Big congrats to grad student @AnnaMBarbeau of @mvh_lab on their review of the current understanding and considerations of how diet influences cancer progression/therapy. So important and timely! Check out here: https://t.co/SEr9ibKirn
Pleased to share our recent work out today in @NatMetabolism. This study addresses a longstanding mystery - NRF2-driven cancers increase cysteine acquisition (via xCT) by ~5x - so where does all that cysteine go?
The paper I’ve been most obsessed with lately is finally out: https://t.co/KgdWKknCJK! Check out this beautiful plot: it shows how much LLMs distort human writing when making edits, compared to how humans would revise the same content.
We take a dataset of human-written essays from 2021, before the release of ChatGPT. We compare how people revise draft v1 -> v2 given expert feedback, with how an LLM revises the same v1 given the same feedback. This enables a counterfactual comparison: how much does the LLM alter the essay compared to what the human was originally intending to write? We find LLMs consistently induce massive distortions, even changing the actual meaning and conclusions argued for.
What can 16,000 papers tell us about scientific narratives and journal peer review? We extracted core scientific content from @eLife’s entire machine-readable, CC-BY corpus and compared human peer review to AI.
https://t.co/VyxhNMzn6f
w/ @sinabooeshaghi@lpachter
Really interesting @Nature paper from @mvh_lab creating metabolite auxotrophs and dissecting the resulting metastatic organotropism:
Nutrient requirements of organ-specific metastasis in breast cancer
https://t.co/rW5n59sH3O
Accompanying @NatureNV
https://t.co/dsHoqGbiiy
Thrilled to share our paper out today. I am immensely grateful to my mentor, Dr. Ömer H. Yilmaz @ohyilmaz , and our fantastic collaborators @JudithAgudo1 & labmates and @DamonRunyon for five years of support. https://t.co/tSFdS65lOg
Happy to announce that I was awarded a pathway to independence award (K99) from the NCI/NIH today to work on studying whole-body metabolism driving cancer cachexia. None of this would be possible without support from @DamonRunyon and mentorship from @Transactivator and mvhlab.