modoslab

Imperial College Research Fellow researching precision medicine in inflammatory bowel disease using network biology and modelling

[Young European ME Research Group @YoungEmerg]

Day 1, Session 1 of #BREMC15 explores Systems Biology & AI in ME/CFS research, chaired by @TamasKorcsmaros, with talks from Dezso Modos, Veronika Kedlian & Marek Ostaszewski.

Advancing data-driven biomedical research in #MECFS. @Invest_in_ME

[Young European ME Research Group @YoungEmerg]

Ready to kick off two days of ideas, collaboration, and new connections at the YoungEMERG Symposium 2026.
We are excited to welcome participants and speakers from across the community. — let’s begin! 🚀
#YoungEMERG2026

[Young European ME Research Group @YoungEmerg]

📣 Registration for the YoungEMERG Symposium 2026 has been extended until 14 May!

Don’t miss two days of talks, networking, and discussions on ME/CFS research — plus our Cambridge evening activity with punting and dinner ✨

📩 Register via: [email protected]

#YoungEMERG

[Young European ME Research Group @YoungEmerg]

📣 YoungEMERG Symposium 2026 — registration now open!
📅 25–26 May 2026 | Hinxton Hall, Wellcome Genome Campus

Register: https://t.co/IdYaaZ4off
#YoungEMERG #MECFS

[@invest_in_me (Invest in ME Research) 🇪🇺 @Invest_in_ME]

𝗜𝗻𝘁𝗲𝗿𝗻𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗠𝗘 𝗖𝗼𝗻𝗳𝗲𝗿𝗲𝗻𝗰𝗲 𝗪𝗲𝗲𝗸 𝟮𝟬𝟮𝟲
25-29 May Cambridge, UK
5 days of biomedical ME #research
20 Years Investing in ME Research to Discover #mecfs
Young Researchers + #BRMEC15 + #IIMEC18 + #EMERG2026
#IMECW2026 @YoungEmerg @euromeresearch

[modoslab @modoslab]

We published in Science Signalling the understanding of ulcerative colitis cytokine netwokrs. The main idea is from @martonolbei and @KorcsmarosLab. We found master regulatory cytokine such as TL1A.

[Science Signaling @scisignal]

This week’s new issue of #ScienceSignaling has arrived!

A study reveals how fetal cells could activate maternal natural killer cells during early pregnancy, systems immunology reveals cytokine targets in ulcerative colitis, and more. https://t.co/NUXM1yUR96

[Science Signaling @scisignal]

This week’s new issue of #ScienceSignaling has arrived!

A study reveals how fetal cells could activate maternal natural killer cells during early pregnancy, systems immunology reveals cytokine targets in ulcerative colitis, and more. https://t.co/NUXM1yUR96

[KorcsmarosLab @KorcsmarosLab]

@ibdleuven @bverstockt @NickPowellLab @modoslab @johanne_brooks @ImperialMDR We were honored to get an Editorial at the journal highlighting our study and its implications. We are grateful for the great Claudio Fiocchi and Dimitrios Iliopoulos for their insightful summary.

https://t.co/nUEb76y8a5

[KorcsmarosLab @KorcsmarosLab]

Our findings show how genetic variation reshapes cellular signaling in #IBD (see two patient-specific networks 👇), providing a foundation for #PersonalizedMedicine.

Collaborative work with @ibdleuven @bverstockt @NickPowellLab @modoslab @johanne_brooks 🙌

From @ImperialMDR

[Saez-Rodriguez Group @saezlab]

👀 check out projects 1 & 6 on the list:

1️⃣ Multicellular molecular characterisation of inflammatory bowel disease
6️⃣ Designing Efficient Single-Cell Perturbation Experiments with Lab-in-the-Loop AI Agents

📅 Application deadline is 30th September ❗

[modoslab @modoslab]

@DrAnneCarpenter What does it different compared to connectivity mapping such as using LINCS?

[modoslab @modoslab]

@saezlab We are so happy that it is out. Looking forward to testing in it and using in #ibd

[Saez-Rodriguez Group @saezlab]

🎉 The revised version of CORNETO, our unified Python framework for knowledge-driven network inference from omics data, is published in peer reviewed form
🔗 Paper: https://t.co/l2UH0ae9jA
📖 News & Views: https://t.co/0mouNBKXic
💻 Code: https://t.co/DdyOYKh1u9
🧵 Thread 👇

[Ben Mullish @bhmullish]

Great to see this work from Shiv Radhakrishnan and colleagues out in #GutMicrobes - using network analysis to explore #microbiome #metabolome interactions in an #IBD inception cohort: https://t.co/U5xRhFgVzM @IHepatology @ImperialMDR @KorcsmarosLab

[modoslab @modoslab]

@scott_scientist @KorcsmarosLab @Invest_in_ME @martonolbei @ImpOrganoid @ImperialMDR The enveriomental factors can be as well modelled as the initiating source node. The complexity of this disease lies in the interaction of many different systems. Initially I thought about the viral infection as triggers.

[KorcsmarosLab @KorcsmarosLab]

Inspiring few days on how to identify mechanisms for #MyalgicEncephalomyelitis (ME) / Chronic Fatigue Syndrome.
#SystemsBiology session w/ @modoslab
#Cytokines w/ @martonolbei
#organoids & new #Gutonchip + #microbiome platforms @ImpOrganoid @ImperialMDR
Thanks for @Invest_in_ME

[Tauseef Ali MD, FACG AGAF FACP @ibdtweets]

"I often wonder…
Why isn’t this therapy working for my IBD patient?"

Then I remind myself:
It could be…
❗ Too Late – Delayed start of effective therapy
❌ Wrong Choice – Misaligned mechanism of action or incorrect diagnosis
💊 Not Taking Medication – Non-adherence is real
⬇️ Not Pushing Hard Enough – Suboptimal dosing or no T2T strategy

Step back. Reassess. Personalize.
The right therapy at the right time can change everything.

Created by @ibdtweets | Tauseef Ali, MD
#IBD #Crohns #UlcerativeColitis #Gastroenterology #TreatToTarget #PrecisionMedicine

[modoslab @modoslab]

I have a talk out at YouTube which was held at the @PMC_modularity community. If you are interested in #networkbiology and #ibd than maybe worth a check next to some coffee or some boring tasks.
https://t.co/as3iynD3NW

[KorcsmarosLab @KorcsmarosLab]

🚀 The Interdisciplinary Signaling Workshop 2025 is taking shape! 🔬✨
A unique multidisciplinary program connecting #ECR & #PhD students with world-leading experts in #IBD, #microbiome, #organoids, & #PrecisionMedicine

Details & registration by 4 April: https://t.co/R3g5tBODNm

[KorcsmarosLab @KorcsmarosLab]

I’m organizing another Signaling Workshop this July for #PhDs #ECRs & @Y_ECCO_IBD!
✅ Interdisciplinary: #IBD, #cancer, #microbiome, #organoids, #multiomics
✅ Networking: Leading experts from diverse fields
✅ Group projects
🔗 https://t.co/R3g5tBODNm

Check video from 2023👇