Born and bred in Sydney. Daft Punk obsessed. Chelsea FC fanatic. Wests Tigers supporter. Sydney FC fan. Make-A-Wish volunteer. Leo. Year of the Snake. Believe.
Eli Lilly just released Phase 3 data for retatrutide, their next-generation obesity drug. 2,339 patients. 80 weeks. The biggest trial in the field.
8 things worth knowing:
1️⃣ It beats every obesity drug on the market. Wegovy (semaglutide): 15% Zepbound (tirzepatide): 22% Retatrutide: 25%
2️⃣ You don’t need the highest dose. The lowest (4mg) already outperforms Wegovy. 18% weight loss with one dose increase. Fewer people quit than on the sugar pill.
3️⃣ At two years, weight was still dropping. No plateau. Patients with BMI over 35 lost 84 pounds. 30% of their body weight.
4️⃣ Some patients stopped taking it because they lost too much weight. That’s never happened with an obesity drug.
5️⃣ It works differently. Ozempic and Zepbound suppress appetite. Retatrutide does that too, but its third receptor (glucagon) flips your metabolism toward burning stored fat. In Phase 2, ketone bodies rose 2-3x, confirming the body was switching fuel sources.
6️⃣ It causes a side effect no other obesity drug does: tingling and numbness (12.5%). New receptor, new trade-off. Worth watching.
7️⃣ In a separate study, it cleared 86% of liver fat. 93% of patients reached normal levels. 1 in 3 adults have fatty liver disease. No approved drug comes close.
8️⃣ Two-thirds of patients on the highest dose were reclassified out of obesity entirely. They started at BMI 40. They finished under 30. That’s not just weight loss. That’s a medical reclassification.
@US_FDA filing expected late 2026.
Chelsea Football Club is delighted to announce the appointment of Xabi Alonso as Manager of the Men’s Team.
The Spaniard will begin his role on July 1, 2026, having agreed a four-year contract at Stamford Bridge.
Welcome to Chelsea, Xabi!
It’s official, it’s a terrible season for Chelsea, the club world champions. No trophies, ninth in the table, danger of not qualifying for any European competition, players speaking out, fans protesting, managerial churn, inexperienced caretaker. Some of the players are culpable, not given enough, not taken responsibility when needed.
But this is largely down to the owners, to their flawed approach to recruitment, to their lack of connection to the fanbase, to their astonishing naivety. Chelsea fans deserve better. They deserve more leaders on the field and any leader in the boardroom. They deserve more expertise in the recruitment department. Owners need a rethink. Club needs a reset. #CFC #FACupfinal #CHEMCI
@shaneciurleo Racing 3 weeks ago over 1500m before her first run over 2000m seemed a little arrogant imo…
I’m no expert but the other horses seemed fitter…
Two Australian men.
The one on the right, Ben Roberts-Smith, the most decorated living Australian war hero who was arrested for alleged war crimes in a public spectacle that will no doubt be remembered as April 7th.
On the left, Nick McKenzie, the journalist who spent 5 years investigating Roberts-Smith and the SAS, made career goals off their backs, books, awards, and calls the arrest "justice".
@1788isalright@Nic_Ashman What a horse Sunline ⭐️
Won a Doncaster as a 3yo with 52kg
Runner up as a 4yo with 57.5kg
Won her 2nd Doncaster as a 6yo with 58kg
Autumn Glow Isn’t There To Be Beaten
There’s a point where you stop talking about potential and start dealing in reality, and that’s exactly where Autumn Glow sits heading into the Queen Elizabeth Stakes. People can pick holes all they like, the distance, the opposition, the what ifs, but the truth is simple. If she turns up and runs to her best, they won’t get near her.
What she’s shown so far isn’t just winning form, it’s control. She travels like a proper horse, puts them away when it matters, and gives the feel there’s still more there. That’s not luck, that’s class. And class doesn’t disappear because the race gets harder, it finds a way to win.
And she’s not your typical racehorse either. Her connections paid $1.8 million at the sales, and when you’re talking that sort of money for a filly, you’re not just in it for the ride, you’re protecting capital and, just as importantly, residual value. In all honesty, if she wasn’t any good, she wouldn’t even be on the track. She’d be kept safe as a broodmare prospect. The fact she’s out there racing and winning tells you exactly what they think of her.
With Chris Waller and James McDonald in the corner, there’s no stone left unturned. That’s as good as it gets in terms of setting a horse up to succeed.
The rest of the field can talk themselves into it all week, but when the gates open, it’s a simple question can they match her. From where I’m sitting, they can’t. Not if she runs up to what she’s already shown.
She’s not grinding out wins, she’s winning with a leg in the air. And if she does that again, they’re all running for second.