millslabchemistry

Synthetic organic, organometallic, and mechanistic research at the University of Houston

[Reggie Mills @reggiemills28]

Based on reactivities reported by Kochi 1979, Bhaswati shows that ever-common nickel(I) formation is based on inherent bimolecular organometallic chemistry of nickel(II), especially true for bipyridyl nickel(II) OA compounds without 2,6-aryl substitution

https://t.co/qFJcvxK7A7

[Reggie Mills @reggiemills28]

In a tour de force of cobalt organometallics, PD Kavita @Kavita0809 has shed light on Csp2–Csp2 and Csp2–Csp3 cross-couplings, revealing weak field ancillary N,N ligands support diverging reactivities of high-spin and low-spin arylcobalt(II) catalysts
https://t.co/o0ZxmqmVh3

[Reggie Mills @reggiemills28]

In some of our first work on manganese catalyst design for C(sp3)–H activation, @Bhaswati95 has made and isolated some intriguing new multinuclear salen complexes including the titular Mn(IV)/Mn(III)/Mn(IV)-μ-oxo @DaltonTrans

https://t.co/6vw29rlN12

[millslabchemistry @millslabchem]

Paper celebrations with a little NA Josh™ - congrats Kavita, Bhaswati, and Reggie 🥳

[Reggie Mills @reggiemills28]

Metal–aryls are crucial productive intermediates in cross-coupling, though for cobalt they have rarely been observed during catalysis.

Congrats to Kavita, Bhaswati on a landmark study of isolable, active cobalt–aryl catalysts for sulfone cross-coupling

https://t.co/jS5uJ2gT9B

[millslabchemistry @millslabchem]

Our previous forays looked at iron and at manganese—now reporting our first cobalt chemistry from the Mills Laboratory 🤩

[Reggie Mills @reggiemills28]

Metal–aryls are crucial productive intermediates in cross-coupling, though for cobalt they have rarely been observed during catalysis.

Congrats to Kavita, Bhaswati on a landmark study of isolable, active cobalt–aryl catalysts for sulfone cross-coupling

https://t.co/jS5uJ2gT9B

[Reggie Mills @reggiemills28]

We had some fun making (CO)5Mn(I)–aryls, which are now accessible from arylboronic esters via transmetalation. Congrats to first-year Jia-Chun—

https://t.co/TRzRZyVQy9

[millslabchemistry @millslabchem]

Welcome new first-year cross-couplers Truong, Jia-Chun, and Rana! We are excited to see the chemistry you discover, but first let's ace those classes! 🤓

[Reggie Mills @reggiemills28]

Activation of nickel(II) is often-ignored in nickel(I/III) cross-coupling. For (FI)nickel(II), we show that well defined organometallic steps form nickel(0), enabling catalyst “activation” that recovers catalysis when radical side-reactions go off-course

https://t.co/unBX3PAgWo

[Chirik Group @ChirikGroup]

Congrats Prof. Mills on your Nickel cross-coupling paper… keep your eyes peeled!!!👀@reggiemills28 @millslabchem

[John Monteith @JMonteith_Chem]

Super excited to share our work on the photocatalytic O- to S-rearrangement of tertiary cyclopropanols to access cyclopropanethiol products! Huge amount of work went into this one from all involved and I am really happy with how it all turned out.
https://t.co/N6KtymbzQw

[Reggie Mills @reggiemills28]

Excited to share that The Mills Lab will start this fall at the University of Houston!

This is possible due to my mentors and training @RousseauxGroup @pchirik @ChirikGroup

Stay tuned and follow below for more news:

https://t.co/7g4zlu7y1J