Sarah Umetsu

Liver/GI/pancreas and placental pathologist at University of California, San Francisco

[Sarah Umetsu @neuthunter]

@Dr_Brian_Cox @GIJamesMD Super interesting! Yes, as @Dr_Brian_Cox says, p16 can be a sign of Rb loss. My colleagues had a paper showing that neuroendocrine carcinomas in the GI tract typically have Rb loss or HR-HPV but not both. p16 is positive in both situations. Do you have Rb stain or HR-HPV?

[Sarah Umetsu @neuthunter]

@GIJamesMD Great case! Is it HR HPV positive? (Or you could try p16)

[UCSF Pathology @UCSFPath]

We are very excited to announce our incoming residency class!

Welcome to San Francisco!

#Match2023 #PathMatch23 #PathTwitter #pathology

[Sarah Umetsu @neuthunter]

@Calkins_SM So excited to have these wonderful trainees become part of our UCSF team!

[Natalie Patel @natzpat]

48 year old with elevated ferritin #liverpath #pathboards

[Sarah Calkins @Calkins_SM]

Can’t think of a better first tweet than to proudly announcing the newest outstanding additions to the UCSF Pathology family!!!! #Match2020 #VirtualPathMatch #Path2Path #UCSF

[Sarah Umetsu @neuthunter]

@drruizcor @SteveLongMD @UCSFcytopath @cytopathology @BalassanianRon @Sara_Jiang @ekhanafshar @vighnesh_w @sza_jhcyto @dinamoMD @suzannecrumley @Sinchita_Roy @SibaElHussein Any chance she could have chlamydia?

[Sarah Umetsu @neuthunter]

@CArnold_GI What did the mass spec show? It looks like the globular amyloid of LECT2.

[Elizabeth Montgomery, MD @LizMontgomeryMD]

Anastomosing hemangiomas are just plain fun to spot. Sarah Umetsu @neuthunter and her colleagues have even found GNAQ and GNA14 mutations in these cuties.

[Sarah Umetsu @neuthunter]

@CArnold_GI I agree with those who already said it...looks good to me for lanthanum deposition

[Sarah Umetsu @neuthunter]

UCSF has an unexpected opening in our Surgical Pathology Fellowship for 2019-2020. The experience includes a wide range of in-house cases, consultation cases, and intraoperative frozen section diagnosis. Any trainees that are interested should email me ([email protected]).

[Sarah Umetsu @neuthunter]

@slusagar Albumin ISH is great, but will be positive in both HCC and intrahepatic cholangiocarcinoma, so not helpful in this setting. I find it most useful in distinguishing intrahepatic cholangiocarcinoma from a metastatic adenocarcinoma to the liver.

[Elizabeth Montgomery, MD @LizMontgomeryMD]

Super lovely example of anastomosing hemangioma of kidney. It even has extramedullary hematopoiesis and hyaline globules. These tumors are so cute and can be foolers for angiosarcoma.

[Sarah Umetsu @neuthunter]

@BIDMCpath Nice example!

[Sarah Umetsu @neuthunter]

A more subtle case of hepatic amyloid. In the liver, this globular pattern of amyloid is highly specific for ALECT2, an unusual type of amyloid associated with patients of Hispanic ethnicity. The globules are seen in the sinusoids, portal tracts, and around central zones.

[Sarah Umetsu @neuthunter]

@MoharramDr Nope, it was not suspected. We do IF on the FFPE tissue

[Sarah Umetsu @neuthunter]

Impressive example of hepatic amyloidosis. 84 year old man presented with liver failure and hepatomegaly. Kappa restriction shown by immunofluorescence. Patient later found to have a plasma cell neoplasm.

[Sarah Umetsu @neuthunter]

Save the Date! UCSF Current Issues in Anatomic Pathology, May 23-25, 2019, San Francisco

[Christina Arnold, MD🦋 @CArnoldMD]

All kinds of good tips and updates on tumor budding in CRC from @sankakar and Soo-Jin Cho. Read more in @ArchivesPath.

https://t.co/bzNkUV37S5

[Elizabeth Montgomery, MD @LizMontgomeryMD]

Yummy case of doxycycline gastropathy. Check out the fibrinoid change in the tiny vessels that are pointed out with arrows. I was just proud to be able to draw arrows in photoshop.