Mehmet K. Aktaş MD, MBA

Cardiac Electrophysiologist, clinical researcher

[JACC Journals @JACCJournals]

Just published in #JACCINT: SCAI/ASE/HRS/SIR/SVS Expert Consensus Statement, led by @RizikMd, advises training, monitoring, and calls for mandatory implementation of enhanced radiation protection devices to meet #ALARA standards.

Read the full text here: https://t.co/XrVjM2FUKt

[HeartRhythm @hrs_journal]

Impact of empagliflozin and dapagliflozin on sudden cardiac death: A systematic review and meta-analysis of adjudicated randomized evidence

https://t.co/bM1lhX1WXt

[HeartRhythm @hrs_journal]

Antidepressant treatment duration and risk of sudden cardiac death: A nationwide cohort study

@DrMujkanovic

https://t.co/5Z9RdzNkD6

[Giuseppe Biondi-Zoccai @gbiondizoccai]

Must-read review on atrial dyssynchrony and Bachmann bundle pacing in the latest issue of JAMA Cardiology https://t.co/SXU4c5au6i @JAMACardio

[Ramez Morcos, M.D. M.B.A @MorcosRamez]

If you have time to read the entire new HRS/PACES statement on antiarrhythmic drugs, go for it.

https://t.co/LslxUttOhq

If you don’t—and just want the meat of it—I asked ASTRA-6 to summarized the highest-yield, practice-changing points below.

And if you haven’t started using AI to keep up with the nonstop explosion of medical knowledge, try it today.

#EPeeps #Electrophysiology #AIinMedicine

[Ramez Morcos, M.D. M.B.A @MorcosRamez]

ASTR-6 in electrophysiology......

Conduction system pacing explained visually — with the dynamic ECG changes in V1 and V6 as you move from septal capture to CSP.

Full animation in the first comment + HTML file so you can pause it and go step by step.

If you’re in EP and not using AI to learn, teach, or visualize concepts like this… start today.

[Ashley Miller @icmteaching]

I’ve started a Substack: The Dependent Variable.

X is great for short-form discussion, but it’s not ideal for building a coherent archive.

This will be the home for longer-form writing on cardiovascular physiology, haemodynamics, fluids, shock, ultrasound and critical care reasoning. All in one place, easier to follow and return to.

First post: https://t.co/om8CMEgs6W

[Pasquale Santangeli @Dr_Santangeli]

Congrats - important clinical message and very much in line with our experience. We have also seen that a pathogenic TTN mutation is often diagnosed only after patients have undergone several AF/VT ablation procedures. @gasperettimd @KrishnaAragam

[Dr. Zhong @pzhong2016]

inferior extensions of AV node
https://t.co/xx2orX1YwJ

[Maiwand Mirwais @Maiwand66]

An absolute gem of a paper - and a must-read! #Epeeps

[Enrico Ferro, MD @enricoferroMD]

Thrilled to share our latest study in @CircAHA: we ran one of the largest comparative safety analyses of #PFA vs radiofrequency #ablation for #AF, performed
@BIDMChealth (>1,500 #PVI/year). We found a significantly higher stroke risk with PFA. Read on👇

https://t.co/sFECm0SFaY

[HeartRhythm @hrs_journal]

Ethanol infusion of the vein of Marshall in catheter ablation of persistent atrial fibrillation in patients with mitral valve replacement

https://t.co/1gSiG9hz3I

[HeartRhythm @hrs_journal]

Clinical Outcomes of Catheter Ablation versus Transcatheter Edge-to-Edge Repair as the Initial Intervention Strategy in Patients with Atrial Fibrillation and Functional Mitral Regurgitation #OpenAccess

@Hassan_Shirbiny

https://t.co/AwONkHHUd3

[NEJM @NEJM]

Original Article: Anticoagulation for Atrial Fibrillation with Intermediate Stroke Risk (SINGLE-AF trial) https://t.co/fsN8QZhgYh

Editorial: Anticoagulation for Atrial Fibrillation with a Single Risk Factor for Stroke https://t.co/RX8U46dRZb

#ESCCongress | @escardio

[Nassir Marrouche @nmarrouche]

A major development in the 2026 ESC Heart Failure Guidelines is the move toward a simpler EF cutoff: HF with LVEF <50% versus HF with LVEF ≥50% — moving away from the traditional three-way separation of HFrEF, HFmrEF, and HFpEF.

And within this new framework, the guidelines send another clear message:

AF in heart failure is no longer just a rate-control problem.

➡️ When #AFib is driving LV dysfunction, restoring sinus rhythm is recommended, with catheter ablation playing a central role.

➡️ In selected patients with #AFib and HFrEF, catheter ablation should be considered to reduce heart failure hospitalization and improve survival.

➡️ In HFpEF, the evidence gap remains, and treatment decisions should be individualized.

The guidelines also highlight an old friend: digoxin. Once pushed to the sidelines, it again has a role in rate control for patients with AF and heart failure, particularly when other agents are ineffective, contraindicated, or poorly tolerated.

The key message for patients is simple: AF may be a driver of heart failure, not merely a consequence. Recognizing and treating it early could improve symptoms and outcomes.

The next frontier is clear: can eliminating AF change the natural history of HFpEF? #CASTLEHFpEF

#ESC2026 #ESCCongress #AtrialFibrillation #HeartFailure #HFrEF #HFpEF #Ablation @lamcardio @Phiso_de @chris_sohns @shivkumarmd @S_NarayanMD @drjohnm @TulaneTriad @TulaneHeart

[JAMA @JAMA_current]

Presented at #ESCCongress from @JAMANetworkOpen:

Among 412 947 elective #AtrialFibrillation ablation procedures in Japan, in-hospital mortality was 0.029% and remained low during a decade of rapid growth in procedural volume and the number of hospitals performing ablation.

These findings indicate no evidence of a diffusion-related safety penalty during nationwide expansion of elective catheter ablation.

https://t.co/JRJsCGyp6d

[JAMA @JAMA_current]

Presented at #ESCCongress:

Among patients with symptomatic persistent #AtrialFibrillation, adding posterior wall isolation to pulsed field ablation-based pulmonary vein isolation did not significantly reduce recurrence of atrial tachyarrhythmia compared with pulmonary vein isolation alone.

Continuous implantable cardiac monitor follow-up showed recurrence in about half of patients receiving posterior wall isolation and in more than half receiving pulmonary vein isolation alone.

🔗 https://t.co/0nnzLSfwCH

[HeartRhythm @hrs_journal]

Early rhythm control and mental health-related hospitalizations in young and middle-aged patients with atrial fibrillation

https://t.co/QOg1BplTpu

[European Society of Cardiology Journals @ESC_Journals]

CHAMPION-AF and CLOSURE-AF: reconciling contrasting results. Read this viewpoint about left atrial appendage closure #LAAC in #EHJ

👉 https://t.co/YNkpLl4s62
@RoccoMontone @ehj_ed

[HeartRhythm @hrs_journal]

Ultrasound-guided S-ICD implantation: A proof-of-concept study #OpenAccess

https://t.co/Uqcw0Ve7un