Nathan 🧬

Sequencing Chemistry Research Scientist @nanopore Views are my own

[Nathan 🧬 @nathanbaggers]

The only way is up! Use @nanopore for all your modification needs with no additional sample prep required. All these models are now available in Dorado. #nanoporeconf

[Adrien Leger @AdrienLeger2]

🚨 We’re hiring ! 🚨
Join our cutting-edge research team as a molecular biologist at @nanopore HQ in Oxford.
Perfect for a fresh PhD or MSc with a couple of years’ experience. Work at the interface of chemistry, molecular/synthetic biology and AI

👉 https://t.co/eFGBdh59dY

[Genetic Engineering & Biotechnology News @GENbio]

.@nanopore CEO Looks Beyond Native DNA, RNA Sequencing

“I don’t think proteomics will win over genomics," Sanghera said. "They go hand-in-glove. We’ve been overly focused [on genomics], and now we’re going to see an emergence of proteomics...
https://t.co/aJ2cqaHoqN

[Adrien Leger @AdrienLeger2]

We have been busing working on research models to detect all 2'Ome-RNA modified nucleotides on top of PseudoU, m6A, m5C and Inosine using @nanopore dRNA seq.
Preliminary results on Human #rRNA are very exciting. See🦋for more details https://t.co/oQGoKgJXfR

[Nathan 🧬 @nathanbaggers]

Also not to forget Carolin, Perrine and Sarah who are not present on X

[Nathan 🧬 @nathanbaggers]

Excited about @nanopore's collaboration with @uk_biobank to create the first comprehensive epigenetic map of the human genome. Thrilled to see work from our team (@Stoibs11, @AdrienLeger2, @ArtRand ) driving such pivotal advancements!

[Oxford Nanopore @nanopore]

We are proud to announce a collaboration with @uk_biobank to create the world’s first large-scale #epigenetic dataset of 50k participants. The dataset will unlock crucial insights into how #epigenetics drives disease & the breakthroughs to treat them. https://t.co/jEYCZVEUvP

[UK Biobank @uk_biobank]

Today a landmark genetics partnership between @UK_Biobank, @nanopore, @SciTechgovuk, @GenomicsEngland and @NHSEngland to better understand the root causes of cancer and dementia has been announced.

Find out more: https://t.co/7YpwpJM7Aw

[Adrien Leger @AdrienLeger2]

It's Christmas in advance with a very special @nanopore #opendata release ! 🎅
Today we are releasing our 5mC 5hmC and 6mA DNA mod synthetic control datasets with each mods in all possible 5 mers contexts. All nicely wrapped in a comprehensive validation blog post.🎁

[Nathan 🧬 @nathanbaggers]

An exciting new chapter for @nanopore

[Oxford Nanopore @nanopore]

.@nanopore today announced that @RosemaryDokos has been appointed Chief Product & Marketing Officer & Lakmal Jayasinghe as Chief Scientific Officer, effective immediately. Rosemary & Lakmal succeeded Clive Brown as Chief Officer of Technology, Innovation, & Products. Read more: https://t.co/GHjnFMA9JA

[Oxford Nanopore @nanopore]

Discover how you can obtain ultra-rich #singlecell #transcriptome data without compromise. Catch our demo at #ASHG24 to learn how @nanopore's unrestricted read length spans full-length transcripts, providing new insights into single cells.
Learn more: https://t.co/pngscicOyb

[Earlham Institute @EarlhamInst]

🧬 Do you want to learn how to use @nanopore sequencing to detect DNA base modifications?

Our new course will include experimental design with important considerations for generating ultra-long #Nanopore #sequencing reads.

👇 Register your interest:
https://t.co/RSFPRmPTIx

[Aaron Pomerantz, PhD @AaronPomerantz]

The study nicely illustrates how @nanopore overcomes Illumina's errors, which often arise from difficulties aligning reads in repetitive (left) and variant-dense regions (right). "The work thus heralds a new era, in which Illumina short-read sequencing no longer rules supreme."

[Earlham Institute @EarlhamInst]

🆕 Registration has just opened for this two-day comprehensive course, learning how to use @nanopore #sequencing to detect DNA base modifications.

🗓️ 04 - 05 February 2025
📍 Online (via Zoom)
➡️ https://t.co/3YyNVDn8As

[Oxford Nanopore @nanopore]

ElysION moves to Early Access. #nanoporeconf

[Marcus Stoiber @Stoibs11]

T2T assembly kit. Incredibly powerful potential with this data.

[Oxford Nanopore @nanopore]

Updates to Direct RNA
-RNA004 accuracy: 98.9%
-Short-read RNA sequencing (>50 nts)
-Accurately basecall four modifications: m6A, m5C, pseudouridine, and inosine.
#nanoporeconf

[Marcus Stoiber @Stoibs11]

@nanopore Addition of m5C and inosine modified basecallers to m6A and pseU enables expanded view of RNA biology

[Nathan 🧬 @nathanbaggers]

@ewanbirney @Stoibs11 https://t.co/3b25Abq3dg

[Oxford Nanopore @nanopore]

Updates to Direct RNA
-RNA004 accuracy: 98.9%
-Short-read RNA sequencing (>50 nts)
-Accurately basecall four modifications: m6A, m5C, pseudouridine, and inosine.
#nanoporeconf

[Nathan 🧬 @nathanbaggers]

I am looking forward to giving a talk at @EarlhamInst for #EIInnovate 2024. I'll be discussing how our collaboration between @nanopore and @EarlhamInst has been transformative in delivering impact, with a specific focus on mod bases. #newmodmodel
https://t.co/tSirJD2L9a

[Oxford Nanopore @nanopore]

Introducing ElysION: Oxford Nanopore's sample-to-answer sequencing solution.
Learn more: https://t.co/1MwPOyWrnW

[Oxford Nanopore @nanopore]

.@jeffnivala & team at @UW unveiled a groundbreaking ‘proof-of-concept’ method showcasing the capability of #nanopore sequencing to read #polypeptide stands — a major step forward in protein analysis.

Learn more: https://t.co/HdIEeFTuOi