@DarthMods@gorskon What sources? I see none.
I do see this tho: “Errors are said to be the third leading cause of death in Canada after cancer and heart disease.” Strong stuff. “Are said to be.”
I've been talking about ivermectin a bit recently, and every time I mention it someone will link me to this odd website - ivmmeta dot com
So, a bit of a review. I think this falls pretty solidly into the category of pseudoscience 1/n
@drgomulka@CodingMonkey@OutOfTheDarkAge@swedishchf@GidMK Yes, a low event rate in any single study as it pertains to the validity of the result is a fair critique. I’d have to look back to see how they powered the study and what estimated effect size they were using. Still looking at the totality of the evidence though.
@drgomulka@OutOfTheDarkAge@CodingMonkey@swedishchf@GidMK Already has been giving to thousands in RCTs. If it’s at all effective, presumably the positive effect must be exceedingly modest and thus would never be reliably detected in trials without enormous sample sizes.
@drgomulka@CodingMonkey@OutOfTheDarkAge@swedishchf@GidMK Yes, imprecise. Notably stopped early for futility. That study was given as an example to demonstrate that it had been studied in outpatients, look at everything together. Where is the convincing evidence of effect?
@OutOfTheDarkAge@drgomulka@CodingMonkey@swedishchf@GidMK If by some miracle something comes out that suggests benefit in some segment of the population, I’ll happily get on board. Until that time, “there’s a small chance they could be wrong” is not a reason to start giving millions upon millions of people a drug.
@drgomulka@CodingMonkey@OutOfTheDarkAge@swedishchf@GidMK Meanwhile you seem to be suggesting a treatment based on nothing but the feels at this point. I’ll remind you that I jumped in when you erroneously suggested HCQ had only been studied in in-patients. Maybe you need to have another look at the literature.
@drgomulka@CodingMonkey@OutOfTheDarkAge@swedishchf@GidMK And for the record, I’m well aware of the issues that arise from concentrating on 95% CIs alone in the medical literature when labeling something dichotomously as “effective” or “not effective”. Doesn’t change my point one bit.