@ShanksLane1@BasedBiohacker The reason I ask is that in many cases modafinil potentiates caffeine.
I have a friend who drank 4-5 energy drinks a day, and didn't feel anything.
100 mg modafinil and he was down to half an energy drink a day, felt the caffeine subjectively again.
Chinese company Yueban has introduced the smart toilet Xiaoban, which drives itself to the user.
By pressing a button, Xiaoban drives to the user, and after use, it eliminates odors and returns to the charging station. The cost is around $4,000.
@TheDrMAWZ@AbudBakri@PGC1a_RB Melatonin acts differently at higher doses, it does not scale linearly as a hypnotic. That's why some people take over 100 mg in the morning.
@Iammarcmalone@AbudBakri@DrJesseMorse At high enough doses, melatonin can be non-sedating. There is a known inverted response curve, but it is not well characterized past the point of use as a sleep aid I think.
10 mg is still hypnotic.
@yacineMTB Shocking how often a single logistic curve with some simple feature engineering matches thousands of convoluted research papers on open problems.
There have been research surveys and reviews on psychedelics for Alzheimer's treatment dating back pretty far.
It seems like more than just neuroplasticity, there is evidence of increased mitochondrial integrity / biogenesis, decrease in neuroinflammation, and active research is being done on non-hallucinogenics 5HT affecting compounds as well, like Zalsupindole and JRT
This is a good survey of research prior to 2024 on classic hallucinogens for AD dementia
https://t.co/x9AStOzqHY
There have been research surveys and reviews on psychedelics for Alzheimer's treatment dating back pretty far.
It seems like more than just neuroplasticity, there is evidence of increased mitochondrial integrity / biogenesis, decrease in neuroinflammation, and active research is being done on non-hallucinogenics 5HT affecting compounds as well, like Zalsupindole and JRT
This is a good survey of research prior to 2024 on classic hallucinogens for AD dementia
https://t.co/x9AStOzqHY
@realGlazed@cremieuxrecueil@VirtualElena Modafinil increases histamine release in the hypothalamus, is a moderate DAT inhibitor, and the orexin pathway is not a simple light switch either.
If you take a DORA you will likely fall asleep even with a significant moda dose, but it might impact sleep efficiency