A breakthrough for Crohn’s disease: Published in @AGA_Gastro, #SKResearch team drives discovery of a new genetic cause of the disease and a biological pathway that could serve as a therapeutic target.
Read more ⬇️ https://t.co/VEV9z7KSui
#IBD#PrecisionChildHealth
BIRC3 (Encoding Cellular Inhibitor of Apoptosis Protein 2) Variants Result in Dysregulated Receptor-Interacting Protein Kinase 1 Signaling Leading to Increased Epithelial Cell Death and Are Associated With Monogenic Crohn’s Disease - Gastroenterology https://t.co/CdCMG31VSg
BIRC3 (Encoding Cellular Inhibitor of Apoptosis Protein 2) Variants Result in Dysregulated Receptor-Interacting Protein Kinase 1 Signaling Leading to Increased Epithelial Cell Death and Are Associated With Monogenic Crohn’s Disease - Gastroenterology @AGA_gastro https://t.co/BPZmzIqSFB
July's Editor's Essential Reading evaluates capsule endoscopy–guided proactive treat-to-target versus continued standard care in patients with quiescent #CrohnsDisease. Read the full article to learn more➡️ https://t.co/T4iPXZDflK
Very excited to share our latest work -demonstrating 50% diagnostic rate for CODE and 3 new CODE genes, MYO1A, GRWD1, and MON1A. @NEJM
The Genetic Architecture of Congenital Diarrhea and Enteropathy | New England Journal of Medicine https://t.co/QC47B03nPb
@AleixoMMuise teaches us that 1 in 20 pediatric #IBD patients @SickKidsNews have monigenic cause of IBD and 10% of published cases of monogenic IBD diagnosed as adults. @SMCH_IBD_Celiac Research Symposium.