Manisha Gupta 🇮🇳

[Ananth Rupanagudi @AnanthOnTrack]

An Indian scientist at Harvard discovered ATP (Adenosine Triphosphate). Then he helped create the first chemotherapy drug and the first tetracycline antibiotic. Harvard still refused him tenure. A bowling alley would not let him bowl. He died at 53, without an obituary.

His medicines save tens of millions of lives every year. Most American doctors who prescribe them have no idea what his name was. His name was Yellapragada Subbarow (Subba Rao).

He was born in 1895 in Bhimavaram, India. His father was a Sanskrit scholar who died from tropical sprue. Tropical sprue is an acquired malabsorptive disorder found in tropical regions, characterized by chronic diarrhea, weight loss, and severe nutritional deficiencies. It is most commonly associated with deficiencies in vitamin B12 and folic acid, resulting in anemia, fatigue, and glossitis. The same disease killed two of his brothers. As a child, Subbarow watched them fade away and decided he would spend his life fighting disease.

He failed his school exams twice. Passed on the third attempt. His future father-in-law paid for his medical school books. Subbarow married his daughter and repaid the debt. In October 1922, he arrived in Boston with borrowed money and broken English. He was 27. He entered Harvard Medical School and joined the biochemistry PhD program.

He began working under a senior researcher named Cyrus Fiske. Long hours. Little pay. But he was at Harvard, and he did not care. In 1925, they developed the Fiske-SubbaRow assay, a method for measuring phosphorus in body fluids. It is still used today in kidney failure testing, vitamin D testing, and prostate cancer work. It became one of the most cited methods in biochemistry history.

Then they found something even bigger in 1926 - ATP - Adenosine triphosphate. The energy molecule that powers every cell in every living thing on Earth. That discovery changed biochemistry. It also proved that the 1922 Nobel laureate had been wrong about how muscles worked. Muscles did not run on glycogen. They ran on ATP.

Subbarow earned his PhD in 1930. He stayed at Harvard for another decade. Paper after paper. Discovery after discovery. And every year, Harvard refused to promote him. The biochemistry department had never given tenure to a foreigner. They were not going to begin with an Indian.

His colleagues took him fishing. Played tennis with him. Came to dinner at his home. Then voted against him year after year. Outside the laboratory, he met the same wall. He bought an airplane and learned to fly because he loved flying. Once, he tried to go bowling. The local alley refused him entry. The sign said it was “open only to the Caucasian race.”

Then Fiske turned against him. The senior researcher began blocking Subbarow’s discoveries out of jealousy. Some of Subbarow’s work had to be rediscovered years later by other scientists because Fiske kept his findings hidden.

May 1940. Harvard denied him tenure for the last time. After 17 years of groundbreaking work, he walked away. Lederle Laboratories in New York hired him as Associate Director of Research. By the end of the year, he was Director. In the next eight years, he changed medicine. He developed diethylcarbamazine, an oral medicine that killed the tropical worms crippling American soldiers in the Pacific. The World Health Organization still uses it.

He isolated folic acid from liver and worked out how to produce it on a large scale. Today, folic acid in pregnancy prevents birth defects in tens of millions of pregnancies every year. The same family of diseases that killed his father and brothers became preventable because of him.

Then Dr. Sidney Farber called from Boston with an idea: maybe a drug that blocked folic acid in cancer cells could kill childhood leukemia. Subbarow’s team created the drug. They called it Aminopterin. In December 1947, Farber gave it to an eight-year-old boy dying from leukemia. Within weeks, the cancer cells began to disappear.

It was the first chemotherapy drug in history. The first time anyone had put cancer into remission using a pill. Subbarow’s team later refined it into Amethopterin, now known as methotrexate. It became a gold standard treatment for leukemia, lymphoma, breast cancer, and lung cancer. Then rheumatoid arthritis, psoriasis, and Crohn’s disease. The World Health Organization lists it as an essential medicine. Tens of millions of people use it every year.

In 1948, his lab produced Aureomycin. The first tetracycline antibiotic - a broad-spectrum one that killed typhus, cholera, pneumonia, and many bacteria that penicillin could not touch. It opened the door to the whole tetracycline family: doxycycline, minocycline, and drugs still used today against plague, malaria, anthrax, and drug-resistant infections.

He was 53 years old. He had created medicines that would save tens of millions of lives. August 8, 1948. Yellapragada Subbarow suffered a heart attack at his home in New York and died. No American newspaper gave him a front-page obituary. No university held a memorial. The Nobel Committee never honoured him. His own colleague George Hitchings later won a 1988 Nobel Prize for work built directly on Subbarow’s foundation. Subbarow was not even nominated.

In 1950, Argosy magazine published a feature about him titled “Miracle Man of the Miracle Drugs.” It began with a line that still hits hard. “You’ve probably never heard of Dr. Yellapragada Subbarow. Yet because he lived, you may be alive and are well today. Because he lived, you may live longer.”

Most Americans had not heard of him in 1950. Most still have not. Harvard has never officially honoured him. American medical schools mostly do not teach his name. The Nobel Committee that honoured Hitchings for work built on his foundation never corrected the record. Every methotrexate prescription written today remains silent about the man behind it.

India remembers. The government issued a postage stamp for his 100th birthday. His childhood home became a museum. Indian medical schools teach his name. But the country that denied him tenure, refused to let him bowl, and allowed him to die unknown - the same country that uses his drugs every day - still mostly does not know him.

Here is the truth. If someone you know has ever taken methotrexate for cancer or an autoimmune disease. If someone you love has taken folic acid during pregnancy. If you have ever been prescribed doxycycline for an infection. That was him. Yellapragada Subbarow. Born 1895. Died 1948. Saved tens of millions of lives, while a country he loved barely knows what it owes him.

Please remember his name and let your near and dear know about this little-known scientific legend born on this soil but never got the true recognition that he deserved. A story you need to know. A story all of us need to know. #Medicine #Unknownlegends @centerofright @KiranKS

[Indrajit @Lotus_indrajit]

Singapore’s former Prime Minister, Lee Kuan Yew, once said:

“Missionaries did their best to convert India and China to Christianity, but their plan failed, they managed to convert only a very small number of people.”

Make sure you listen to the last two lines he spoke…

[Aditya Dhar @AdityaDharFilms]

You might have seen numerous videos of Kashmiri Pandits breaking down in the theatres after watching #TheKashmirFiles. The emotion is real. It shows how long we kept our pain and tragedy repressed as a community. We didn’t have any shoulder to cry on and no ear to hear our pleas.

[Ananth Rupanagudi @AnanthOnTrack]

Some were asking why Sankranti is on 15th January this year and not 14th. I found this useful scientific explanation.

Makara Sankranti for the next 69 years will fall on 15th January, not 14th. It is simply a function of precession of equinoxes.

Also, it is important to understand that Ayana is understood from the tropical position of the Sun, not Sidereal. So, Sankranti is no longer co-terminus with Uttarayan. The reason is the same - precession of Earth.

From the next century (every 72 years approximately), Makara Sankranti would be on 16th January!

Remember - During the third battle of Panipat, Sankranti was on the 10th, as the war was happening on that tithi. Also, Swami Vivekananda was born on 12-Jan-1863 and it was Sankranti on that day.

Every year, the time taken by Sun to enter makara rashi shifts by 20 minutes. So it takes 72 years (24x60/20) to shift by one full day. You can check Sankranti date over the years...it matches.

It's perfect mathematics.

HAPPY SANKARANTI, EVERYONE! #MakaraSankranti #HappyMakarSankranti #Sankranti2026 #mathematics

[CA Akhil Pachori @akhilpachori]

#IndiGo logic:

New DGCA rule gives pilots 12 extra hours rest per week which caused sudden pilot shortage leading to 1000+ cancellations

60% market share giant can’t hire 200 more pilots in 18 months of notice?

Air India → normal operations
Akasa → normal
Vistara → normal

This has caused Airports in chaos

DGCA gave 6-18 months transition period.

Air India hired 500+ pilots in advance.

IndiGo hired almost none and kept expanding routes

#Indigoairlines #IndigoDelay #indigochaos

[Comman Man @CommanMan777589]

They tried to Erase us through shame, but we ROSE through pride…

One of the best video I have seen in recent times!

You cannot stop the unstoppable.

Do invest your 4 minutes and share to as many people as you can…

Jai Sri Ram

[P.N.Rai @PNRai1]

शुभ दीपावली लिखी यह सरकारी बस भारत या नेपाल में नहीं चल रही है।

यह दृश्य न्यूजीलैंड की राजधानी ऑकलैंड का है। यह बस दीपावली नजदीक है, का संदेश दे रही है।

भारत के किसी सरकारी बस पर लिखा मिल जाए तो संविधान खतरे में पड़ जाएगा। सरकार कम्युनल घोषित कर दी जाएगी।

भारत में तो दिवाली पर पटाखा जलाने की भी आज्ञा मिलर्ड से लेनी पड़ती है।

[Manpreet Singh Dhami @5karma_films]

The release of #HisStoryOfItihaas is a journey of a fight for screens, of the claps, emotions, revelations & people support.
Running In cinemas far from you !
(Plz repost & bookmark for sending a msg to the mafia ecosystem)
@AtriNeeraj
@Aabhas24
@JaipurDialogues @GemsOfBollywood

[Ministry of Defence, Government of India @SpokespersonMoD]

All media channels, digital platforms and individuals are advised to refrain from live coverage or real-time reporting of defence operations and movement of security forces. Disclosure of such sensitive or source-based information may jeopardize operational effectiveness and endanger lives. Past incidents like the #KargilWar, 26/11 attacks, and the #Kandahar hijacking underscore the risks of premature reporting. As per clause 6(1)(p) of the Cable Television Networks (Amendment) Rules, 2021, only periodic briefings by designated officials are permitted during anti-terror operations. All stakeholders are urged to exercise vigilance, sensitivity, and responsibility in coverage, upholding the highest standards in the service of the nation. 🇮🇳

Read more: https://t.co/bHscgUBMEV

#MediaAdvisory #NationalSecurity #MIBIndia #ResponsibleReporting

@rajnathsingh
@DefenceMinIndia
@SethSanjayMP
@HQ_IDS_India
@adgpi
@indiannavy
@IAF_MCC
@PIB_India

[Manisha Gupta 🇮🇳 @manishagupta89]

@ANI Triveni Sangam devoid of its devotees today!

[Manisha Gupta 🇮🇳 @manishagupta89]

@ANI Not fair!! Due to VIP visit no one has been able to perform Amrut snan at the Sangam since morning.

[Manisha Gupta 🇮🇳 @manishagupta89]

Mahakumbh going on AND the sangam is empty! Devoid of the devotees!

[Manisha Gupta 🇮🇳 @manishagupta89]

Arrived at Prayagraj early morning to have Amrut snan at Triveni Sangam.. unfortunately it has been closed since morning for a VIP visit.. how fair is that when people have taken pains & come with a plan just for a day? @narendramodi @myogiadityanath @AmitShah

[Manisha Gupta 🇮🇳 @manishagupta89]

Also tomorrow being Sunday won’t this lead to added crowd .. & increase hardships for common man? Or do we need another stampede like situation .. people have nowhere to go, no place to stay, harsh weather, absurd security protocols for crowd management.. It’s simply ridiculous!

[Stringg @StringReveals]

BREAKING🚨 The bubble of US indictment finally bursts. The Leftist lobby & wannabe activists were after Adani to tarnish his reputation without any evidence.

Former Attorney General Mukul Rohatgi reveals shocking details. #WatchVideo

- Remember how Deep state bombarded Trump with 100s of crimes, but now all cases have collapsed

- Deep State even destabilized Indian borders via regime change & imposition of Muhammad Yunus in Bangladesh

- Don't forget Indian LOP - another puppet of Soros, outrageously demanded over this Adani's arrest without examining facts.

Paste in comments: #AdaniNotGuilty

[The Jaipur Dialogues @JaipurDialogues]

Sambhal is the land of Kalki Avatar!

Wake up Hindus, Reclaim your land!

#SambhalMosqueRow

[CoHNA (Coalition of Hindus of North America) @CoHNAOfficial]

BREAKING 🚨🚨: A new study from @ncri_io and the Social Perception Lab at Rutgers confirms what we have suspected all along: hateful rhetoric on #caste from #Hinduphobic groups like #EqualityLabs causes average Americans to view ALL #Hindus with increased suspicion and bias.

Remember the infamous “Caste discrimination in the US” ‘survey’ from #EqualityLabs which has been the basis for or so many anti-Hindu policies in universities, cities and corporations across the US? And #SB403 @SeattleCouncil @aishabbwahab @UCD_Diversity @CFA_United

NCRI's report finds Equality Labs’ ‘anti-caste’ narrative from this ‘survey’ creates significant harmful bias against #Hindus in general & against perceived ‘upper castes’ in particular. It is a devastating validation of what recent institutional actions + our own lived experience has shown.

Study participants exposed to the Equality Labs narrative, were more likely to view ALL Hindus as racist, more likely to perceive bias without any evidence of bias and alarmingly, more willing to punish perceived ‘oppressors’

In a particularly shocking finding, after reading the Equality Labs content, participants were MUCH MORE LIKELY to literally AGREE with Hitler’s quotes (with the word ‘Brahmin’ replacing ‘Jew’). 🚨

They agreed that #Brahmins are “PARASITES” (+35.4%), “VIRUSES”(+33.8%), and “the DEVIL PERSONIFIED” (+27.1%). 🚨

In the now collapsed, but still infamous @Cisco caste lawsuit, California CRD @calcivilrights forcibly described the defendants as #Brahmin – violating Sundar Iyer’s self-professed identity as an #agnostic.
https://t.co/iezltiJ5K3

It was likely the outcome of the way Equality Labs describes #Brahminism in their training on Caste. Hear their founder in her own words (hat tip: @hinduoncampus)
https://t.co/mgt1i1uwo2

We shudder to think of the consequences for #AmericanHindus had #California's SB 403 been signed into law and Equality Labs given the opportunity to ‘educate’ people on #caste. But despite the #SB403 veto (thanks @GavinNewsom ) we know the caste training bandwagon rolls on.

Time for the #DEI leaders to take a serious look at the deep harm they are inflicting on a small minority community.

@CASenateDems @AssemblyDems @aishabbwahab @CA_Dem @TheDemocrats @DNC
@CA_Dem @CAGovOps @CAGOP @AsmRepublicans @alamedacounty @napaba

@BillAckman @VivekGRamaswamy @thebritishhindu

[🇺🇸Steve2A🇺🇸God🇺🇸Family🇺🇸Country🇺🇸 @lakemonstercl1]

Is there anything Vivek can't do?

If Elon and Vivek succeed in cleaning up government waste, I think he may have a legitimate chance to become a future president!

[Madhu Pandit Dasa @madhupanditdasa]

We have come across disturbing reports that Sri Chinmoy Krishna Das, one of the prominent leaders of ISKCON Bangladesh, has been detained by the Dhaka police. We are deeply concerned about the situation and expect the Government of Bangladesh to ensure the safety of Chinmoy Krishna Das, ISKCON devotees and all other persecuted minority communities.

It is outrageous to make baseless allegations that ISKCON has anything to do with terrorism anywhere in the world. ISKCON urges the Government of India to take immediate steps and speak to the Government of Bangladesh and convey that we are a peace-loving Bhakti movement. ISKCON Bangladesh has been engaged in various humanitarian services for beneficiaries, irrespective of religion or any other considerations. ISKCON’s constant efforts to support people through the Food Relief programme during floods in Bangladesh are well known.

Our sympathies are with the dedicated devotees of ISKCON Bangladesh, and we want the Government of Bangladesh to release Chinmoy Krishna Das immediately. Our prayers to Lord Krishna for the protection of these devotees.

@narendramodi @DrSJaishankar @MEAIndia @ihcdhaka @BDMOFA

#FreeChinmoyKrishnaPrabhu
#SaveBangladeshiHindus

https://t.co/OoBE89K0Hr

[Elon Musk @elonmusk]

India counted 640 million votes in 1 day.

California is still counting votes 🤦‍♂️