Federica M MSc, DESAIC

PhD Student in computational biology at Birmingham University , paediatric anaesthetist with interest in Regional Anaesthesia, Pain & Genomic medicine.

[Federica M MSc, DESAIC @mersthram]

@AvantiWestCoast The UK railway service is absolutely a joke. I lost count of the trains cancelled and or severely delayed.

[Regeneron Genetics Center @RegeneronDNA]

How could data shape the next generation of genomic and even proteomic discovery?

Watch the discussion below. ⬇️
https://t.co/R6DKoEjkpE

#Genetics #Proteomics

[Federica M MSc, DESAIC @mersthram]

@AvantiWestCoast You have pretty much entirely scrapped the discount for the NHS for regular early commuter. it is ridiculous! Now they cost simply double

[Osteoarthritis and Cartilage Journals @OACJournal]

Can hsCRP help us identify an "inflammatory phenotype" in knee osteoarthritis?

New data from the NIH-funded MOST Study (n=792) suggests the answer is likely no.

Read more from George et al. - https://t.co/1cb2DdnRDm

[Eric Topol @EricTopol]

The impact oif obesity on the immune system.
Through methylation, obesity imprints memory to CD4+ (helper) T cells, which can last for many years, and promotes immune system dysregulation and inflammation. @emboreports
https://t.co/mqGVy6mLd3

[Science Magazine @ScienceMagazine]

In a 2025 Science study, researchers reported compelling evidence for a gut-joint axis involving bile acid metabolism and GLP-1 signaling in osteoarthritis development, advancing the understanding of osteoarthritis pathogenesis and opening new avenues for therapy.

Learn more in this #SciencePerspective: https://t.co/CW3xWagpBE #ScienceMagArchives

[British Journal of Anaesthesia @BJAJournals]

Scientific and medical manuscript preparation: how to increase #clarity and #precision in academic writing. New editorial by Prof Dan Sessler

https://t.co/EOqtXi7F1X

[The Brain Prize @BrainPrize]

The review article on the 2026 Brain Prize winners' science is out: The cellular architecture of touch and pain, by Professor Fan Wang (MIT, US)

[British Journal of Anaesthesia @BJAJournals]

📊 NCEPOD highlighted suboptimal analgesia in this group: only 23% reported good pain control before surgery and 38% reported good pain control after surgery. Early pain team involvement is not optional.
Read more in the #BJAEd: https://t.co/uJ7h2jZsI1
#PatientSafety #PainTeams

[Eric Topol @EricTopol]

How does obesity lead to immune system dysregulation and chronic inflammation?
Macrophage metabolism is rewired, with activation of the NLRP3 inflammasome @ScienceMagazine https://t.co/bkAUgOE1c2

[Eric Topol @EricTopol]

Fat surrounding the large intestine (epiploic) is rich in immune cells and can drive inflammation. Study in people with severe obesity. @Cell_Metabolism
https://t.co/kN1B77XrCm

[Eric Topol @EricTopol]

"When it comes to pain, men and women are far from equal."
Highlighting the role of estrogen for amplifying visceral pain sensitivity in the experimental model
@ScienceMagazine
https://t.co/9kSrFif16X

[Eric Topol @EricTopol]

How neurons transfer mitochondria to cancer cells to promote metastasis, a 2025 @ScienceMagazine Breakthrough runner up
https://t.co/vbraeMKiAI
https://t.co/9xyXxw3SZj

[Can Aksu @canestezi]

Hey, all the pediatric anesthesia #PedsAnes enthusiasts on X 👋🏻
🚨 Survey alert 🚨
@ESRA_Society Pediatric #regionalanesthesia Working Group.
Please spend a few minutes and help us to understand the current situation of #PedsRegional around the world

https://t.co/1CJU0SKKj6

[Federica M MSc, DESAIC @mersthram]

3 wicked weeks in the USA (Boston Children's and MSK in NYC) learning more on advanced RA in children,including ambulatory perineural catheters service. Thanks again to @_Walid_01 & @JohnHagenMD for your generosity & endless enthusiasm.

[Trends Cell Biology @TrendsCellBio]

Cholesterol metabolism regulates macrophage function and inflammation-related diseases https://t.co/FgZpAzTnBz

[Federica M MSc, DESAIC @mersthram]

@baby_blocks Home reading before Monday...

[Science Magazine @ScienceMagazine]

In Science, researchers report the observation of dendritic nanotubes in brain tissue from mice and humans. The discovery suggests that the current understanding of the brain’s organization may be incomplete, overlooking a hidden layer of connectivity.

Learn more in a new #SciencePerspective: https://t.co/Vv42SiBcif

[Federica M MSc, DESAIC @mersthram]

@baby_blocks @JohnHagenMD @_Walid_01 Looking good!!

[Federica M MSc, DESAIC @mersthram]

@RAPMOnline It would be useful to interrogate whether this method could help in the future phenotyping the pain and its possible dynamic changes over time and or chronification in multiple and distinguished surgical cohorts.