Michael D'Angelo

PhD in Biochemistry and Mol. Biol. Senior Scientist with oNKo Innate.
All views are my own.

[Michael D'Angelo @mdangelo32]

@ewanbirney Great scotch eggs there!

[bit.bio @bitbio]

NEWS! Our cell therapy pipeline + our lead candidate for acute liver failure is live! The pipeline consists of multiple txCells with potential to address significant unmet need. The possibilities for novel cures are endless.
#CellTherapy #ALF #ACLF
https://t.co/VbK0OjdKYU

[Ryan Wick @rrwick]

New blog post:
https://t.co/Kvkkb9ucNu

I revisit the question of ONT-only accuracy for bacterial genomes, and things have improved a lot since I last looked at this about six months ago!

[Johnson Lab @TravisKJohnson]

Check out the latest preprint from Johnson Lab @LIMSLTU @SABE_latrobe and Piper Lab @MonashSci – a fully synthetic diet that supports #Drosophila development! We demo an application in fly models of human metabolic disorders. #nutrigenomics 🍔🪰🧬https://t.co/5bp84cMFnv

[bit.bio @bitbio]

NEWS: Collaboration Announcement

Today, @bitbio announces a collaboration and option agreement with @BlueRockTx for the discovery and manufacture of iPSC-derived regulatory T cells (Tregs) for use in creating therapeutics.🚀
https://t.co/pv0pH1JTnU
#CellTherapies #Biotech

[Michael D'Angelo @mdangelo32]

@osvaldoics @GuertinLab Feels like something @Addgene or ATCC would be well set up to handle. I know ATCC does have some deposited, modified lines already.

[Michael D'Angelo @mdangelo32]

This is really cool, you can now explore a disease genotype/phenotype association in an isogenic human iPSC system without ever needing to learn how to use CRISPR or culture iPSCs.
(disclaimer - I'm an ex-employee of bit bio and hold shares, but I really do think it's cool!)

[bit.bio @bitbio]

BIG NEWS! We launched our new Custom ioDisease Model Cell offering!
Scientists can order their mutation of choice to be genetically engineered in our consistent and defined opti-ox™️ powered human iPSC-derived cells.
https://t.co/BFq0aPBTgF

#research #DrugDiscovery #iPSC

[richard berry @richberry1983]

View from the new office isn’t too shabby though 😊😊😊

[Michael D'Angelo @mdangelo32]

Amazing thread about minipreps. I look forward to trying some of these tricks

[B is @[email protected] @[email protected] @thuronyi]

Minipreps! They're a fact of life. But if they don't bring you joy, you might want to try new tactics or treat yourself to some fun new toys!

Our lab has done 2,625 minipreps so far. Let me share a few tidbits about our approach and our favorite pieces of equipment. 🧵 (1/n)

[Michael D'Angelo @mdangelo32]

@AuriolAuriol @academic_exit @BioMickWatson The relatively high academic wages and lack of industry competition for talent in Australia means the first tweet doesn't really apply here.

[Torsten Seemann @torstenseemann]

Looking for a software engineer to join me and the talented team at AusTrakka - Australia's national pathogen genomics surveillance system. Based in Melbourne, Australia at @TheDohertyInst @ @UniMelb . 🇦🇺🦠🧫🧬🖥️ 🌴
https://t.co/mBEkkJtUIb

[Michael D'Angelo @mdangelo32]

@jil_hammond @nanopore I'm curious about why you want a P2 when you've got a P48. I thought you can start parallel runs at any time on the P48, so what is the advantage of the P2? Portability?

[Michael D'Angelo @mdangelo32]

@OWallerman Look at that 11 T homopolymer called perfectly in there!

[bit.bio @bitbio]

NEW CELLS! Introducing new precision reprogrammed #FTD #ioDiseaseModelCells and #ioWildTypeCells #ioGABAergicNeurons for early access, ready to be integrated into your neurodegenerative disease research and drug discovery workflows. Read the press release: https://t.co/ThBGHV3iiw

[Michael D'Angelo @mdangelo32]

@felicitydavis2 Wish I could have come over too!

[Michael D'Angelo @mdangelo32]

@felicitydavis2 Did Emily make it over for a visit? Looks like a great time!

[Michael D'Angelo @mdangelo32]

Cheap (per run), accurate long reads will be a game-changer

[Oxford Nanopore @nanopore]

We are pleased to announce that #Flongle R10.4.1 Flow Cells (FLO-FLG114) are available to order on the Store under Early Access. We are delighted to offer our latest and most accurate chemistry to our Flongle users. Learn more: https://t.co/RtwIbsczbV (login required)

[Momeneh Foroutan @S_Foroutan]

#Melbourne for #Iran
#TheTimeHasCome 22nd of Oct!
#WomenLifeFreedom #MahsaAmini

[Michael D'Angelo @mdangelo32]

@Fitaklab Shark, always shark! Not enough cartilaginous fish genomes published for my liking!

[Joseph Schubert 🕷️ @schubertspiders]

Happy International Jumping Spider Day! 🕷️ To celebrate, we have another great citizen science discovery. Donna Juanita photographed this undiscovered species on her property and kindly invited us over to sample it. We later found that it also lives in a nearby nature reserve!