marcelo nollmann

Physicist, geneticist, programmer, or anything in between. Interested in how the genome is organized and moved around by motors.

[marcelo nollmann @marcelonollmann]

Congratulations @juliangurgo for his pre-print on the organization of Pc domains during development, an exciting collaboration with Frédéric Bantignies, @WalterJeanChar1 and @giacomo_cavalli. See https://t.co/l4OHG7Vn2Y

[marcelo nollmann @marcelonollmann]

A tour de force study from Olivier Messina and coauthors where he used multiplexed DNA imaging to discover common folding motifs in chromatin, a finding that will open many future perspectives.

[Messina Olivier @MessinaOlivier1]

📢 We are thrilled to announce our new manuscript out on BioRxiv:

"Chromatin folding motifs define the basic grammar of TAD architecture in single alleles" 🔬🧬

Read the full paper on bioRxiv:

🔗 https://t.co/Bx310StVqY 🔗

Check out our key findings below! 👇

[Messina Olivier @MessinaOlivier1]

📢 We are thrilled to announce our new manuscript out on BioRxiv:

"Chromatin folding motifs define the basic grammar of TAD architecture in single alleles" 🔬🧬

Read the full paper on bioRxiv:

🔗 https://t.co/Bx310StVqY 🔗

Check out our key findings below! 👇

[marcelo nollmann @marcelonollmann]

These results are consistent with long-range Pc interactions being temporally and spatially regulated during differentiation and development but do not seem to involve clustering of multiple distant Pc genes.

[marcelo nollmann @marcelonollmann]

Congratulations @juliangurgo for his pre-print on the organization of Pc domains during development, an exciting collaboration with Frédéric Bantignies, @WalterJeanChar1 and @giacomo_cavalli. See https://t.co/l4OHG7Vn2Y

[marcelo nollmann @marcelonollmann]

Also, 3D proximities are particularly enhanced in segments where Pc genes are co-repressed & segment-specific expression of Hox Pc targets leads to their spatial segregation from Pc repressed genes.

[marcelo nollmann @marcelonollmann]

@christlet @EmmanuelMargeat Thanks for the link to joplin! I have used a local instance of hedgeDoc but my worry is that notes are saved in a database... So we turned to Obsidian with files sync across devices using Nextcloud/Dropbox

[marcelo nollmann @marcelonollmann]

Been studying lately the best options for electronic lab books and finally turned to markdown-github after some study of the best options (https://t.co/bjPHJuX7oo). Anyone has advice?

[marcelo nollmann @marcelonollmann]

We conclude that the changes in chromatin structure of single nuclei are not determined by any single factor, but by multiple distributed parameters.

[marcelo nollmann @marcelonollmann]

We are happy to present our latest work on #3DGenome organization and #transcription #epigenetics during #drosophila #development, now available on @biorxivpreprint https://t.co/Rw3uvjxLPO Continue Reading for an overview @marcelonollmann

[marcelo nollmann @marcelonollmann]

Transcription within a TAD led to small changes in the 3D genome structures of single nuclei.

[Carmelo Ferrai @CarmeloFerrai]

beautiful!

[System76 @system76]

Our new key switch installation machine, real name Herman, is hard at work! Herman installs switches to free up time for our Production Team members to focus on other tasks.

#HowItsMadeMonday #keyboard #manufacturing #madeindenver #madeinusa #foss #launch #qmk

[Ralf Blossey @RalfBlossey]

Our latest paper concerns the role of pioneer transcription factors, which comes closest to our original concept. - Pioneer transcription factors in chromatin remodeling: The kinetic proofreading view
Helmut Schiessel and Ralf Blossey
Phys. Rev. E 101, 040401(R) (2020)

[Thomas Merritt @tjsmerritt]

Catch Fruit Flies!

Twitterverse - I need your help to make a dataset for a teaching lab

I need as many people as possible, from as many places as possible, to trap fruit flies.

Please retweet

We’re going to create one, global, dataset

#Drosophila #STEM #teaching