Nick Porter

Scientist at Codexis. Bringing enzymes to bear against modern challenges. Breakfast food aficionado. | All views are my own.

[Nick Porter @NJP_Chem]

So glad to finally get to share this! My heart skipped a beat when we saw the density for the carbene. Massive thanks to @EmmaDanelius and @gonenlab for such great work in solving this structure and to @francesarnold for her support in evolving and pursuing these biocatalysts!

[Tamir Gonen @gonenlab]

Excited to share the latest #MicroED #CryoEM study - collaboration w @francesarnold lab to determine the novel structure of a directed evolution enzyme. @EmmaDanelius started the reaction on the crystals and captured the metal carbene reactive intermediate https://t.co/Ec2QMOBZaF

[Nick Porter @NJP_Chem]

Out now in @J_A_C_S! Many thanks to @francesarnold and our collaborators Emma Danelius and @gonenlab.

https://t.co/WuH5Tfjb6y

[Nick Porter @NJP_Chem]

@francesarnold @gonenlab Thank you everyone for the kind words! This activity has been as surprising as it is exciting, so I'm happy to have finally gotten to share it.

[Nick Porter @NJP_Chem]

Thrilled to share this work! We engineered a heme enzyme to activate diazirines, giving us access to donor-subsitituted carbenes in biocatalysis. Many thanks to @francesarnold and our collaborators Emma Danelius and @gonenlab.

https://t.co/GTh2hCliUV

[Nick Porter @NJP_Chem]

@ProfessorEllery @LifeatLSSU Congrats Prof. Zierden!

[Nick Porter @NJP_Chem]

@JodiKraus1 @LabPetry @PrincetonMolBio @ChemistryUD Congratulations, Jodi!

[Nick Porter @NJP_Chem]

@seannmulcahy @novapbs @francesarnold Thanks, Seann! It’s been a wild ride since CHEM 111. Thanks for helping convince me to change my major to Chemistry!

[ChristiansonLaboratory @ChristiansonLab]

@d_osko @ChemEpi @jmhooker @TheWistar @JMedChem Also thanks to former grad student Nick Porter @NJP_Chem!

[Nick Porter @NJP_Chem]

Thankful for the privilege to work on these fascinating drug targets with so many prospects while working in the @ChristiansonLab!

[ChristiansonLaboratory @ChristiansonLab]

Congratulations to former @PennChemistry grad student Nick Porter, currently a Helen Hay Whitney postdoc @francesarnold group, for his just-published #HDAC review in Curr. Op. Struct. Biol...a veritable exclamation point for his outstanding PhD studies!

https://t.co/tAnQqchmoM

[Nick Porter @NJP_Chem]

@ProfessorEllery Yeah that’s gonna add some serious bias, too. Now you’ve gotta write a section for Critter Control and Removal.

[Chenoweth Lab @DMChenowethLab]

Congratulations to everyone who worked on this paper! @NJP_Chem Thank you @BalabushkaFury for helping with the inside cover artwork design! @ChemicalScience https://t.co/7Z4BnR9CUX “Aza-proline effectively mimics L-proline stereochemistry in triple helical collagen”

[Nick Porter @NJP_Chem]

Alright, now that I’m a stranger in a strange land, I have to start getting oriented and figuring out the basics. Most importantly, how am I going to watch the Game of Thrones premier tomorrow night?

[Nick Porter @NJP_Chem]

Mile 3,709: I made it! It was a great cross-country trip with plenty of stories from the road. Can’t wait to get started @Caltech in May. But first, this New Englander has to get used to this “sun” business.

[Nick Porter @NJP_Chem]

Here we go!

[Nick Porter @NJP_Chem]

Mile 1,111: Made it to the Windy City in the Land of Lincoln. After sampling some deep dish pizza, I got back to the hotel room just in time to see my soon-to-be boss, @francesarnold, on The Big Bang Theory!

[Nick Porter @NJP_Chem]

Mile 0: “California here we come”
-Phantom Planet https://t.co/w2qAW5iSV5