What if doctors could use your own tumor to teach your immune system to destroy cancer? UCSF scientists may have found a way. By coating lab-grown immune cells with pieces of a patient’s own tumor, they trained T cells to recognize and attack the cancer. https://t.co/3HSJgWtF2V
A highlight from last week: Can routine archived clinical biopsies help predict treatment response in ulcerative colitis? https://t.co/GUF0MepRnF
@MikeKattahMD, @alexis_combes & team @UCSFMedicine applied spatial gene mapping to archived colitis biopsies, identifying immune cell neighborhoods that explain why some patients are resistant to vedolizumab and others respond well.
@MayoClinic
#Colitis #IBD
📢 PhD position open at #VHIO 🧑🔬
Join the Cell Engineering and Hematologic Immunotherapy Group, led by Pere Barba, and work on:
🧬 Cellular immunotherapy
🩸 CAR T-cell biology
🔬 Genomics
🎯 Translational cancer research
🗓️ Deadline: 26/06
Apply 👇
https://t.co/IrIHRUvGDj
Intratumoral CD4+CD8+ T cells can serve as precursors to single positive T cells in vivo via Rag2 expression, suggesting that tumors act as extrathymic sites of T cell development @UCSF
https://t.co/9GKYUKkcFa
Not only does UCSF's NIH-funded research advance health care and improve patients' lives, it has an estimated $18.7B ripple effect on the economy. The result is more innovative startups, more jobs, and stronger companies that hire workers nationwide. https://t.co/zi7zp0LFlG
La Vanguardia entrevista la investigadora de l'#IDIBAPS@GuedanS, finalista dels premis La Vanguardia de la ciencia.
La pots votar en aquest enllaç 👉https://t.co/nXLy7Uakti
🗞️Sònia Guedán (@GuedanS), cap de grup de l'#IDIBAPS, entre les 8️⃣ finalistes al premi Vanguardia de la Ciència
Una iniciativa de @LaVanguardia i la @FCLP_Fundacio per visibilitzar dones científiques i reduir la bretxa de gènere en la recerca
👉https://t.co/kd9eMuwSbn
🔬Our latest study from the Ashkenazi lab at @genentech reveals a previously unrecognized mechanism of IRE1 signaling. This discovery redefines current models and introduces a new framework for therapeutic targeting in cancer. 📖 Read more: https://t.co/xUWe7C1hDf
Tumor localized CTLA4 blockade using a cleavable, conditionally activatable DVD IgG provides primary antigen-specific anti tumor efficacy in localized and systemic preclinical tumor models! Thanks as always to
@MarcelArias@lawfong for the mentorship!
https://t.co/3XW7WuCSUk
New #JITC article: Impact of tumor localization on antitumor immunity with conditionally activated CTLA-4 blockade https://t.co/g8SXyVr5p9 @MarcelArias@UCSF
Think global, act local! Just like the fully cleavable, conditionally activatable DVD CTLA4 blockade we report at https://t.co/WYYJAWXGP0 ! It provided safe, primary antigen-specific antitumor efficacy in localized and systemic preclinical tumor models. @lawfong
🎭 This Friday, March 28, our #UCSF#improv group is hitting the stage at @TheLostChurchSF!
A bunch of #scientists doing improv—what could go wrong? (Or very right 😄)
Expect laughs, chaos, and a great show!
🎟️ Grab your tickets here:
https://t.co/0qQeEmRDev
Me hace mucha ilusión haber recibido el reconocimiento al mejor artículo científico de 2024 junto a @GuedanS y @fara_bm durante el segundo #EncuentroInvestigadoresAECC. Fue una jornada increíble rodeada de colegas y amigos. Muchas gracias @contracancerINV por vuestro apoyo! 💚
In this fantastic collaboration with Abbvie we were able to find time-sensitive synergistic effects between immune checkpoint blockade and JAK1 inhibition in boosting T cell fitness against tumors in mice. Online today! https://t.co/T0EbhEuAtw @lawfong
Aram Lyu, Peiqi Ou, Helen Rizos, and Annette Paschen discuss "Cancer Immune Evasion" in a symposium at the AACR IO Conference on Discovery and Innovation in Cancer Immunology. #AACRIO25@HelenRizos@AramLyu