Maximilien Franck

Postdoc interested in aging, immunosenescence and longevity; nutrition, metabolic health and the gut microbiota; and evolutionary biology.

[Maximilien Franck @Maximilien28909]

@jnasr @christianclough @bryan_johnson @UniofOxford @brian_armstrong @ResearchHub Absolutely! Living in cold climates also impacts inflammaging patterns: https://t.co/Fhf4EkEzb9

[Maximilien Franck @Maximilien28909]

@tetmin @christianclough @bryan_johnson @UniofOxford @brian_armstrong @ResearchHub Totally agree. This is groundwork for future tests.

[Maximilien Franck @Maximilien28909]

@christianclough @bryan_johnson @UniofOxford @brian_armstrong @ResearchHub @bryan_johnson
We would really appreciate your support!

[Maximilien Franck @Maximilien28909]

https://t.co/I5EIHWXnvc

Thought-provoking.

[Bryan Johnson @bryan_johnson]

Chronic inflammation was thought to increase with age.
It does.
But there’s a plot twist.

A new study published in Nature Aging compared 4 geographically and genetically distant groups:
+ industrialized societies (Italy and Singapore)
+ indigenous communities (Bolivian Amazon and rural Malaysia)

Chronic inflammation, also known as “inflammaging” markers increased with age only in the 2 industrial groups.

For the 2 indigenous cohorts, inflammation was driven by active infections and parasites. Inflammaging markers did not predict age-related diseases (cardiovascular, kidney, metabolic disease) in this community.

The results suggest age-related inflammation is neither universal nor predestined to our biology. It’s an outcome of poor lifestyle choices in modern societies, and very likely preventable.