i remember being in college, surrounded by kids who just learned about Marxism, and hearing the refrain again and again
"Actually, the reason we don't have a cure to cancer is because Big Pharma companies wouldn't make any money. Capitalism is evil! They make money off treating, but not curing, cancer and so we'll never have a cure, it's all because of corporate greed that people die and suffer."
Cystic Fibrosis is an incredible example of how wrong and ridiculous this worldview is. no, it's not a cure, but holy hell, modern pharmaceuticals have changed the lives of every CF patient in America and legitimately no one ever hears about it.
Dave Ricks has been at @EliLillyandCo for 20% of its 150-year history. He came to the pub, poured his own Guinness, and gave us a 2-hour state of the pharma union: drug prices, clinical trials, patent clocks, the rise of generics, Chinese peptides, compounding pharmacies, the US healthcare system, and how the broad success of GLP-1s have transformed Lilly's business. If you've never heard Dave speak before, you're in for a treat.
Timestamps:
00:00 Intro
05:08 Making R&D decisions
10:11 Clinical trials
24:59 Drug pricing
32:43 Stimulating more R&D
45:16 Pros and cons of US healthcare
58:20 New pharma business models
01:05:53 Stripe + enterprises
01:07:00 China
01:16:31 Generics
01:22:37 GLP-1s
1:37:43 r/Peptides
01:41:25 LillyDirect
01:46:35 Why do investors love LLY?
This nails it.
Me: We should evaluate Phase 3 clinical trial data for products claiming to improve health rather than rely on supplement loopholes and vibes.
Some MAHA person: You just want to enrich Big Pharma
No, I want people with sickness and pain to live longer and easier lives. If pharmaceutical companies build molecules that achieve that outcome at scale, then, yes, they should probably get pretty rich within the bounds of regulatory and patent law.
https://t.co/UXE8u6Avot
Thereโs a huge wide lane for Normie Health Thought, which is that healthy diets are v powerful, exercise is genuinely amazing, building muscle as you get older is awesome โฆ. and also, drugs are great, GLP1s are a miracle, mRNA is cool, vaccines work, and supplements are mostly bullshit (except for creatine and a few others)
But for a variety of reasons, the online breakdown of health politics pits these two sides against each other, as if it makes any sense to have to choose between โlifting weights is goodโ and โthe COVID vaccines workedโ
THE PRINCE IS CHAMPION. St. Ignatuis Junior Prince Babalola-Buchango wins the boys 200 with gritty comeback win: 20.79 to 20.82 for Jack Stadlman of Temecula Valley. Loudest scream of night for popular Prince!
BOOM! Heat 1 of the girls 100-meter dash at the @CIFState Prelims sees St. Ignatius junior Ellie McCuskey-Hay rocket to a wind-legal 11.43! That's the fastest by a @cifccs athlete in 19 years!!! Oh my!!