🧵 Thread: Rheumatoid Factor (RF)
Tweet 1 (Intro):
🤔 What exactly is Rheumatoid Factor (RF)?
One of the oldest autoantibodies in medicine, it’s famous for its role in Rheumatoid Arthritis but has many more stories to tell.
🧵 A complete breakdown 👇
@IhabFathiSulima @DrAkhilX @CelestinoGutirr #MedTwitter #RheumTwitter
💡New resources- Management recommendations for kidney transplantation in patients with plasma cell dyscrasia. Useful info on pre-tx eval, post-tx monitoring of recurrence, immunosuppression mgmt. @Kidney_Int@AST_KPCOP w IKMG. More info 👇. https://t.co/9eWhU7EcR9
1️⃣ What do C3 and C4 measure?
✅ C3 and C4 are proteins in the classical and alternative complement pathways.
📌 Decreased levels = consumption (immune complexes) or decreased synthesis.
What a fantastic experience! I'm so grateful for the opportunity to have been part of the GlomCon Fellowship 2025🤩
Now all geared up and ready to dive deeper into the fascinating world of glomerular diseases! 🏊♀️
Thank you to the incredible faculty, thank you @GlomCon
🚨 Cardiorenal Syndrome (CRS): A Deadly Duo 🚨
Did you know the heart & kidneys are so intertwined that dysfunction in one can wreak havoc on the other?
Let's dive into CRS today.
A lucid read for every nephrology & cardiology fellow 🫀🩺
#MedTwitter#ISNTweetorial
ANCA vasculitis & plasma exchange—still a gray zone?
🧪 PEXIVAS said no routine role, but real-world practice often begs nuance.
Did PEXIVAS really settle the debate?
Let’s debate at #ERA25#NephTwitter#RheumTwitter#MedTwitter#Vasculitis
Methods of antibody removal 👇👇👇
Now open access in @NDTsocial
Antibody-mediated Rejection - Treatment Standard
🧐Ongoing phase 2 trials offer hope for effective, therapies targeting different aspects of AMR.
▶️https://t.co/1UNJNYYIK7
Patients with Hz-vasculitis had a
💊mean daily dose of 142 mg
📆mean exposure time of 4.7 years.
The higher the dose, the higher the incidence.
https://t.co/WLGbYJSiE1
🙇♀️C3G and Ig MPGN-How do u treat
First rule out
✅Autoimmune Ds-Sjögren/SLE/Cryo
✅Infection-HBV/HCV/IE
✅Monoclonal gammopathy
➡️Screen complement abnormalities
💊Treatment -Renoprotection for all👇
👍IST-Rapid gfr decline-MMF/steroids trial
💉Complement inhibitors
@NDTsocial
https://t.co/8oJGTFDjqH
🔥 Let’s discuss about Chronic Kidney Disease - Mineral Bone disease (CKD- MBD)
🔥 This is what I thought it was as a student… I was wrong ❌
🔥Did you also think so ? #NephTwitter#MedTwitter#Medpearls
1/ #HFpEF treatment algorithm #tweetorial. This is the algorithm I currently use to treat HFpEF based on evidence we have thus far and my anecdotal experience treating patients over the past 16 years in the @NMCardioVasc HFpEF Clinic.
2/The correct answer is Steroids. Avacopan is a new treatment agent in ANCA associated vasculitis (AAV) that can potentially reduce the use of steroids.