@CardioNeo@Dr_KSGautham They do work in closing the pda (at least some of them). Do they improve meaningful outcomes? We just don’t know, and we go back to the trial design issue
@Dr_KSGautham@CardioNeo Close to what Afif El-Khuffash did in his pilot trial, but in real life I have seen PDA in echo with very large shunt volumes as early as 6-8 hours of life and after 2-4 weeks. In my opinion is just not feasible to include all of those situations in a single trial.
@CardioNeo@Dr_KSGautham I think that many trials are not designed to properly answer the question of PDA. And a lot of dollars/euros are spent in designing/implementing/recruiting/publishing/meta-analazing them. I think THAT is concerning and, at least, ethically questionable
@dataref_ar Si esto fuera serio: Debiera renunciar la directiva de la Conmebol, el encargado de la seguridad privada y pública del evento, los dirigentes de Independiente y la U. Debiera haber sanción económica y deportiva ejemplar para ambos clubes.
Pero repito, si esto fuera serio…
@pokestatstcg What about players per country population? I think Chile has a huge amount of players considering 20M inhabitants and only 1 Major event per year
@natetexsun@drbretty I understand that. What I don’t agree with is to put in a blender (meta-analysis) single trials that don’t answer the question expecting the combined results to answer it. There is a chance that conclusions end up being misleading IMHO
86/1249 jugadores en el Regional de Santiago de Pokemon TCG con Terabox! 6-1-5 contento con mi desempeño a pesar de algunos errores en las últimas partidas por el cansancio. #PokemonTCG
Todos invitados a participar de este 1er Diploma de Hemodinamia en el Recién Nacido Crítico de la Universidad de Chile a través de su plataforma Médichi - Educación Continua Online
https://t.co/6RoILTjKDU
¿Por qué fracasó el primer proceso constituyente en Chile? 🤔 Es la pregunta que buscamos responder con Stéfano Palestini en este artículo recién publicado en BLAR. Mientras muchos culpan a la Convención, nosotros exploramos otra causa. Abro 🧵1/7
https://t.co/WLLBc5M4rQ