saugat das gupta

visiting consultant Nephrology _Medical College kolkata,Desun hospital Kolkata

[saugat das gupta @nephro_sdg]

Happy to share our 1st published RCT on IgAN https://t.co/rB8tHQF0M7

[Nephrology Journal Club @NephJC]

5/10 A figure paints🖼️ a 1000 words! #NephJC

Emerging evidence from APRIL/BAFF–axis trials underscores how central this pathway is to IgAN biology. Let’s put ORIGIN side by side with the others and see what we learn!

[CKJ @CKJsocial]

The 2025 update of the KDIGO IgA nephropathy guidelines:

an ERA Immunonephrology Working Group perspective

https://t.co/zK0YgArQ6g

@ERAkidney

[Joel M. Topf, MD FACP @kidney_boy]

Anti-hypertensives, dialyzable or not #KidneyWk

[Joel M. Topf, MD FACP @kidney_boy]

Avoid beta blockers and consider deprescribing #KidneyWk

[Joel M. Topf, MD FACP @kidney_boy]

Next up transplant study

New immunosuppressant tegopruvart CD154

#KidneyWk

[Joel M. Topf, MD FACP @kidney_boy]

Summary

#KidneyWk

[Joel M. Topf, MD FACP @kidney_boy]

Lv is next Talitacicept in IgAN next. It blocks April and baff

[Joel M. Topf, MD FACP @kidney_boy]

Conclusions
#KidneyWk

[Joel M. Topf, MD FACP @kidney_boy]

Conclusion. Weird if you ask me as all the data is positive and he did not present safety data that is concerning. #KidneyWk

[Joel M. Topf, MD FACP @kidney_boy]

DAPA-PKD and STOP-PKD will provide definitive data #KidneyWk

[Joel M. Topf, MD FACP @kidney_boy]

Type 1 and type 2 diabetic nephropathy behave the same way

#KidneyWk

[Joel M. Topf, MD FACP @kidney_boy]

Summary slide #KidneyWk

[C. Michael Gibson MD @CMichaelGibson]

Extending DAPT beyond 12 months in multivessel disease improves outcomes without increased bleeding

[MIЯVΛƬ #IC ༄ ｡° @mirvatalasnag]

#AHA25 this trial #CELEBRATE will be practice changing (ambulance care) along w

A) #ADMIRAL Abciximab
B) #On_TIME Tirofiban

📚@NEJM
https://t.co/FMryilYCDm

📚@JAMANetwork
https://t.co/gm2z1Whnsi

📚@JACCJournals
https://t.co/X0TsJUTRuQ

@CMichaelGibson @DFCapodanno @vlgmrc @Costa_F_8 @JSillerMatula

[Dr Sudhir Kumar MD DM @hyderabaddoctor]

Did you know that BP can increase to >300 mmHg (though for a short time) during maximal weight lifting?

✅Yes, systolic blood pressure can rise to extremely high levels, sometimes beyond 300 mmHg, during maximal weight lifting, especially when techniques like the Valsalva maneuver are used.
▶️Controlled studies with experienced bodybuilders have documented average peak systolic pressures of 320 mmHg during double-leg press exercises, with individual readings reaching up to 370–480 mmHg in rare cases.

✅However, in a healthy person, with normal heart functions, this transient rise in BP does not lead to any adverse health issues. BP returns to normal levels soon after the exercise is over.

[saugat das gupta @nephro_sdg]

@Happy_20990 Any follow up action against their scam

[saugat das gupta @nephro_sdg]

@voxya_ @GathbandhanC Any follow up action against their scam

[Muthu Vaduganathan @mvaduganathan]

Wow, the game has changed! #SURPASSCVOT meets its primary & secondary endpoints in first *head-to-head* CV outcomes trial!

Tirzepatide (dual GLP1/GIP agonist) vs Dulaglutide (GLP-1RA)

including 16% lower risk of all cause mortality!

https://t.co/rUFYZVn41N

[saugat das gupta @nephro_sdg]

https://t.co/kRsE35DfLg