Molecular Biophysics Unit, IISc

Molecular Biophysics Unit (MBU) is a part of IISc that pursues cutting edge research in the areas of molecular biophysics and structural biology

[Molecular Biophysics Unit, IISc @MBU_IISc]

Applications for @iiscbangalore admissions 2026 are open!
Our department invites applications for the Ph.D. program. Apply to join our vibrant research community.

Deadline: Mar 23, 2026

[Centre for Continuing Education (CCE), IISc @cce_iisc]

API & Biosimilar QC/R&D experts:
Hands-on NMR Data Acquisition Workshop.
Industry participants only.
Strictly 10 seats.
Investment: ₹1.5L + GST

Apply now! https://t.co/Azrjl3DC4L

#NMRSpectroscopy #Pharma #biotech #IISc #APIManufacturing #Biosimilars #QC #RND

[Molecular Biophysics Unit, IISc @MBU_IISc]

The abstract submission is extended till 24th April. Register and attend the exciting symposium!

[Molecular Biophysics Unit, IISc @MBU_IISc]

We are organizing a 2-day "AI in Biophysics" symposium from 28-29 April. We bring together leading experts to facilitate interdisciplinary and lively discussions.

Website: https://t.co/o5TMSAq9HQ

Poster abstract deadline: April 18
Registration deadline: April 24

[Molecular Biophysics Unit, IISc @MBU_IISc]

We are organizing a 2-day "AI in Biophysics" symposium from 28-29 April. We bring together leading experts to facilitate interdisciplinary and lively discussions.

Website: https://t.co/o5TMSAq9HQ

Poster abstract deadline: April 18
Registration deadline: April 24

[Molecular Biophysics Unit, IISc @MBU_IISc]

The last date for submitting online applications for Research programmes for the Academic Year 2025-26 has been extended till *06 April 2025* https://t.co/OuU3dPQquf

[Cell Press @CellPressNews]

Flexibility of flanking DNA is a key determinant of transcription factor affinity for the core motif by Debostuti Ghoshdastidar and Manju Bansal at @MBU_IISc
https://t.co/kHpExa4zQ0
@BiophysJ highlight — An official journal of @BiophysicalSoc

[Molecular Biophysics Unit, IISc @MBU_IISc]

Check out the special issue of "Proteins: Structure, Function, and Bioinformatics Vol 93 (1): Jan 2025" commemorating GN Ramachandran Centenary @MBU_IISc.

Link: https://t.co/rVUmSHPjSI

[Anand Srivastava @mbuanand]

Out in Eur. Phys. J. Spec. Top., https://t.co/U6aTufu1Yl. We use our replica exchange with hybrid tempering (REHT) method to extract the Boltzmaan's weighted membrane-bound conformations of peripheral proteins. All work by grad student @mouli_njr, a Physican turned Biophysicist.

[Rishikesh Narayanan @cnl_mbu_iisc]

Published version of the preprint now available! The link to the preprint thread is below.

Congratulations Sanjna @2point0Sam!!

Link: https://t.co/w92YLdn7it

[J. Am. Chem. Soc. @J_A_C_S]

Measuring Hydroxyl Exchange Rates in Glycans Using a Synergistic Combination of Saturation Transfer and Relaxation Dispersion NMR | Journal of the American Chemical Society @MBU_IISc #HydroxylExchange #Glycans #NMR @nmr900 https://t.co/GWVR2ISj4E

[Mahavir Singh @SinghMLab]

We are excited to start the new year by sharing the latest paper from our lab @MBU_IISC, @iiscbangalore in @NAR_Open. Here, we report that the RTEL1 helicase interacts directly and functionally with the replication protein A (RPA). (1/5)

@NIRANJANSAARC

https://t.co/H4pKvHKoah

[Manjveekar @manjveekar]

Our recent work "The alteration of structural network upon transient association between proteins studied using graph theory" is out now in Protein: Structure Function and Bioinformatics @WileyBiomedical https://t.co/ae7z9SSWeZ

@tandon_himani @caps_ncbs @MBU_IISc @iiscbangalore

[Manjveekar @manjveekar]

Our work on the "Comparison of structural networks across homologous proteins" is out in
PROTEINS: Structure, Function, and Bioinformatics | Wiley Online Journal @WileyBiomedical https://t.co/bDCJasBKot

@MBU_IISc

[Anand Srivastava @mbuanand]

#glycotime Out now in GLYCOBIOLOGY! Very chuffed to see this out as it's our first Glycan work !!! https://t.co/u1Tr5IeOlq

Thanks to @RamrayB @hurryram @PenmatsaLab for discussions and insights!

Also, thanks to @AnneImberty & @GlycobiologyUK for the smooth editorial process.

[Anand Srivastava @mbuanand]

https://t.co/zAtR1e8Oe6

Out now in @jbiolchem. Had a wonderful time working with @ShovamayeeMaha and @Sangeethayoga, who did all the heavy lifting !!

Would like to acknowledge @India_Alliance, NSM (HPC grant @IndiaDST) @SankhyaSutraLab @DBTIndia @iiscbangalore @MBU_IISc

[Molecular Biophysics Unit, IISc @MBU_IISc]

We are organizing our annual symposium, "NuBS23," tomorrow from 9 AM onwards at the Faculty Hall, IISc Main Building. Please join us to learn about our latest works and hear from our plenary speakers, @gsahu_iisc and @AshhadSufyan.

[Pritha Ghosh @pritha_2107]

Finally our research on thioamide modification and its implications in membrane permeability and bioavailability of cyclic peptides is out!
Congratulations to the entire team!

https://t.co/Il88SVrK4J

@hiteshvrm @b_khatrii @NishantRaj33828 @SohiniBioPharma @MBU_IISc

[Aravind Penmatsa @PenmatsaLab]

Its a pleasure to announce the publication of our latest work on the cryoEM structure of QacA resolved using Indian camelid antibodies in @embojournal . Fantastic effort by @PujaMajumder91 @shah_med @Pragyaahuja_6 and @Athreya_Arunabh.https://t.co/pB86yjM1n2

[Aravind Penmatsa @PenmatsaLab]

Excited to announce the publication of our study on the architecture of the ratGAT1 in the cytosol-facing, GABA bound state @NatureSMB. Brilliant effort @SmrutiR60158682 and well supported by @DeepthiJoseph @ArchishmanDakua @AthreyaArunabh
https://t.co/xfC2VNjj7b

[Madhurima Kulkarni @MadhurimaKulk]

Very happy to share our study uncovering the mechanism of DNA binding by an IDP! The disordered domain of CytR binds DNA through a fully folded minor conformation. @AthiNaganathan @BODHISATWANANDI @MBU_IISc https://t.co/DP18JotmRX