How do cells squeeze their large nucleus through tight spaces? In work now published at @J_Cell_Sci, we show that cancer cells can use contraction of the rear cortex to generate pressure in the back and push the nucleus during confined #migration: https://t.co/CGGtx0VzGU
A very very narrow path forwared, cancer cells decide 'pushing' is the way to go. See beautiful work from the @LammerdingLab . Thanks for including us on the ride. The rear cortex: a backseat driver for the nucleus during cell migration https://t.co/1JgpdpR1Pg
Happy May 1st! With summer around the corner, algal bloom will follow soon. Work from our former group member, Fangchen Liu, sheds light on this problem. https://t.co/MIgnjlrurn
Durotaxis demonstrated at a high school class. All you need is two springs of different stiffness and a student who can skate. By @MiquelBoschP following the cartoon by @RaimonSunyer@IBECBarcelona
Interested in measuring forces generated by cells or tissues in 3D fiber nework? Read the tutorial put together by the Leggett and Wu labs, the result of a true collaborative work. https://t.co/GxFjmLl6sR
Can synthetic biology help with building a sustainable environment, see Sean's recent work on engineering bugs to separate rare earth element! https://t.co/9yYd1qQidq
Congratulations to newly minted DOCTOR Anna Dai from Martine's lab, whose beautiful work on the conformal mapping of plant leave growth is very thought provoking. Thanks Martine for the enjoyable thesis defense event in Paris. https://t.co/IYJ5JFISy6
Mechanical compression of healthy and diseased tissue leads to different outcome ! See Mrinal's preprint here https://t.co/QVNCDTP2iE to find out more.
Traction force microscopy is challenging. A less quantitative but simpler approach is to analyze the alignment and remodeling of matrix fibers around contractile cells. Does it actually work, and how? Take a closer look at https://t.co/gpceSlsGJY
So so proud of our own undergraduate researcher, Hannah Davis, gave a presentation on her honors thesis, discovering a unique role of Hyaluronic acid in breast tumor invasion!
My latest book ("Hidden In Plain Sight", MIT Press) is almost here! Thanks to my editor Jermey Matthews for leading a fantastic editing team, which produced a beautiful layout & an amazing cover with img by Greg Cooksey! You can pre-order it here:
https://t.co/7FnBcxYwpB