David Michaels

Keeping up with crowdfunding, DAOs, NFTs, epidemiology, AI, engineering, and health news

[Emmanuel @ejustin46]

2) Q: What is meant by immune dysregulation and how does this relate to disease?

We recommend this interesting article, which allows in layman terms, to understand this topic https://t.co/1IoEHS6xEV

[David Michaels @MichaelsRocks]

You corrupted my son's mind in your U of T classes.

Everyone who took your classes should get a refund and free access to legit psychology courses.

#UofT

[Dr Jordan B Peterson @jordanbpeterson]

A higher court in Canada has ruled that the Ontario College of Psychologists indeed has the right to sentence me to re-education camp. There are no other legal avenues open to me now.

It's capitulate to the petty bureaucrats and the addle-pated woke mob or lose my professional licence.

Congratulations,
@CPOntario!

You won this round.

Mark my words, however: the war has barely started. There is nothing you can take from me that I'm unwilling to lose.

So watch out.
Seriously.
You've been warned.

https://t.co/Oersk5915F

[David Michaels @MichaelsRocks]

A #Toronto driver and car leapt into Lake Ontario off of Lakeshore and Cherry St. on January 20, 2024.

Fire Dept divers confirmed that there is 1 occupant in the vehicle. It's now a recovery mission.

Was it:
A. Drinking and Driving?
or
B. A heart attack?
or
C. A #COVID sneeze?

[David Michaels @MichaelsRocks]

@1goodtern Long-Term Consequences of Asymptomatic SARS-CoV-2 Infection:

A Systematic Review and Meta-Analysis

17.13% for at least one symptom,
15.09%for loss of taste,
14.14% for loss of smell, and
9.33% for fatigue.

https://t.co/658WTHxhcW

[Rob Wüst @RobWust]

@BraedenCharlton Blocking of capillaries by amyloid-containing deposits (or microclots) could reduced exercise capacity. We found these deposits in muscle tissue, but surprisingly not inside capillaries. They were located in between fibers, were higher in patients, and went up after exercise 5/n

[Rob Wüst @RobWust]

After a long wait, our longitudinal long COVID study is finally published in @NatureComms: https://t.co/0xfTnjTPNB. We find a skeletal muscle alterations in patients with #longcovid, which worsen with exercise. 1/n

[Fen, MD @FvRhijn]

The most important lesson from Appelman et al is not that everyone with PEM should get a two day CPET with muscle biopsies, but that we should listen to patients. 🧵

[Richard Corsi, PhD, PE (Texas) @CorsIAQ]

"We're playing make-believe with COVID".

"The pandemic is far from over."

Grand slam, nail on the head, dead on Op-Ed by @EricTopol. 👇

[Barry Hunt @BarryHunt008]

What's the third leading cause of death overall?

Covid

[Barry Hunt @BarryHunt008]

What's the leading infectious disease cause of death?

Covid

[David Michaels @MichaelsRocks]

Florida has estimated that purchasing prescription drugs from Canadian wholesalers to treat such conditions as HIV/AIDS, diabetes and hepatitis C could save the southern state $150 million US annually.

Maybe Florida Congressmen should support reforming US drug pricing laws.

[David Michaels @MichaelsRocks]

@KashPrime @CTVNews Is there a HEPA filter operating in the room that you spoke from?

You need to set a better example by either wearing your N95 respirator properly or mentioning that you're in a clean room.

Joey Fox explains air filtration and infection mitigation well:

https://t.co/Y9fz4zLrwO

[Kashif Pirzada, MD @KashPrime]

Why we need better, maybe real-time, indoor air quality monitoring.

I went to go see a movie (Godzilla Minus One - highly recommended if you haven't seen it), and picked a theater that a user indicated had a decent CO2 rating a year ago on the Clean Air Map (https://t.co/kizoUrlfms).

I brought my own CO2 monitor to check, and sadly it was much, much worse. The theater was packed and levels kept rising, there wasn't much perceptible air flow, indicating that maybe the system fan was turned off. Anyway, by the end of the showing, it was over 2400 ppm (420 being the CO2 level in fresh air). Meaning that 5% of each breath you take was rebreathed 'backwash' directly from someone else. Could hear a number of people coughing too, including the couple right behind me.

Ventilation improvements are no good if it's not seen as important, and the system is turned off or not maintained properly!

Good luck to everyone that was there I guess, and the elderly and vulnerable people that live with them.

[Stephen Griffin @SGriffin_Lab]

Waves of infection are caused by exposure of a susceptible population to an infectious agent.
For endemic/seasonal infections, we see one or two waves per year as this susceptible pool is replenished by young (unvaccinated) kids, and older/other folks losing their immunity...

[Chris Turnbull @EnemyInAState]

Dire warning from US HCW as the more severe JN1 novel Covid runs rampant

'The building I'm at has five floors, 3rd, 4th and a lot of the ICU full of COVID patients.'

[David Michaels @MichaelsRocks]

@ejustin46 Does this apply to asymptomatic people?

Are they still damaging their bodies?

Will they eventually develop lymphopenia?

Will their health will degrade as they get repeatedly infected with new variants?

At least some asymptomatic people are developing LC

#SARSCoV2

[tern @1goodtern]

🚨🚨
A friend put it this way:
"Public Health organizations should be informing people that
1. Covid is aerosolized airborne (not droplet) and what that means;
2. That vaccines are not sterilizing but are nonetheless protective against serious COVID infections and apparently mitigate Long Covid;
3. That even mild or asymptomatic initial infections can cause organ damage in the future, and can also lead to Long Covid;
4. That proper ventilation and properly fitted masks can prevent transmission."

[Marc Johnson @SolidEvidence]

We are now officially into year 5 of the SARS-CoV-2 pandemic/endemic.

I gave a lecture to my virology class this Fall about the history of the pandemic through the lens of viral genotypes.

I thought I would share that lecture as a thread.

This is a long one.
1/

[Eric Topol @EricTopol]

A randomized, placebo-controlled trial of modulating the gut microbiome is successful for symptom alleviation in #LongCovid
https://t.co/GwCP7v0q87

[David Michaels @MichaelsRocks]

@GayFabFourFan Viral persistence of SARS in the brain and throughout your body is a reason to never catch it.

The heat map quantifies SARS-CoV-2 RNA (N) through ddPCR present in the autopsy tissues of 11 patients who died with #COVID19

https://t.co/taoe03MdRg

#LongCovid will hit you hard.