Lecturer in Plant Pathology at the University of Sydney. Interested in all aspects of plant-microbe interactions. Former @UniBonn, @postech2020, @MasseyUni.
Super excited to share our work on a broad-host-range strain AS109 that enables efficient transient expression across diverse plant species, opening new opportunities for both fundamental and translational plant research. @Freddie_King00@Tolga_Bzkrt@lderevnina
Please re-circulate. New postdoc position available to study organ positioning in the flower at the University of Sydney. Cell polarity, auxin etc etc! Join our multidisciplinary RESYDE (https://t.co/N5lMQrAfng) team! Apply here: https://t.co/5ZvkT5twPd
Really happy and excited to share our new paper on how plants perceive bacterial quorum sensing signals and activate a multilayered immune response 🌱🦠
Link here: https://t.co/RoOHmsFaql
🚨 New from the lab!
In this preprint, we show how the clubroot pathogen Plasmodiophora brassicae uses a PBS3-like effector (PbGH3) to hijack plant hormone signalling and reshape root development during infection 👏
We found that PbGH3 acts as a structural and functional mimic of the immune enzyme AtPBS3 (GH3.12), evidence of the evolutionary relationship between the clubroot pathogen and Brassicas 🥦
This study is now under review 🤞
kallisto sped up RNA-seq quantification by 50x. Now another 50x speedup... quantify hundreds of millions of reads in a few seconds.
This seems too good to be true. But it's true!
Incredible accomplishment by @pmelsted.
Agrobacterium strain, promoter of selection marker gene, medium for co-cultivation and regeneration, and culture vessel were important for efficient transformation in carnation
https://t.co/BAr21jwbJC
OrthoSNAP v1.6.0 is out. If you process large phylogenomic datasets, this release is built for your workflow.
- bootstrap-aware consensus subgrouping:
- --bootstrap-trees
- --consensus-min-frequency
- --consensus-trees
- --resume for interrupted or repeat analyses (1/2)
New Letter: "High-efficiency, transgene-free plant genome editing by viral delivery of an engineered TnpB" https://t.co/DRGVLQh0wP
Viral vectors to deliver engineered smaller RNA-guided endonucleases eTnpBc, achieving high levels of somatic and heritable editing in plants.
New Letter: "New alleles of Arabidopsis BIK1 reinforce its predominant role in PTI and caution interpretations of other reported functions" https://t.co/J463P6iOBI
Summary: be careful with legacy T-DNA mutants.
[On the importance of BIKs in science, including @MicrobiomDigest]
New OA Resource: "Motif-based substrate mapping of the receptor-like cytoplasmic kinase BIK1 reveals novel components and regulatory nodes of plant immunity" https://t.co/ws1TxHX41Z
...define and use the phosphorylation motif of BIK1 to find novel substrate candidates.
We finally released a little coevolution pipeline, so you can add coevolution to predicted structures. With this you can understand more how proteins may genetically interact, as heteromers, homomers or hypothetical networks (or perhaps not) https://t.co/20LWdjO2mh
Visualizing pairwise genome comparisons? No need to run BLAST separately anymore! 🧬
#gbdraw has implemented #LOSAT, a WASM-powered Rust reimplementation of BLASTN/TBLASTX.
✅ No local installation
✅ No data transfer (Serverless)
Try it here: https://t.co/ahqoRxbDHT
I am happy to share that I am starting a Lecturer position at the University of Sydney @Sydney_Uni. Looking forward to contributing to outstanding teaching and great research happening at our School of Life and Environmental Sciences @SydneySOLES.
Just Published: "The TALE PthA4 of Xanthomonas citri subsp. citri Indirectly Activates an Expansin Gene CsEXP2 and an Endoglucanase CsEG1 via CsLOB1 to Cause Citrus Canker Symptoms," by @RikkyRai2 and @NWangUF. Learn more: https://t.co/El3VC5RSyT
OpenFold3-preview (OF3p) is out: a sneak peek of our AF3-based structure prediction model. Our aim for OF3 is full AF3-parity for every modality. We now believe we have a clear path towards this goal and are releasing OF3p to enable building in the OF3 ecosystem. More👇