Nadia Laack, MD MS

Professor and Chair, Department of Radiation Oncology. @MayoRadOnc Opinions stated are my own. Like/RT ≠ endorsement

[Nadia Laack, MD MS @n_laack]

Always energized after meeting up with my Mayo Peds RadOnc colleagues at COG in Chicago @MayoAZRadOnc @MayoCancerCare @MayoFL_RORes @MayoRadOnc

[gelareh-zadeh @gelarehzadeh]

Today’s collaboration announcement between @MayoClinic and @Merck matters to me because it reflects how we’re rethinking drug discovery and precision medicine.
@MayoClinicPlatform

[Nadia Laack, MD MS @n_laack]

Congratulations to Dr @SamirPatelMD, our colleague @MayoClinic Arizona, Dr. Ma, and our friends at MDACC for this important work demonstrating the value of proton therapy in oropharyngeal cancer. @MayoCancerCare @MayoRadOnc @MDAndersonNews

https://t.co/6WpeHRN6Sh

[Bradley Stish @DrStish]

Great to have @lauren_henke and @APrice_BeamOn share their expertise and experience with MRI and CBCT-based online adaptive radiation therapy with our department. @MayoRadOnc

[Yasamin Sharifzadeh @yazshaz]

Come to @ACRORadOnc to see more of my flight attendant outfits 😆

…and to learn about HCC with legendary @ldawsonmd !!!

[Nadia Laack, MD MS @n_laack]

Congratulations to our AI team for winning TWO #VIBEsummit awards for their work developing tools detect prostate cancer recurrence and reduce provider burden with automated daily summaries and trial matching. So proud of this incredible team! @MayoRadOnc @MayoCancerCare

[Nadia Laack, MD MS @n_laack]

Of 3300 physicians and scientists, Dr Paul Brown, my colleague and mentor, was recognized as one of three clinicians of the year at Mayo Clinic Rochester 400+ publications, 4-time teacher of the year, mentor to countless trainees, and dedicated and compassionate clinician

[Nadia Laack, MD MS @n_laack]

All-Star rad onc, chief resident, and most importantly mom extraordinaire- your mom would be proud. Welcome to the family 💗@MayoRadOnc

[Kelsey M. Frechette, M.D. @KelsFrechetteMD]

🚨Life update🚨

Absolutely thrilled to announce that I have the privilege of staying on as faculty at @MayoRadOnc next year!

All because of you, Mom ❤️

Grateful for my heme & peds supporters @n_laack @wgbreen @AnitaMahajanMD @ScottLesterMD @RomanKowalchuk

[Nadia Laack, MD MS @n_laack]

Our own Dr Sharifzadeh’s work on direct-to-unit simulation and adaptive SBRT highlighted in the ASTRO news today. Excellent local control and outcomes while improving access for those at a distance from radiation care ⁦@MayoRadOnc⁩ ⁦@MayoCancerCare⁩

[Nadia Laack, MD MS @n_laack]

Congratulations to Dr Sherry and others who received the Radiation Oncology Institute awards for their research ⁦@MayoRadOnc⁩ ⁦⁦@MayoCancerCare⁩

[Nadia Laack, MD MS @n_laack]

Congratulations and well-deserved!

[Daniel Ma @DanielMaMD]

Congratulations to @KenOlivierMD , the latest FASTRO from @MayoRadOnc! #ASTRO2025

[Daniel E Spratt @DrSpratticus]

#ASTRO25 SCAROP meeting. Good turnout.

Interesting lineup from most junior as Chair to most senior. A number of chairs >15 years and counting.

Nice to hear from some of the innovators and those helping push field forward.

Too many to tag

[Daniel Ma @DanielMaMD]

Congrats to @DavidRoutmanMD @KatieVanAbelMD @LindaXYinMD and our stellar MS4 Cecelia Hidalgo for presenting our real world data with DART (30-36 Gy) for HPVOPC.

282 patients and 97% PFS for int risk group. DART is a standard tx for int risk pts @MayoCancerCare
#ASTRO25

[Speed of Light - The ASTRO Foundation @SpeedofLightFdn]

Congratulations to the #ASTRO25 ROI Publication Excellence Award winners:
- John Nikitas, MD
- Rituraj Upadhyay, MD
- Ethan Ludmir, MD, Alexander Sherry, MD, and Chad Tang, MD

@JNikitasMD @aiims2738 @ebludmir @AlexSherryMD @ChadTangMD

[Stanislav (Stas) Lazarev, MD @StasLazarev]

👏 Outstanding, balanced review by @MartinTomMD calling out #Vorasidenib hype in INDIGO (RCT of Vorasidenib vs Placebo for low grade glioma (LGG) patients with gross disease (i.e. high-risk LGG)

INDIGO data (IDH-mut LGG):
▶️ORR: 0% CR, 1% PR, 10% MR, 83% SD
▶️23% grade ≥3 tox (mostly ↑ LFTs)
▶️Never compared to RT+PCV/TMZ - only placebo
▶️Cross-over allowed (placebo patients were deprived standard of therapy chemoRT twice [at randomization, and at progression]
▶️82% placebo patients progressed at 2 years (these patients should NOT have been observed in the first place)
▶️Short follow-up (14 mo.)

RT toxicities in LGGs often overstated, especially in the context of modern RT techniques (IMRT, VMAT, protons):
🔷️Radiation necrosis ~2%
🔷️Absolute risk of stroke is exceedingly low
🔷️Hormone dysfunction only with significant hypothalamic/pituitary dose (and is a fixable issue); uncommon with modern conformal RT
🔷️Prospective cognitive studies: most show no sustained decline; when seen, often due to tumor progression, not RT

👉 Painting RT as a toxic treatment for LGGs while overselling modest to negligible INDIGO results is misleading for patients and physicians

#ASTRO25 #RadOnc #NeuroOnc

[Nadia Laack, MD MS @n_laack]

My mentee and future pediatric radonc leader Dr McKone’s fantastic presentation demonstrating improved targeting and risk stratification for pediatric neuroblastoma #ASTRO25 @MayoRadOnc @MayoCancerCare

[Nadia Laack, MD MS @n_laack]

@LindaNguyen_l @drshuja3 @MayoRadOnc @MayoCancerCare @MayoClinic It will take almost two years to install, assemble and commission so not until late 2027

[Nadia Laack, MD MS @n_laack]

Looking forward to connecting with our alumni at ASTRO - check your emails and register!

[Nadia Laack, MD MS @n_laack]

100%

[Thor Halfdanarson @OncoThor]

I am not aware of any better speakers on the topic of GI radiation oncology than @KrishanJethwa. Everything just becomes crystal clear. This is why you want to attend @MayoCancerCare CME courses in heme/onc. Quality updates for practitioners. @MayoHemeOnc

[Nadia Laack, MD MS @n_laack]

Don’t forget the Snicker Salad! Always a joy to share our slice of heaven with others

[Kim Corbin @KimCorbinMD]

We are so grateful to have the leadership of @n_laack who’s vegetarian and traditional Hotdish game is on point! I am very🍀to be part of this program and astounded I just celebrated 10 years at @MayoRadOnc!