cells to inflict type-I interferon-fueled damage in the heart: Immunity https://t.co/OTdGq4MJ7y

[Mandy van Leent @mandyvanleent]

Bram and I have been thinking a lot about how PET imaging might shed light on trained immunity mechanisms in CVD🫀. We summarized our ideas in a brief review, now published in ATVB. Curious what you think! ✨

https://t.co/qO3hM2KkGT

@BMEIIsinai @SinaiHeartBlood

[Mandy van Leent @mandyvanleent]

What's better than winning an award yourself? Seeing our student shine! Congrats to Kymani Lewis for taking home 1st prize 🏆 at the BMEII Volunteer Research Day! I'm very proud 😊 @BMEIIsinai @zahifayad

[David Sancho @SanchoLab]

💥 A gut microbe metabolite that drives #atherosclerosis?
Yes—Imidazole propionate (ImP) triggers vascular inflammation without changing cholesterol.
🧪 We show the pathway—and how to block it.
https://t.co/ZazBw50FFC #OpenAccess at
@Nature
@CNIC_CARDIO
#microbiome #CVD

[Mandy van Leent @mandyvanleent]

Here's a happy summer picture of our team for you! Taken after a hard day's work 🔬 and well deserved ice cream 🍦

[Cameron McAlpine @cam_phd]

We are delighted to share our latest findings today in @Nature. We describe cardiogenic regulation of sleep after cardiac injury.

“Myocardial infarction augments sleep to limit cardiac inflammation and damage”

https://t.co/ip6psmJBZ2

[Roy van der Meel @rvdmnanomeds]

🔥 New study on #polymersomes for #immunotherapy just out in @NatureNano! Great effort by @WillemNANO at @radboudumc, @AbdelmohsenLab & @vanhest_lab at @TUeindhoven, @mandyvanleent & Bram Teunissen @BMEIIsinai and @AviSchroeder at @TechnionLive!

https://t.co/js5htdVFRW

[Charbel Gharios @CharbelGharios6]

In this paper on stress & CVD, we find a novel association between disruptions in the uncinate fasciculus and carotid atherosclerotic burden.

Grateful to @ATawakolMD @zahifayad for this opportunity and to @daveoctweets @mandyvanleent for all the help!

https://t.co/mU23042JUE

[Mandy van Leent @mandyvanleent]

Yay! Excited to see this study - led by Carlos Pérez-Medina and Bram Teunissen - out in the world! @BMEIIsinai @SinaiHeartBlood

[Tim Witney @TimWitney]

📢New paper published in #npjImaging @Nature_NPJ 'Macrophage PET imaging in mouse models of cardiovascular disease and cancer with an apolipoprotein-inspired radiotracer' from @mandyvanleent and colleagues @IcahnMountSinai @CNIC_CARDIO

Open access and free to read below👇

[Mandy van Leent @mandyvanleent]

@HeartInstitute @KateyRayner Congrats Katey!!

[Mandy van Leent @mandyvanleent]

Read our new review paper in @NatRevCardiol on PET imaging 🔍of cardiovascular disease!

We talk about fascinating technological developments and discuss recent results from clinical trials 🏨

[BioMedical Engineering and Imaging Institute @BMEIIsinai]

Now online! BMEII investigators review the latest developments in the world of atherosclerosis PET imaging in Nature Reviews Cardiology. Click here for full access to the article: https://t.co/Ik1LGFfNWi @mandyvanleent @zahifayad @alexm_official

[Alexander Maier @alexm_lab]

💥your new favorite imaging review🔭: “Uncovering Atherosclerotic Cardiovascular Disease by PET imaging“ @NatRevCardiol 💜
https://t.co/LfoPT0eZyv

👨🏻‍🔬👩🏼‍🔬@mandyvanleent @LutgensEsther @zahifayad 🏥@BMEIIsinai @UHZ_UNIFreiburg

[Mandy van Leent @mandyvanleent]

Great presentations by Trea, Anna and Sheqouia in the poster session at #BMEII2024!

[Wolfram Poller @WolframPoller]

Interested in studying how the brain controls our cardiovascular health? Come and join our growing lab at MGH and HMS as a PostDoc. Expect full support, scientific freedom, and a very friendly environment. Check here for details https://t.co/UISA89jXVW Please RT!

[Mandy van Leent @mandyvanleent]

Thanks Roy! Good to see you!

[Roy van der Meel @rvdmnanomeds]

Outstanding talk by @BMEIIsinai @mandyvanleent on imaging host response in inflammation at @ESMI_society #EMIM2024

[zahifayad @zahifayad]

Happy holidays from @BMEIIsinai Here to a great end to 2023 and we welcome 2024 with feelings of gratitude, optimism and strength #notafraid

[Mandy van Leent @mandyvanleent]

Happy holidays from the best team! 💪🏼👩🏽‍🔬👨🏻‍💻💜 @BMEIIsinai

[Mandy van Leent @mandyvanleent]

@WillemNANO Gefeliciteerd Willem!! Dat is geweldig 🤩💪🏼🎉

[Mandy van Leent @mandyvanleent]

I've been waiting to see these CCR2 PET images of patients with myocardial infarction. Looks really promising! 👏

[Nature Cardiovascular Research @NatureCVR]

RESEARCH| Lavine et al. establish the feasibility of C-C chemokine receptor 2 (#CCR2) #imaging, a marker of inflammatory monocytes/macrophages, in patients that suffered a #MyocardialInfarction| @LavineLab, Yongjian Liu, @WUSTL https://t.co/wt0EcoylUm

👉https://t.co/M3bd7C36dk

[BioMedical Engineering and Imaging Institute @BMEIIsinai]

We could not be more excited to kick off the next five years of studying the connections between stress & cardiovascular health with the best team! @nih_nhlbi
https://t.co/iZ3dFV23PD