Yet another #hemepath club! Led by our resident @MoravekMD and @LoyolaHemePath fellow @NicolasLopezHis This latest gathering of the club was for an in depth discussion of MPNs!
Congratulations to one and only @KMirza for the acknowledgement that is well deserved. Thanks for being an amazing mentor to so many! And thanks @ASCP_Chicago for the recognition!!
No, these are not organisms. They are Rushton/hyaline bodies, which are seen exclusively in odontogenic cysts. They were an incidental finding in a recurrent keratocystic odontogenic tumor and are seen in about 7% of these lesions. Unknown etiology. #pathology#surgpath#ENTPath
@iremessa No, but that is a good point. Loss of INI1 expression would be seen in malignant rhabdoid tumor of the kidney which is typically seen in patients <2 yrs old (~80%). This case was a "clear"-cut clear cell RCC with rhabdoid differentiation and would not show loss of INI1.
Striking rhabdoid differentiation in a case of clear cell RCC. Note the eccentric nuclei, vesicular chromatin, prominent nucleoli, and the distinctive intracytoplasmic hyaline globules. #GUPath#RenalPath#Pathology#SurgPath
Gamna-Gandy bodies seen in an excised atrial myxoma. The result of collagen degeneration due to hemorrhage and subsequent iron deposition. Also note the striking vasoformative rings seen in a myxomatous background. @loyolapathology@kmirza#CardiacPath#SurgPath
Outstanding seminar by @NU_Pathology's Dr. Juehua Gao on "Myeloid neoplasm with germline predisposition" @LoyolaHSD@LoyolaHemePath . You know a talk is a hit when graduate students, residents, clinicians & basic scientists all say it was great! #hemepath#molpath
Nice example of Chédiak–Higashi granules from @ForestHulsMD. CH is a rare entity, caused by mutations in the LYST (CHS1) gene. In contrast "pseudo-Chédiak–Higashi" or "Chédiak–Higashi-like" granules are relatively more common and can be seen in AML. @kmirza @prion87 @MoravekMD /1 https://t.co/u8C1SWoLxi