PhD Student in computational biology at Birmingham University , paediatric anaesthetist with interest in Regional Anaesthesia, Pain & Genomic medicine.
How could data shape the next generation of genomic and even proteomic discovery?
Watch the discussion below. ⬇️
https://t.co/R6DKoEjkpE
#Genetics#Proteomics
@AvantiWestCoast You have pretty much entirely scrapped the discount for the NHS for regular early commuter. it is ridiculous! Now they cost simply double
Can hsCRP help us identify an "inflammatory phenotype" in knee osteoarthritis?
New data from the NIH-funded MOST Study (n=792) suggests the answer is likely no.
Read more from George et al. - https://t.co/1cb2DdnRDm
The impact oif obesity on the immune system.
Through methylation, obesity imprints memory to CD4+ (helper) T cells, which can last for many years, and promotes immune system dysregulation and inflammation. @emboreports
https://t.co/mqGVy6mLd3
In a 2025 Science study, researchers reported compelling evidence for a gut-joint axis involving bile acid metabolism and GLP-1 signaling in osteoarthritis development, advancing the understanding of osteoarthritis pathogenesis and opening new avenues for therapy.
Learn more in this #SciencePerspective: https://t.co/CW3xWagpBE #ScienceMagArchives
Scientific and medical manuscript preparation: how to increase #clarity and #precision in academic writing. New editorial by Prof Dan Sessler
https://t.co/EOqtXi7F1X
📊 NCEPOD highlighted suboptimal analgesia in this group: only 23% reported good pain control before surgery and 38% reported good pain control after surgery. Early pain team involvement is not optional.
Read more in the #BJAEd: https://t.co/uJ7h2jZsI1
#PatientSafety#PainTeams
How does obesity lead to immune system dysregulation and chronic inflammation?
Macrophage metabolism is rewired, with activation of the NLRP3 inflammasome @ScienceMagazine https://t.co/bkAUgOE1c2
Fat surrounding the large intestine (epiploic) is rich in immune cells and can drive inflammation. Study in people with severe obesity. @Cell_Metabolism
https://t.co/kN1B77XrCm
"When it comes to pain, men and women are far from equal."
Highlighting the role of estrogen for amplifying visceral pain sensitivity in the experimental model
@ScienceMagazine
https://t.co/9kSrFif16X
How neurons transfer mitochondria to cancer cells to promote metastasis, a 2025 @ScienceMagazine Breakthrough runner up
https://t.co/vbraeMKiAI
https://t.co/9xyXxw3SZj
Hey, all the pediatric anesthesia #PedsAnes enthusiasts on X 👋🏻
🚨 Survey alert 🚨
@ESRA_Society Pediatric #regionalanesthesia Working Group.
Please spend a few minutes and help us to understand the current situation of #PedsRegional around the world
https://t.co/1CJU0SKKj6
3 wicked weeks in the USA (Boston Children's and MSK in NYC) learning more on advanced RA in children,including ambulatory perineural catheters service. Thanks again to @_Walid_01 & @JohnHagenMD for your generosity & endless enthusiasm.
In Science, researchers report the observation of dendritic nanotubes in brain tissue from mice and humans. The discovery suggests that the current understanding of the brain’s organization may be incomplete, overlooking a hidden layer of connectivity.
Learn more in a new #SciencePerspective: https://t.co/Vv42SiBcif
@RAPMOnline It would be useful to interrogate whether this method could help in the future phenotyping the pain and its possible dynamic changes over time and or chronification in multiple and distinguished surgical cohorts.