Melvin Gruesbeck

Head of Communication @ Profluent Bio.

[Profluent @ProfluentBio]

Protein language models just got an upgrade. Meet Profluent-E1: a free, flexible, frontier protein sequence encoder.

E1 is built with retrieval augmentation to learn from multiple sequences. Models trained over 4T tokens with only 150M-600M params, E1 is SOTA for zero-shot functional and unsupervised structural tasks. It raises the bar for protein representation learning and is freely available today.

[Jeff Ruffolo @jeffruffolo]

Paper: https://t.co/3dVpS4xQug
Blog: https://t.co/CvSzg1y1Z9
NY Times: https://t.co/8T5Pyf1mS6
Access OpenCRISPR-1: https://t.co/3OAN980eUW

[Ali Madani @thisismadani]

Can AI rewrite our human genome? ⌨️🧬

Today, we announce the successful editing of DNA in human cells with gene editors fully designed with AI. Not only that, we've decided to freely release the molecules under the @ProfluentBio OpenCRISPR initiative.

Lots to unpack👇

[Melvin Gruesbeck @melvingruesbeck]

@AlexRoseJo @CA_DMV Haha, ya, seriously. :D

[Melvin Gruesbeck @melvingruesbeck]

4. As uncomfortable as that may seem I really wouldn’t choose otherwise. I am curious, is this a shared experience? Particularly with people I work/have worked with — but strangers too. Or silence, that will do just as well. :)