Nicholas Gentry, PhD

[Nicholas Gentry, PhD @nichgentry]

@bryan_johnson Could inflammaging be in part driven by a lack of inflammation due to infections and parasites?

The hygiene hypothesis and allergies at scale?

[Nicholas Gentry, PhD @nichgentry]

@MauiPace @cremieuxrecueil Birth control doesn't actually affect reproductive lifespan significantly!

OBC stops ovulation, but not the activation and maturation of dormant eggs, which is the primary driver behind the egg depletion that drives menopause

[Martin Borch Jensen @MartinBJensen]

(Inspired by a conversation today)
If you're excited to help Biotech using AI, keep this chart in mind - the best way to improve cost+time per drug is to reduce risk of trial failure, not to use AI to make a bunch of new molecules.

[GCRLE @GCRLE1]

We’re incredibly proud to announce the 2023 GCRLE Grant recipients! These 28 exceptional researchers from across the globe will advance our understanding of ovarian aging #GCRLEGrants #ReproductiveAging @jenngarrison @buckinstitute
https://t.co/EOAvYGizxt

[Fifty Years @fiftyyears]

1/ Solutions to the climate crisis are already here. But they're stuck in academic labs.

Often, after the basic science is done, there’s just a little more work needed to show the science has commercial potential. But no one funds this!

Introducing Manifest Climate!

[Nicholas Gentry, PhD @nichgentry]

@callmezou See: Istanbul

[Nicholas Gentry, PhD @nichgentry]

@Noahpinion Spent a lot a lot of time there. Hard agree.

Where else can you travel 90 mins from a hub and take your pick between visiting *literally* hundreds of uninhabited tropical islands?

[Nicholas Gentry, PhD @nichgentry]

@ruth_hook_ Not to mention that "intelligence" itself is such a broad, varied, and difficult thing to define that any research on it needs to be taken with a fat grain of salt.

Educational attainment and IQ are so limited

[Nicholas Gentry, PhD @nichgentry]

@erikphoel Evil?

Many people I've spoken to who're not deep in the AI weeds explicitly express these things as the ones they're most worried about *right now*.

Could it be they're just addressing the avg person's concerns quickly as AI blow up? Why is this necessarily 'redefinition?'

[Nicholas Gentry, PhD @nichgentry]

@sarakemppainen Any early detection system for POI would probably functionally mean that we've discovered a more general 'fertility clock', because of its diverse and unknown etiology.

Afaik there's many groups working on a lot of different approaches for that but there's no clear leaders yet!

[GCRLE @GCRLE1]

Announcing the 2nd inaugural Reproductive Aging Conference! This is the ONLY international conference dedicated to the mechanisms of reproductive longevity. Join us from Apr 30 - May 03, 2023 in Chicago, IL. Apply to register at https://t.co/sSOO7S5EUu
@jenngarrison @NUDuncanLab

[GCRLE @GCRLE1]

Happy #InternationalWomensDay! Today, we celebrate the amazing contributions of women to the world and to science.

The fight for equality is far from over. Every day, we must push for a better, more equal world for women everywhere. The GCRLE is working to achieve this goal.🧵

[Jennifer Garrison @jenngarrison]

We are in a historic moment when the conversation about reproductive health is evolving – there is a palpable synergy as taboos around female bodies shatter - periods, miscarriage, sex, menopause – women are pushing for solutions to tackle infertility and menopause @GCRLE1 @WIRED

[Jennifer Garrison @jenngarrison]

📢GCRLE is seeking applications for 2023 Grants!

We fund scientists studying female reproductive longevity to reframe the narrative around #womenshealth

👩‍🔬Science for female empowerment✨

Apply at https://t.co/SIbnJh0D0W
📅Opens Nov 18th
@GCRLE1 @BuckInstitute #womenshealth

[João Pedro de Magalhães @jpsenescence]

Just because an intervention extends lifespan it doesn't mean it affects aging as it might be affecting a specific pathology.

As such, many longevity regulators may be unrelated to the aging process, as shown in this recent study in mice.

https://t.co/nnGLWunlAp

[Richard Sever @cshperspectives]

Massive news: eLife to abolish accept/reject decisions: papers will just be “peer reviewed”. Others can argue about this, but lots of interesting consequences. 1/9 https://t.co/FedRxI62iC

[Kanjun 🐙 @kanjun]

In 2020, @michael_nielsen & I began a 2-month project to write: "how would we fund science?"

2 years & 40,000 words later, it's become: "how can the culture & institutions of science actually change, and ultimately become self-improving?"

Our answer: https://t.co/QnxTbfemTA

[Max Lugavere @maxlugavere]

In a new paper in Nature, scientists looked at candidates for reversing dysregulated gene expression in Alzheimer's disease and guess what outperformed all tested drugs? Exercise.

Why isn't this front page news?

[Will Ratcliff @wc_ratcliff]

A new paper in eLife describes a novel multicellular bacterium discovered in a Japanese cave. It has a unique multicellular cycle (forming ordered colonies that eject unicellular propagules when submerged), and helps us understand how the environment shapes MC evolution.