michelle lam

[michelle lam @michelleslam48]

#OTILT For patients undergoing stem cel transplantation, fevers often occur in a majority of these patients. Empiric therapy with abx like beta-lactams can be used for febrile neutropenia.

https://t.co/bJs4Q8GJjq

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT Roseomonas is a slow-growing, gram-negative cocobacilli that typically has high resistance rates with PCN, pip-tazo, and cephalosporins

https://t.co/VQYIG4vCOf

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT Dexamethasone is used as adjunctive therapy in patients with bacterial meningitis since the subarachnoid space inflammatory response can be a major contributing factor to morbidity and mortality

https://t.co/M3A2maarUC

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT Prolonged infusions can help optimize therapy for certain antimicrobials. It helps obtain an appropriate concentration and can help overcome certain types of bacterial resistance.

https://t.co/3AOTg4TXuL

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT The inoculum effect is when the MIC of abx increases as the number of organisms inoculated increases
https://t.co/n0XJCsg7qD

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT 7-day courses of perioperative abx were as effective as 14-day courses for donor-derived bacterial respiratory infections in lung transplant recipients

https://t.co/2Jm644ZFMx

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT Moxifloxacin reaches high CSF concentrations and has been used successfully for resistant strains of M. tuberculosis causing meningitis

https://t.co/BZmwfsJp9c

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT Drug reaction with eosinophilia and systemic symptoms (DRESS) is recognized as T-cell mediated and not antibody mediated
https://t.co/uybbQoJbum

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT There have been case reports that suggest that G-CSF therapy in febrile neutropenia can lead to splenic rupture.
https://t.co/bRibgTT2Bt
@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT The BLING III trial showed that continuous vs intermittent beta-lactam abx infusions did not significantly reduce 90-day mortality rates

https://t.co/RXI4U6Qtlq

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT Yokenella regensburgei is a member of the Enterobacteriaceae family. They are gram-negative, rod-shaped bacteria that can be found in the environment and intestinal tracts of insects.
https://t.co/ERfpSV1dCB

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT While there are no CLDI breakpoints for doxycycline. Studies have shown that it has good potency for Stenotrophomonas maltophilia.

https://t.co/bXtuxeHXt4

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT Bacillus species is a gram-positive rod that has increasing resistance to PCNs and cephalosporins, but are generally susceptible to carbapenems, FQs, and AGs

https://t.co/ZAuj262gOT

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT Compartment syndrome is a painful condition that occurs when there is an increase in pressure in a closed compartment of the body that can lead to ischemia or, eventually, necrosis.

https://t.co/1sGuCS44jQ

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT Necrotizing pancreatitis often occurs when the pancreas gets inflamed or injured and the pancreatic enzymes leak which harms the surrounding tissue.

https://t.co/PfL60Z9ia4

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT Oxacillin is currently recommended for treatment of MSSA CNS infections but there is also information that cefazolin can have good concentrations in the CSF as well.
https://t.co/I8Yb6nr2Wv

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT Today I learned that tularemia can be spread in various ways like tick bites or from inhaling contaminated aerosols. It can be treated with ciprofloxacin, doxycycline, or gentamicin.

https://t.co/SVmkiZgfFj

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT The Melody valve can provide both adult and children with pulmonary valve disease management. It has a balloon tip that inflates to open the valve and place it into position.
https://t.co/sYTodNN4ww

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT Oral abx therapy was non-inferior to IV abx therapy for complex orthopedic infections when used during the first 6 weeks of treatment.
https://t.co/qyc3hT9KZB

@BWDionne @jeffpears0n @davidwkubiak

[michelle lam @michelleslam48]

#OTILT In patients where a C. diff PCR test is necessary, PO vancomycin can be discontinued with a negative test since it has high sensitivities (about 98.7%).
https://t.co/T70BohL56U

@BWDionne @jeffpears0n @davidwkubiak