Noophronesis

Charting the frontier of artificial intelligence. AI, blockchain, and the programmable civilization. All opinions are my own.

[Noophronesis @Noophronesis]

https://t.co/2eTvtQJusK

[Noophronesis @Noophronesis]

How about the robustness against environmental noise？

[Michael Lin, MD PhD 🧬 @michaelzlin]

Today our lab is excited to share a new study in Cell: “Non-invasive control of gene editing in vivo by photoswitchable Cas12f and focused ultrasound.”

We engineered a compact CRISPR system that can be activated at specific locations in the body using focused ultrasound (🧵)

[Noophronesis @Noophronesis]

Reasoning from latent representations is interesting. The causal encoder-decoder architecture of DeepSeek V4.1 Flash is more favorable of this manipulation.

[Sasha Malysheva @aimalysheva]

starting a new week of sharing notable papers, this series topic is latent communication 🤓

batch 1: the pre-history, where models first started passing each other something richer than text

[1] LLM Augmented LLMs: Expanding Capabilities through Composition (CALM) by Bansal et al, 2024
https://t.co/0tI0jRvQXy composes two frozen models with cross-attention on intermediate representations, the direct ancestor of everything below

[2] Let Models Speak Ciphers (CIPHER) by Pham et al, 2023
https://t.co/zL5ZExVb4x multi-agent debate where messages are embedding-space signals derived from output distributions, the first clean argument that tokenizing a message throws away information the other agent could use

[3] Training Large Language Models to Reason in a Continuous Latent Space (Coconut) by Hao et al, 2024
https://t.co/KRSK9iZNoO feeds the last hidden state back in as the next input embedding, so a model reasons without decoding (one model talking to itself)

[Noophronesis @Noophronesis]

AMD outpaced others

[Noophronesis @Noophronesis]

NVIDIA acquires World Labs; SpaceXAI acquires Runway. How’s this plan? Their latest world models are amazing.

[Noophronesis @Noophronesis]

NVIDIA acquires World Labs; SpaceXAI acquires Runway. How’s this plan? Their latest world models are amazing.

[Noophronesis @Noophronesis]

@MaxForAI 美团如果有魄力收购Manus，可以一跃成为AI第一梯队选手。

[Noophronesis @Noophronesis]

Blockchain is ushering in a supercycle.

[Noophronesis @Noophronesis]

Let me tell you a secret: with a sunlight collection device, a fiber-optic cable can channel sunlight into your nasal cavity, and the effect will be much better. Of course, it also works if you point your nasal cavity directly at the sun. Going a step further, if you know a secret of the Maya, you will master the most valuable secret.

[Noophronesis @Noophronesis]

@aimalysheva The principle behind is that depth unfolds the underlying manifold. Latent manipulation can be performed in the intrinsic space of the manifold. Please read:
Rank Diminishing in Deep Neural Networks

[Noophronesis @Noophronesis]

@aimalysheva @AnthropicAI Jacobians are the differentiable language of models. Editing can be performed via their subspaces.

[Noophronesis @Noophronesis]

@ii_posts Build the future
https://t.co/20HW3N1d6j

[Noophronesis @Noophronesis]

https://t.co/YRthPgUCXX

[Noophronesis @Noophronesis]

@sebkrier https://t.co/20HW3N1d6j

[Noophronesis @Noophronesis]

https://t.co/YRthPgUCXX

[Noophronesis @Noophronesis]

@mattbotvinick @ARozenshtein @AnthropicAI AI law should adapt to the emerging structures of agent societies.
https://t.co/20HW3N1d6j

[Noophronesis @Noophronesis]

https://t.co/YRthPgUCXX

[Noophronesis @Noophronesis]

@ahall_research @AnthropicAI Hope this is helpful to your topic in Anthropic
https://t.co/20HW3N1d6j

[Noophronesis @Noophronesis]

https://t.co/YRthPgUCXX

[Noophronesis @Noophronesis]

AI时代是属于草根和民科的时代，科学大爆发正在进行中。风起于青萍之末，浪成于微澜之间。

[Progyan @plugyawn]

I spent the last six months trying to deconstruct Taalas's patents. We think it can be better: 100x fewer memfetches than their bitROM, better software by better quantization than their hardware team could.

So we wrote a compiler that:
> takes a huggingface checkpoint,
> quantizes the model
> descends the weights down metal layers to RTL and GDS, do your DRC, Yosys, PEX, make the electrical waveform execute a mat-vec from your huggingface checkpoint (thanks Cambricon tech papers)

in ~7000 lines of human-readable code.

we're looking for someone with contacts with a foundry/access to 7nm PDKs or contacts at a cheap EuroPTW shuttle? I'm broke and unemployed.

@itsclivetime this is what i think is the future of perplexity per picojoule. @zerohedge @zephyr_z9 you guys wanna see 40,000 tokens/sec?

[Noophronesis @Noophronesis]

This is a development of particular interest.

[Blonskr @Blonskr]

我在 BNB Chain 上做了历史上第一个真实的链上 4位处理器

一个 Token,就是一颗晶体管。
无数颗晶体管连起来，就是一个电路。
无数个电路连起来，就是一台真正的处理器。

2251 个全部由与非门和触发器组成的处理器，逐周期验证过。规格对标 1971 年的 Intel 4004。
它刚刚跑完了斐波那契:1、1、2、3、5、8、13。

它按 BNB Chain 的出块跳动——0.45 秒一拍，目前约等于2.22 Hz。可能这是全宇宙最慢的 CPU。但这是我的一小步，但，是 @BNBCHAIN 的一大步。未来是星辰大海啊！

全球唯一一台没有人能拔掉电源的处理器。我给他取名叫：巨兽 Behemoth

下周，我会发布完整协议发出来。让任何人可以使用这个协议创建自己的真实链上处理器，并且可以互相调用。像拼乐高一样，造出更高规格的链上CPU。
@youyou5202 @web4miko @0xsandy1913 @Cryptowushi @colinwu @heyibinance @cz_binance @BNBCHAINZH

[Noophronesis @Noophronesis]

Bitcoin Is Digital Monetary Energy

[Michael Saylor @saylor]

https://t.co/QMVtmKPGn2

[Noophronesis @Noophronesis]

@saylor Programmable money is indispensable
https://t.co/Cxza8kN4jE

[Noophronesis @Noophronesis]

https://t.co/2eTvtQJusK

[Noophronesis @Noophronesis]

Bound to happen

[CZ 🔶️ BNB - Parody @czbinanceprd]

one massive shift can change everything.

crypto has done it before, and it can happen again.