SARS-CoV-2 quickly invades nerves, reaching the brain before it spreads in blood.
Blocking Neuropilin-1 greatly reduces the virus’s entry into nerve cells.
https://t.co/VlNODPlDTh
"Notably, in one of these studies [81] a better binding activity of tenofovir with the P323L mutated RdRp protein was observed in comparison with remdesivir, further suggesting tenofovir use in COVID-19 treatment."
Their conclusion?
"Our study suggests that, in men living with HIV, TDF/FTC may protect against COVID-19-related events. Randomized trials are needed to investigate the effectiveness of TDF as prophylaxis for, and early treatment of, COVID-19 in the general population."
"Outpatient treatment with metformin reduced long COVID incidence by about 41%, with an absolute reduction of 4.1%, compared with placebo."
Metformin is cheap, safe & widely available.
A really well run clinical trial 👇
https://t.co/l7tMgh4BfG
📣 New paper in @NatureMedicine
Three-year outcomes of post-acute sequelae
of COVID-19
By Miao Cai @Biostayan@EricTopol and me
A 🧵
https://t.co/6UBj0MgAYQ
The Long Haul, a book on #LongCovid by @r_prior, reviewed by @mendenhall_em@TheLancet
Appropriately spotlights the extraordinary patient activism
"It's really possible they changed the history of medicine"—@zalaly
https://t.co/ZhV0rkssWm
I talked to the @nytimes about the new Covid surge and why symptoms can vary from one infection to the next.
Piece by Dani Blum
https://t.co/Wy89NxGR5l
Violet Affleck: "To confront the Long COVID crisis I demand mask availability, air filtration and far-UVC light in government facilities, including jails and detention centers and mask mandates in county medical facilities. We must expand availability of tests and treatment.
And most importantly, the county must oppose mask bans for any reason. They do not keep us safer. They make them vulnerable members of our community less safe and make everyone less able to participate in Los Angeles together. Thank you." 🔥🔥🔥
Phase 2 trial of Nasodine Nasal Spray in Covid-19 has achieved its primary endpoint
Results demonstrated that Nasodine significantly reduced viral shedding versus placebo, with 100% of Nasodine subjects clearing the virus after the completion of treatment https://t.co/YSSfhkQYmU
A promising way to block muscle fatigue seen in #LongCovid & other diseases
Infections & neurodegenerative diseases cause inflammation in the brain. But for unknown reasons, patients w/ brain inflammation often develop muscle problems that seem to be independent of the CNS. 1/
1. Vaccines should target Flirt variants
2. FDA must approve pediatric Novavax and expedite approvals before fall
3. COVID vaccine should be updated and approved for everyone every 6 months instead of once a year
4. COVID vaccines should be rolled out in August before school year
As a member of the HIV positive community and advocate for those living with a chronic SARS-Cov-2 infection, quite easy to observe that history has repeated itself in every single way, including the response by our government. That Band Hasn't Stopped Playing, Baby.