Akash Hosamani

Bioinformatics PhD | Python
Working on computational genomics & CRISPR systems
Building tools to make sense of biological data

[Akash Hosamani @MatrixTrend]

This doesn’t “destroy” the Central Dogma (Crick himself never claimed it was absolute), but it beautifully expands it.
The more we look, the more we realize biology is far more flexible and creative than we imagined.
Is this the beginning of more exceptions to come?

[Akash Hosamani @MatrixTrend]

I've always had a quiet doubt about the Central Dogma. The idea that information only flows DNA → RNA → Protein felt too neat, too absolute. Deep down I thought - one day something will break this clean picture.
Today, that day feels closer. 👇👇
Paper: https://t.co/deCppaBtxh"

[Akash Hosamani @MatrixTrend]

A paper in Science just showed a bacterial reverse transcriptase (Drt3b) that synthesizes repeating DNA using the protein itself as the template - no RNA or DNA guide needed for one strand.
Specific amino acids in the enzyme directly dictate the AC repeat sequence.
Protein → DNA

[Akash Hosamani @MatrixTrend]

Once those layers of conditioning begin to fall, the next step is Jiddu Krishnamurthy.
He doesn’t give you beliefs - but he makes you see.
Through him, you start understanding the core of life, awareness, and the nature of the mind itself.

[Akash Hosamani @MatrixTrend]

Most people talk about enlightenment, but very few understand how it actually happens.
If you really want to understand real yogis, you need to unlearn first.
There’s a simple 2-step path most people miss 👇
#Osho #Krishnamurthy

[Akash Hosamani @MatrixTrend]

If you want to understand real yogis and how enlightenment happens, you have to go beyond surface-level ideas and start learning from the masters.
A powerful starting point is Osho - his talks directly challenge beliefs and strip away illusions using sharp, uncompromising truths

[Akash Hosamani @MatrixTrend]

@naval @naval Can you please share more about spirituality or whatever you call it like a state of mind? It's really interesting but I am still a beginner. Can you make a podcast on that or any thing like that so we can understand those things?

[Akash Hosamani @MatrixTrend]

@Mrcryptoxwhale Done

[Akash Hosamani @MatrixTrend]

@zachpogrob Banglore

[Andrew D. Huberman, Ph.D. @hubermanlab]

Just think how much we can each and all create for sake of good, if we deliberately transmute the impulse to gossip or engage in ineffectual criticism, into thoughts and actions that actually build something. Choice points to do this abound.

[Navalism @NavalismHQ]

"I just don’t believe in anything from my past. Anything. No memories. No regrets. No people. No trips. Nothing. A lot of our unhappiness comes from comparing things from the past to the present."

@naval

[Nassim Nicholas Taleb's Wisdom @TalebWisdom]

"The market is like a large movie theater with a small door. And the best way to detect a sucker is to see if his focus is on the size of the theater rather than that of the door." - Nassim Nicholas Taleb in Skin in the Game

[Abacus.AI @abacusai]

1.8 million scientific papers are published every year.

Keeping up is impossible.

Here is a solution:

Look at https://t.co/BSAvqP22h5. They use AI to summarize and explain things to you. Another amazing use of Large Language Models.

AI explaining AI!

[Harsh Makadia @MakadiaHarsh]

Hot AI Tools To Try Today!

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[Pratham @Prathkum]

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[Harsh Makadia @MakadiaHarsh]

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[Navalism @NavalismHQ]

"If you want to make the maximum amount of money possible, if you want to get rich over your life in a deterministically predictable way, stay on the bleeding edge of trends and study technology, design, and art—become really good at something."

@naval

[Naval @naval]

It takes time to develop your gut, but once it’s developed, don’t listen to anything else.

[Andrew White 🐦‍⬛ @andrewwhite01]

Made a tool to answer open-ended research questions with citations. Started this weekend and initial results are very interesting.

Example question 1: What therapeutics are available or being researched for ALS?
1/5

[Siddha Performance @KapilGuptaMD]

THE MYTH OF MINIMALISM

https://t.co/Qb7ceYFAr0