Matthew McCormack

[智东西China AI News @Chinazhidx]

🚨#Alibaba DAMO Academy × Westlake University develop ReproPerturb, an AI model for stem cell reprogramming



Predicts cell reprogramming recipes from 4M combinations

Generates hypoblast-like stem cells sustained 50+ passages

Now applied to Parkinson’s cell therapy research

[Yilong Zou Lab @ZouYilong]

We are thrilled to share our work for the development of iPEX, a spatial proteomics technology. In this method, we integrate chemical anchoring of proteins, isotropic tissue expansion, and mass spec imaging for protein mapping (https://t.co/2eXWoxY417) (https://t.co/pZZwzKmqe6).

[nature @Nature]

Nature research paper: iPEX enables micrometre-resolution deep spatial proteomics via tissue expansion

https://t.co/RK9JZr7x2d

[The Nobel Prize @NobelPrize]

Mary Brunkow and Fred Ramsdell – who have been awarded the 2025 Nobel Prize in Physiology or Medicine – gained decisive insights into how autoimmune diseases arise.

Brunkow and Ramsdell made a key discovery in 2001, when they presented the explanation for why a specific mouse strain (named scurfy) was particularly vulnerable to autoimmune diseases.

The medicine laureates had discovered that the mice have a mutation in a gene that they named Foxp3. They also showed that mutations in the human equivalent of this gene cause a serious autoimmune disease, IPEX.

The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

[Samantha Morris @morris_lab]

Saddened to hear of John Gurdon’s passing. A brilliant scientist, generous mentor, and endlessly curious. When he examined my PhD viva in 2006, he’d just come from doing experiments at his bench - at 73. He shaped so many careers, including mine: https://t.co/p0OrXZv4Yy

[nature @Nature]

BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance"

Stay tuned for more.
#NobelPrize

[EMBL Australia @EMBLAustralia]

👋 Meet our new Scientific Head — Professor Jose Polo!

A world leader in epigenetics & stem cell biology, Prof Polo (@SAiGENCI, @UniofAdelaide, @Monash_FMNHS) brings his expertise & passion for advancing life sciences in Aus & beyond. 🌏

https://t.co/0J1WyojkdG

[BioInformant @StemCellMarket]

Stem Cell Therapy developers I Peace and iCamuno Biotherapeutics Start Natural Killer Cell Trial for Ovarian Cancer - https://t.co/ieiyzB50Bn

@ipeaceinc_e

[Matthew McCormack @matthewmccorma]

@naturemethods Amazing work...Congratulations to all!

[ryan lister @ry_lister]

In our new work we chart epigenome reconfiguration in human iPSC reprogramming, informing a new 'Transient Naive Treatment' (TNT) reprogramming strategy that corrects human iPSCs functionally and epigenetically. Read it here @Nature https://t.co/VZYmTt8IRe

[Monika Mohenska @m_mohenska]

🚀🔬 Exciting news! 📢 The latest paper from Polo and Lister labs is here! 🧪🔍 Discover groundbreaking insights into transient naive treatment reprogramming. 🌟 Don't miss out on this game-changing study! 📄🔝#CellularReprogramming #Epigenetics
https://t.co/i0DBC34STA

[Journal of Experimental Medicine @JExpMed]

Investigators from @WEHI_research and @MonashCCS have shown that the LMO2 transcription factor, a key driver of human T-lymphoblastic #leukemia, inhibits thymocyte competition in a transgenic mouse model and that this enables LMO2 to promote leukemia. https://t.co/WvDtsB7Hh5

[Matthew McCormack @matthewmccorma]

The loss of @methylnick is such a tragedy. A wonderful scientist, bioinformatician, colleague and friend
#notonlyabioinformatician

[Matthew McCormack @matthewmccorma]

@alexyfyf Such a tragedy Alex.
Hope you're OK

[Australasian Genomic Technologies Association AGTA @agtaGenomics]

We are mourning for the passing of @methylnick. He was humble, knowledgeable and supportive to all that needed training and help in #bioinformatics and #genomics

Our thoughts go out to the grieving family, friends and colleagues.

Gone from our sight but never from our hearts

[Charles de Bock @charles_debock]

@CedricSTremblay I agree Cedric. I will dearly miss Pieter. Gone too early. Stay safe there❤️❤️

[James Lucas @JamesLucasIT]

come camminano le stelle marine

[Matthew McCormack @matthewmccorma]

WE’RE HIRING a Research Assistant to help establish a new cell therapy laboratory at the Alfred Medical Research and Education Precinct, one of Australia’s premier R&D hubs. Join a rapidly growing company at the cutting edge of immunotherapy!

https://t.co/0N4YAJz7jc

[Matthew McCormack @matthewmccorma]

Can anyone explain PubMed sorting by "Best Match" when showing papers that cite another paper?

[Matthew McCormack @matthewmccorma]

@Carmichael_Cath @NDLR_conference Nooo!
Well you made it longer than me