Nataša Puzović

Evolutionary & systems biology, gene networks. PhD student at MPIEvolBio.

[Nataša Puzović @natashapuzovic]

A cell requires hundreds or thousands of gene products that interact with each other, but the expression of each gene is inherently noisy.
Here's our preprint where we study how gene-specific expression noise evolves in gene networks:
https://t.co/NiFX1NuHph
🧵(1/5)

[Nataša Puzović @natashapuzovic]

@amrahS_lihkiN It's all a blur at this point :D

[Nataša Puzović @natashapuzovic]

@kalchhauser Hi, I can't drop a message, so I drop a tweet here, I am interested in nongenetic transcriptional variation, coffee sometime? :) cheers!

[Roli Roberts @RoliRoberts]

Here's the @PLOSCompBiol paper that @natashapuzovic just name-checked at #SMBE2023 (selection pressure on expression noise in GRNs): https://t.co/rJ4EGODsBw

[Nataša Puzović @natashapuzovic]

#SMBE2023 goers, interested in gene expression noise and gene regulatory networks? Come to my talk today at 14:20 at AD1! Or find me during the coffee breaks/lunches, I am happy to chat. Cheers!

[Julien Y. Dutheil @jydutheil]

It is out! Thanks @afilipamoutinho and @AdamEyreWalker, this was a great adventure!

#PLOSBiology: Strong evidence for the adaptive walk model of gene evolution in Drosophila and Arabidopsis https://t.co/73leAdxV5u

[Nataša Puzović @natashapuzovic]

@gv_barroso how are you today

[Nataša Puzović @natashapuzovic]

This was work with the amazing Tanvi (@vvTanv) and Julien (@jydutheil)! Stay tuned for more noisy news...

[Nataša Puzović @natashapuzovic]

A cell requires hundreds or thousands of gene products that interact with each other, but the expression of each gene is inherently noisy.
Here's our preprint where we study how gene-specific expression noise evolves in gene networks:
https://t.co/NiFX1NuHph
🧵(1/5)

[Nataša Puzović @natashapuzovic]

These results show that selection at the network level leads to differential selective pressure at the gene level, and local and global network characteristics are an essential component of gene-specific expression noise evolution. (5/5)

[Bilal Haider @bil_haider5]

We demonstrate here the possible mechanism of molecular coevolution, i.e., epistasis which drives evolution in E. coli (bacterial system). Predictions with experimental evidence. Presented by @bil_haider5 @jydutheil collab w/ @gallie_jenna at @MPI_Evolbio #pgg55 and #pggflash

[Nataša Puzović @natashapuzovic]

@fbaumdicker Thanks Franz! Hopefully by the end of January (fingers crossed)

[Nataša Puzović @natashapuzovic]

@AklochKloch @popgroup Thanks Agnieszka!

[Julien Y. Dutheil @jydutheil]

Another preprint from the lab! We built a structural atlas of protein compensatory substitutions: The structural determinants of intra-protein compensatory substitutions https://t.co/QSXrwdrup5

Work led by Shilpi Chaurasia. Here is what we did and found (thread)

[Nataša Puzović @natashapuzovic]

@nanda_trancoso Some university degree (BSc or MSc) in theology is a requirement for becoming a priest in most European countries, regardless of whether the uni is state-funded (secular) or religious. In any case, funding those studies doesn't give the church more leverage in gov decision-making

[Nataša Puzović @natashapuzovic]

@nanda_trancoso Being able to study theology at a state-funded university doesn't mean that the church has power in the state government, it is taught as an academic discipline, like in most parts of the world.

[Nataša Puzović @natashapuzovic]

@TheCherno certain individuals in Plön rn @gv_barroso

[Nataša Puzović @natashapuzovic]

@vandana_r_v ROSALIND is fun :)