Still’s disease is an uncommon, systemic, autoinflammatory disease of uncertain cause. It is often misdiagnosed because of heterogeneous symptoms, including fever, rash, leukocytosis, and arthralgia. Learn more in the latest Interactive Medical Case: https://t.co/vzvnp3Z4Ly
Study assessed association of weight change (loss or gain) with incidence & progression of hand osteoarthritis using data from the OAI and found no assoc. b/w weight change and odds of incidence or progression of radiographic hand OA over 4 yrs
In AC&R
https://t.co/sbjHvhS5oP
The #FDA approval was based on positive results from the Phase 3 SAPHYR trial, which showed that nearly 3 times more patients with #PolymyalgiaRheumatica achieved sustained remission with #sarilumab when compared with placebo.
https://t.co/S0NUHKVSWr
Respiratory syncytial virus causes clinically significant illness in children and adults. In a placebo-controlled trial, a prefusion stabilized F protein vaccine led to an 83% lower risk of RSV infection. https://t.co/aU9BV0LXBU
Scratch test for organomegaly. First do a "control". Won't hear scratching until very close to scope. Next put scope over organ (eg, spleen). Now you'll hear scratching when you reach edge of the organ (much farther from scope vs control). The organ "carries" the sound to scope.
@Janetbirdope I have seen a similar skin finding for a patient who was on MTX and ended up diagnosed with Methotrexate-associated lymphoproliferative disorder (MTX-LPD). He responded very nicely upon cessation of methotrexate.
Hyaluronic Acid Knee Injections Equivalent to Placebo
In the United States, where over $300 million is spent annually on intraarticular hyaluronic acid injections, yet another study shows such therapy to be no better than placebo.
https://t.co/bBEwpId84L
NEW RESEARCH—Methotrexate plus ustekinumab versus ustekinumab monotherapy in patients with active psoriatic arthritis (MUST): a randomised, multicentre, placebo-controlled, phase 3b, non-inferiority trial https://t.co/2orqjht106