We concluded that higher levels of potassium channel activity in distal hippocampal axons serve to sustain AP fidelity, conveying a reliable digital signal to presynaptic boutons. 11/11
Our study of the action potential in hippocampal axons using some of the latest GEVIs is now available to read in @SfNJournals#JNeurosci: https://t.co/2G7af79TI3 @jbneuro@VicGSB 1/11
Distance-dependent differences in the short-term plasticity of the action potential were shown to be partly mediated by 4-ap-sensitive potassium channels. Application of 4-ap during action potential trains induced waveform widening that was more pronounced in distal axons. 10/11