Cerebral microbleeds

International platform for updates on Cerebral Microbleeds 🧠🩸– an MRI marker of cerebral small vessel disease. #microbleeds 👨‍💻

[Andreas Charidimou MD, PhD @a_charidimou]

🩸🧠Clinical MRI framework for cerebral amyloid angiopathy (CAA) diagnosis.

@StrokeAHA_ASA

#NeuroTwitter #stroke #Neurology #neuropath #stroke #dementia #Alzheimers #biomarker #brain #MedStudentTwitter #AmyloidAngiopathy #CAA #cSVD

[Nirmal Pandey MD DM Neurologist @nirmalregency]

Our 1st harrowing experience ever.
28 ♀
Post D&C.
After 5D in ICU on venti.
What do we observe?

[Andreas Charidimou MD, PhD @a_charidimou]

🚨New paper:
Everything you actually need to know about Cerebral Amyloid Angiopathy (CAA) — in 10 clinical takeaways. 🧠💥

🙏 Grateful to @StrokeAHA_ASA for the invitation — and for the intellectual freedom to share my expert perspective.

🔗https://t.co/xdNz9HQY4c

🧵 to follow soon

#NeuroTwitter #stroke #Neurology #neuropath #stroke #dementia #Alzheimers #biomarker #brain #MedStudentTwitter #AmyloidAngiopathy #CAA #cSVD

[Andreas Charidimou MD, PhD @a_charidimou]

🩸🧠Cerebral Amyloid Angiopathy: Pillars for management
#WSC2025

🔖 Read our full Guidelines on behalf of the @iCAAassociation & @WorldStrokeOrg via @IntJStroke

🔗https://t.co/SiLmWOCFNt

#WSC2025 #NeuroTwitter #stroke #Neurology #neuropath #stroke #dementia #Alzheimers #biomarker #brain #MedStudentTwitter #AmyloidAngiopathy #CAA #cSVD

[NeuroNews @NN_publishing]

The 2025 @WorldStrokeOrg scientific statement on cerebral amyloid angiopathy (CAA) - a "very prevalent" small vessel disease - is discussed by @a_charidimou at #WSC2025, including stratification of future bleeding risk in probable CAA cases and the role of inflammation

[Surjith Vattoth @drSurjthVattoth]

Imaging Pearl 1: COVID-19 SWI MRI with Critical Illness Associated Cerebral Microbleeds

[Theodoros Mavridis @TheodorosMavri2]

🫀 AFib + prior brain bleed 🧠 or CAA?
🚨New meta-analysis (14 studies, 1,235 pts) finds LAAO may be safe:
✅ Stroke ~2%
✅ Recurrent bleed ~2%
✅ Major bleed ~3%
⚠️ Evidence low — RCTs needed!

#StrokePrevention #AFib #LAAO
@a_charidimou https://t.co/Oda2FRVt05

[Andreas Charidimou MD, PhD @a_charidimou]

🩸🧠Cerebral Amyloid Angiopathy:
Guidelines for Diagnosis and Management

🔖 A Scientific Statement from the @iCAAassociation and the @WorldStrokeOrg via @IntJStroke @SMGreenbergNeur @UCLStrokeRes

☂️These will likely have significant clinical impact by helping to harmonize care for our patients with CAA.

🔗https://t.co/QGJpL4WcSn

#NeuroTwitter #stroke #Neurology #neuropath #stroke #dementia #Alzheimers #biomarker #brain #MedStudentTwitter #AmyloidAngiopathy #CAA #cSVD

[Andreas Charidimou MD, PhD @a_charidimou]

🚨 New meta-analysis

🩸🧠 In selected patients with AFib &
cerebral amyloid angiopathy / intracranial hemorrhage, 🫀LAAO may be a safe and feasible alternative to 💊anticoagulation.

Excellent work @TheodorosMavri2 and team @IntJStroke!

#NeuroTwitter #Neurology #Neurosurgery #stroke #MedStudentTwitter #FOAMncc #MedTwitter #amyloidangiopathy #FOAMncc #cSVD #Cardiology #CardioTwitter

[Theodoros Mavridis @TheodorosMavri2]

Excited to present our newly published study/meta-analysis on LAAO in patients with previous ICrH and/or CAA.

Many thanks to my mentor @a_charidimou. Without his guidance this endeavor would not be possible.

I also want to thank Dr Archontakis-Barakakis and Dr Chlorogiannis...

[Whitfield Lewis, MD 🇦🇬🇺🇸 @whitfieldlewis6]

10/
🔹 GRE / SWI (Gradient Echo / Susceptibility Weighted Imaging)
These sequences detect magnetic distortion from paramagnetic substances—like iron, calcium, or blood.
🩸 Blood breakdown = iron = black on imaging
🧠 Use for:
– Microbleeds
– Hemorrhagic conversion
– Cavernomas
– Calcifications
Know your anatomy: iron is naturally present in regions like the globus pallidus.
🧠 The image below shows microhemorrhages in the thalamus and basal ganglia.
Those small, scattered, circular dark lesions are microbleeds.
The iron deposits distort the local magnetic field, leading to a signal dropout on SWI.

[Christian Boehme @chris7ianb]

@a_charidimou kicks off #ESOC2025 @ESOstroke with a fine talk on application of diagnostic criteria in CAA

[International Journal of Stroke @IntJStroke]

🧠Illicit Drug Use & Cerebral Microbleeds in Patients with Acute Ischemic Stroke & Transient Ischemic Attack

👉New study shows association between cerebral microbleeds and cocaine and opioid use

https://t.co/TWQpcgABqt

[Andreas Charidimou MD, PhD @a_charidimou]

⭕️🧠 CAA progression & neuropath staging (CAA=Cerebral Amyloid Angiopathy)

Here is my take👇 which will try to unpack 🧵 in the coming days.

⛱️ CAA is not a single disease and is not uniform
🌂CAA does NOT invariably progress to bleeding as part of it's natural history, but rather there are hemorrhagic/advanced and non-hemorrhagic phenotypes which progress and behave distinctly
🧊 We only see the tip of the CAA iceberg

#NeuroTwitter #NeuroRad #Neurology #Neurosurgery #stroke #MedStudentTwitter #FOAMncc #MedTwitter #amyloidangiopathy #FOAMncc #neuroscience #brain #Alzheimers #Alzheimer #illustration #neuropath #cSVD

https://t.co/Ofv7SnoK04

[Andreas Charidimou MD, PhD @a_charidimou]

⚡️🩸🧠 Practical framework for diagnosing Cerebral Amyloid Angiopathy-related inflammation (CAA-ri)

We frequently discuss challenging CAA-ri cases with colleagues around the world. This framework summarizes key diagnostic features across the CAA-ri spectrum in a clinically useful manner.

via @ANA_journals @GreenJournal

#NeuroTwitter #stroke #Neurology #neuropath #stroke #dementia #Alzheimers #biomarker #brain #MedStudentTwitter #AmyloidAngiopathy #CAA #cSVD

[Andreas Charidimou MD, PhD @a_charidimou]

🩸🧠Hemorrhagic MRI manifestations of CAA
(CAA=Cerebral Amyloid Angiopathy)

⚫️ Strictly lobar/cortical @microbleeds
🎢 Cortical superficial siderosis
🪱 Convexal subarachnoid hemorrhage
🩸 Lobar intracerebral hemorrhage

🚀More tomorrow at the #WSC23 SVD-CAA session!

#neurotwitter #NeuroRad #MedTwitter #MedStudentTwitter #MedEd #EndNeurophobia #Neurology #Neurosurgery #RadEd #stroke #amyloidangiopathy #FOAMncc #WICH2023

[Nirmal Pandey MD DM Neurologist @nirmalregency]

No clinic today as it is a “Holi”day.
Let us review this uncommon #MRI.
Never 😳👀such SWI images before👇.

65♂.
No significant PMH.
p/w a 'Transient Focal Neurological Event.'
A TFNE.

#neurotwitter #NeuroX #MedTwitter #MedX #Neurology #FOAMmed
A 🧵
1/11

[Nirmal Pandey MD DM Neurologist @nirmalregency]

Here is a pearl tutorial on CAA from the master himself. Plenty of CME credits here. Go challenge yourself. See if you have understood the Boston criteria adequately.
https://t.co/A3n3YfbmTF

[Stroke AHA/ASA @StrokeAHA_ASA]

#STROKE Images: In some small vessel disease, abnormal sulci vessels can mimic cerebral microbleeds on magnetic resonance imaging. 🫧 #AHAJournals

https://t.co/j6iB8wVQIn

[Casey Albin, MD @caseyalbin]

Also, bookmark this ASAP if you are a program director or trainee!🔖

These are some of our favorite resources for learning #neurocriticalcare and many are #FOAM!!!

If we missed your favorite, drop a comment pls