الجمع بين الميتفورمين ومثبط SGLT-2 أكثر فعالية سريريًا في خفض مستوى الهيموجلوبين السكري (HbA1c) والوزن والحد من أمراض القلب والأوعية الدموية مقارنةً بأي علاج آخر، وكذلك مقارنةً بالميتفورمين وحده.
NICE 2026
5 changes made in 2026 WHO malaria treatment guidelines:
1) Falciparum transmission:
Earlier ONLY ACT used for treatment.
Now, ACT plus a single LOW DOSE primaquine used. (0.5mg/kg, same for G6PD deficiency as well)
For gametocyte neutralisation in low-transmission settings.
Every cancer organ gets the same sequence: surgery is the standard, then trials show you often don't need it, then surgery becomes the salvage.
Breast, larynx, limb, rectum, esophagus, mesothelioma.
Bladder is next. Patients want their organs. 🧵
8am rounds, post call sleepy look on my face and my consultant who asked me to send her a short note on Plasmodium Vivax by 12pm.
So i guess this is how it's gonna be.
Happy Sunday fellas.
During one of my emergency duties in August end, we had a patient who was the head of a division (VVIP). He had an acute MI.
Thrombolysed the pt, shifted him and he eventually got a TVD and had staged plasty and long duration of admission of around 1 month in the hospital. (1/n)
10 Concepts That Explain The Modern World:
- Parkinson’s Law
- Chesterton’s Fence
- Pareto Principle (80/20 Rule)
- Law of Diminishing Returns
- Butterfly Effect
- Tacitus Razor
- Lindy Effect
- Murphy’s Law
- Dunning-Kruger Effect
- Occam’s Razor
What would you add to this?