Most of the world’s 15 big pharmaceutical companies do not have antibiotics in their clinical pipeline
"Can major pharma be absolved of the responsibility of developing antibiotics, especially when it is earning handsomely through a few drugs"@rajeshwari_s14 at CSE's webinar
Someone hacked my mom’s whatsapp yesterday (20.07.2023). My mom has been logged out of her WhatsApp while the other person is using WhatsApp using her no. +91-xxxxxx3745 and blocking everyone who is reaching out.
@WhatsApp@LucknowCyber
A mind-blowing paper has come out today in @Nature
In 2016, JC Venter Institute scientists trimmed a bacterial genome to its barest minimum required for life to synthesize what they called a "minimal genome" (https://t.co/Rk8oZJ0bUj).
Today, a group of scientists from Indiana University reports how that minimal genome evolved over 2000 generations in comparison to the non-minimal genome.
The authors found that even when you reduce a bacterial genome to its absolute minimum where every nucleotide matters, the genome undergoes mutational events generation after generation as much as the non-minimal genome. One simply cannot stop the evolution.
Just over 300 days of evolution (equivalent to 40,000 years in humans) the minimal cell has gained everything it lacked in fitness on day one in comparison to the non-minimal cell.
When comparing the evolved traits between the minimal and non-minimal cells, the scientists found something striking. The evolutionary process increased the cell size of non-minimal cells but not that of the minimal cell. But that is not the striking part.
The scientists were able to identify the key mutation that resulted in cell size evolution. And it turned out that the mutation that helped the non-minimal cells to grow bigger is the same that helped the minimal cells to stay smaller. Growing bigger had a survival advantage for non-minimal cells and not growing bigger had a survival advantage for minimal cells. So, the mutation had a context-dependent effect. This just demonstrates that the evolutionary effects on traits have no absolute direction. All that matter is what is beneficial for the organism's survival.
The conclusion of the paper is metaphorically a quote from the Jurassic Park movie:
“Listen, if there’s one thing the history of evolution has taught us is that life will not be contained. Life breaks free. It expands to new territories, and it crashes through barriers painfully, maybe even dangerously, but . . . life finds a way". (https://t.co/UlxRlb86CT)
https://t.co/zA9OAqSoAu
#Hikeinfellowship60@IndiaDST
"Unbelievable! Despite their crucial role in fostering innovation, researchers have been disregarded by scientific leaders and high officials since August 2022. Shockingly, the calls for an increase in fellowship have fallen on deaf ears. As a result, research scholars are left with no choice but to hit the streets nationwide to fight for their rights. Nevertheless, these brilliant minds remain steadfastly committed to groundbreaking research, determined to make "Jai Anusandhan" a resounding success!"
#Hikeinfellowship60@IndiaDST#NonNetFellowshipHike Everyone knows what the role of Indian researchers is, but it depends on our scientific leaders and how much priority they want to give to their contributions to research and development. It's very easy to say a few words like "innovative research" and "interdisciplinary,multidisciplinary," but the question is how much they are trying to implement these ideas while research scholars are still empty-handed so far @guptaakhilesh63@mamidala90
#Hikeinfellowship60
Indeed,providing a 60% fellowship hike for Indian researchers would be a significant and positive development for the whole country.Such an increase in funding by DST would provide researchers with better financial support,which can have several important benefits for the entire scientific community and the country's development @IndiaDST@srivaric@guptaakhilesh63
Absolutely. I told my PhD guide “I am not working under you. I am working WITH you. We must have that mutual respect in place.”
I give credit to my PhD guide Prof Ghatak that he was not offended with my comment and today even after 13 yrs of my PhD we share a fantastic bond.
.@IndiaDST has started a new program 'WISE Internship in #IPR (WISE-IPR)' to train Women having Science & Technology background and want to get expertise in protection of Intellectual Property Rights.
Last Date: 31 May 2023
Visit: https://t.co/J2yhjrUZu7
#WomenInSTEM#WomenInIPR
We're having fun reviewing abstracts for the Biofilm conference--so much great science! The meeting is going to be amazing! If you didn't make the deadline, no worries, there will be a "late breaking" abstract submission period, so stay tuned (and work on writing your abstract)!
We have a PhD position open in our lab to study transcription regulation in pathogenic bacteria. If you are interested in structural biology and would like to learn X-ray crystallography, apply here https://t.co/Mnc8HRqSpT
Last date 08 July 2022
Who are we?
Indian Scientists.
What we do?
We solve great problems such as cancer and global warming.
What we could not solve in last 50 years?
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.
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How to disburse fellowship so that scholars get their pay on time.