Mislav Acman

PhD student @UGI_at_UCL. Doing some stuff in: #genetics #omics #resistance #plasmids #HGT. I like cookies and nice weather 🌅🍪

[Mislav Acman @misac42]

Our website is now officially live! 🚀
https://t.co/NiLdwH6zkY
As some of you might know, I decided to start a business that provides expert bioinformatics and data analysis services. If you ever need a bioinformatics expert, you know who to turn to.
Thank you for your support

[Omics Solutions @OmicsSolutions_]

🌟 Exciting News! 🌟
Our website is now officially live
https://t.co/f5XnRRKRzK
We are excited to start actively engaging with an online community! Stay tuned. Next couple of weeks we will be introducing our expert team of https://t.co/AGragz9FTX wizards!🧙‍♂️
#omics #Bioinformatics

[Mislav Acman @misac42]

We highlight current challenges bioinformatics is facing, and the bright future ahead!
Be sure to check it out: https://t.co/gYibPqAVmW
#Bioinformatics #Research #Genetics #Sequencing #HumanGenomeProject #Covid19 #Genomics #GlobalChallenges #OmicsSolutions

[Mislav Acman @misac42]

✨ Hello X/Twitter! We have a new blog post: “Bioinformatics Today: 3.6 Billion Data Entries Later” ✨
In it, we talk about the remarkable progress of bioinformatics research and the deep impact of the Human Genome Project on the biology and medicine. 🌊 🚀 🔍

[Mislav Acman @misac42]

@Elisa_Not_ELISA Nah... You did the right thing 👏

[Mislav Acman @misac42]

Furthermore, we found that epistatic interactions can complicate bedaquiline drug-susceptibility prediction. This highlights the importance of development of rapid drug resistance testing and informed regimen selection to combat drug resistance in TB effectively.

[Mislav Acman @misac42]

Newly introduced antibiotic, bedaquiline, has already been countered by the resistant Mtb strains. Here, we identified cases where resistance-associated variants (RAVs) emerged prior to the bedaquiline's clinical use, indicating a pre-existing reservoir of resistant strains.

[Mislav Acman @misac42]

Our latest paper on drug resistance in tuberculosis (TB) is just published in Genome Medicine – a collective effort lead by the fantastic @LucyvanDorp 🔬👩‍🔬
Full paper here: https://t.co/8wAPRxPFPn
#TB #DrugResistance #Tuberculosis #Bedaquiline #Genomics #AcademicTwitter

[Omics Solutions @OmicsSolutions_]

🌟 Exciting News! 🌟
Our website is now officially live
https://t.co/f5XnRRKRzK
We are excited to start actively engaging with an online community! Stay tuned. Next couple of weeks we will be introducing our expert team of https://t.co/AGragz9FTX wizards!🧙‍♂️
#omics #Bioinformatics

[Cedric C.S. Tan @cedriccstan]

Very proud to share that my first-author paper refuting the existence of a human blood microbiome is now out in @NatureMicrobiol:

https://t.co/akETzqJ4E3

Huge congratulations to all co-authors and special mention to @NiranjanTW and @minghao_chia.

See quoted for a summary🧵.

[Mislav Acman @misac42]

@Judithpineau 👍nice. I had a water pistol in my drawer 😁

[Mislav Acman @misac42]

Our recent publication "Role of mobile genetic elements in the global dissemination of the carbapenem resistance gene blaNDM" is featured on Nature Coms' Microbiology and infectious diseases webpage

Available here 👇 for limited time only:
https://t.co/RbC0HbAhQD

#prouddad 🤓

[Mislav Acman @misac42]

After long silence, finally a tweet from me!
A new paper from my group (and me!) is out in @NatureComms! We used some ~6000 #bacteria sequences to study role of plasmids and transposons on world-wide spreading of NDM #AntibioticResistance gene.

👇👇👇
https://t.co/AfKfnMAaSb

[Mislav Acman @misac42]

@CraigMacLean9 @NatureComms Thank you very much! 🙂

[Mislav Acman @misac42]

After long silence, finally a tweet from me!
A new paper from my group (and me!) is out in @NatureComms! We used some ~6000 #bacteria sequences to study role of plasmids and transposons on world-wide spreading of NDM #AntibioticResistance gene.

👇👇👇
https://t.co/AfKfnMAaSb

[Mislav Acman @misac42]

@ksbakes Thank you! Please, feel free to contact me if you have any questions or need help with running the code. The code is working, but is a bit clunky. I think a software engineer is required to make it more user friendly. 😁

[Mislav Acman @misac42]

@AlexMWailan @NatureComms Thank you very much! I really enjoyed working on NDM. High mobility and many layers of complexity makes it an interesting challenge 🙂

[Mislav Acman @misac42]

This work could not be done without @LucyvanDorp, @BallouxFrancois, @nina_luhmann and 7 other collegues. However, Lucy and Francois get my biggest gratitude for their tremendous support during this project and especially during the past 4 years (which was my PhD). 🌼🍣🥂

[Mislav Acman @misac42]

We noticed that global distribution of NDM-positive plasmids is not random which suggests they are somewhat spatially restricted. This puts forward transposons as main mediators for cross-continental spreading.
This largely agrees with our earlier work
👉 https://t.co/5RzwkUcNYm

[Mislav Acman @misac42]

@ciaranbench On my way!

[Lucy van Dorp @LucyvanDorp]

Our review on #SARSCoV2 genomics now available as open access pre-proof in Current Opinions in Virology ➡️https://t.co/sCnibFFqz4.

With thanks to co-authors @DrCJ_Houldcroft, Damien Richard and @BallouxFrancois @UGI_at_UCL