Jacob Hooker

Chemist turned neuroscientist. @MGHMartinos @MGHImaging. Editor-in-chief of @ACSChemNeurosci.

[Jacob Hooker @jmhooker]

1.17 billion people now live with a mental health disorder.
Mental illness is the #1 cause of years lived with disability on Earth.
And in 90 countries, <5% of people with major depression get minimally adequate treatment.
Awareness ≠ treatment. https://t.co/S1ppBEZIQy

[Jacob Hooker @jmhooker]

If you want to follow my content, check out my Substack at https://t.co/danvoeRVQN

[Jacob Hooker @jmhooker]

Want to hear about the evolution of psychiatry and anxiety? Check out my conversation with Jerry Rosenbaum.

[Jacob Hooker @jmhooker]

Want to hear about the evolution of psychiatry and anxiety? Check out my conversation with Jerry Rosenbaum.

[Jacob Hooker @jmhooker]

@Scott_LabUM @rsc_medchem @MadisonFrazier1 @jays_wright @afallenbrooks Nice studies on this Pete and team!! Love seeing the activity in activity based probe and ion channel imaging!!

[ScottLab @Scott_LabUM]

Our latest paper describes automated synthesis and preclinical imaging of a novel [18F]Fluorolidocaine analog via sequential C-H radiolabeling and is out in @rsc_medchem. Congrats @MadisonFrazier1 (1st paper!) @jays_wright @afallenbrooks. Read it here: https://t.co/9KTfc2r56Z

[Eikonizo Therapeutics @Eikonizo]

@Eikonizo is excited to be in Philly for the @alzassociation #AAIC24. A great opportunity to learn from and meet with some of the best and brightest in dementia research. If you see our CEO @RickLundberg, be sure to stop and say hello!

[John O’Brennan @JohnOBrennan2]

Wow.

The Harris team are out of the blocks in lightening quick time with this superb ad
https://t.co/YAuod7w8Se

[Jacob Hooker @jmhooker]

@cathleencrudden Why yikes? This is one of many amazing “reset” buttons for the brain. We have a lot to learn, but insights and mechanisms related to psychedelics could be a major contributor to solving the mental health crisis.

[ACSChemNeurosci @ACSChemNeurosci]

📢Stay up to date with the latest📢 This new collection of #ACSChemNeuro research joins the discussion around #MDMA as a potential breakthrough therapy

Read the latest research ➡ https://t.co/PiwSg7FvIJ

[Eikonizo Therapeutics @Eikonizo]

And that's a wrap on #BIO2024! Our CEO, @RickLundberg, spent a busy few days meeting with #biotech & #pharma industry partners and investors while still making time to enjoy some of the sights in beautiful San Diego.

[Jacob Hooker @jmhooker]

@zenbrainest @US_FDA Yes. This challenge will pervade the space. Time for some trial innovation!

[ACSChemNeurosci @ACSChemNeurosci]

📢New collection of #ACSChemNeuro research as the FDA is expected to announce a decision on a new treatment involving #MDMA today ⏰

Read the latest research ➡ https://t.co/MiFPxVyOnt

[ACSChemNeurosci @ACSChemNeurosci]

FDA Advisory Committee votes against recommending Lykos' #MDMA treatment for PTSD

Read our latest MDMA research here ➡ https://t.co/iFVKFwAa7U

[Jacob Hooker @jmhooker]

@RCarhartHarris curious your take if you listened to the discussion part of the meeting.

[Jacob Hooker @jmhooker]

@ACSChemNeurosci @zenbrainest Super interesting discussion about expectancy bias… check out https://t.co/L8Od4hoCbq

[Jacob Hooker @jmhooker]

@ACSChemNeurosci @zenbrainest Super interesting discussion about expectancy bias… check out https://t.co/L8Od4hoCbq

[Jacob Hooker @jmhooker]

Overall, I thought the discussion was less focused on the tremendous unmet need. Maybe I’m a bit too cavalier, but I certainly felt the benefits outweigh the risks (with plenty of guardrail caveats).

[ACSChemNeurosci @ACSChemNeurosci]

@jmhooker @zenbrainest want to kick off the discussion?

[ACSChemNeurosci @ACSChemNeurosci]

Fascinating discussions online today surrounding the FDA's consideration of a new #MDMA treatment for PTSD 🤔

When is a double-blinded study not enough? How can you blind for a treatment that includes such pronounced and well-known effects?

Let us know what you think! ⬇

[Jacob Hooker @jmhooker]

@ACSChemNeurosci @zenbrainest Super interesting discussion about expectancy bias… check out https://t.co/L8Od4hoCbq

[Brian Wallach @bsw5020]

Today the world can watch a film that has been called “the best movie I have seen in 30 years.”

For Love & Life: No Ordinary Campaign is now streaming on @PrimeVideo.

After you watch the documentary, please review it on the Amazon page for the film.

https://t.co/FO3gvK8Bhj

[BryanRoth @zenbrainest]

Whoo hoo! Major paper now out in @science :
"AlphaFold2 structures guide prospective ligand discovery"
Collaboration with @RothLabUNC @BShoichet Skiniotis, Kruse, @EnamineLtd