Neurovascular Research Unit

Twitter feed for the Neurovascular Research Unit #cenkayata @chungmdphd #andreaharriott @harvardmed @MGHNeurology @MGHImaging

[Takahiko Imai, Ph.D. @imai_takahiko]

My 1st author paper was published in Stroke!

We evaluated the efficacy of Rho kinase inhibitor, Fasudil on animal stroke models in Multi-center preclinical trial network (SPAN). Fasudil improved outcomes.

Thank you so much for all SPAN members!㊗️🎉

https://t.co/AsptXIW0S1

[Takahiko Imai, Ph.D. @imai_takahiko]

Our paper was published! @JAHA_AHA

We tested anti-inflammatory proteins efficacy in both transient and permanent stroke mouse models, mimicking previously published study designs and protocols to seek reproducibility.
However, there was no efficacy.
https://t.co/X6NgvTK0f3

[Stroke AHA/ASA @StrokeAHA_ASA]

#STROKE Simultaneous publication at #ISC25 🔴CADASIL mice showed impaired brain connectivity and motor function, highlighting challenges in treatment. Tocotrienol, a neuroprotective vitamin E derivative, failed to prevent disease progression on these metrics. 🐁

[Takahiko Imai, Ph.D. @imai_takahiko]

My paper has been published！@_JCBFM

We investigated the effects of both non-selective (fasudil) and isoform-selective (NRL-1049) Rho kinase inhibitors in 🐀 intracranial hemorrhage model.
Unfortunately, neither treatment showed significant efficacy.
https://t.co/tvsTZZlYzU

[Neurovascular Research Unit @nvr_mgh]

Lab member joined to race!
MGH Cancer Center Eversource 5K

[Circulation Research @CircRes]

5/5 Biological and Procedural Predictors of Outcome in the Stroke Preclinical Assessment Network (SPAN) Trial by @morais_andreia2 et al https://t.co/7bBORFBl10 @nvr_mgh @LaurenHSansing @Nirav_Dhanesha @alison_herman @imai_takahiko @MKumskova @dnzmarcio

[Takahiko Imai, Ph.D. @imai_takahiko]

We published new paper about mouse stroke model!🎉

Hippocampal infarction and generalized seizures predict early mortality after endovascular middle cerebral artery occlusion in mice - ScienceDirect https://t.co/Oop0cdqcU1

[Takahiko Imai, Ph.D. @imai_takahiko]

Latest results about SPAN!
Congratulations @morais_andreia2 🎉
@CircRes @nvr_mgh

https://t.co/MsoLBdDOUU

[Neurovascular Research Unit @nvr_mgh]

Our lab’ researchers will join to Mass General Cancer Center 5k Eversource Run on September 15!🏃🏃‍♀️

Check out MGH Neurovascular Research Unit Run team's team fundraising page - https://t.co/bIWiFfu1OF

[Andréia Morais @morais_andreia2]

Non-Invasive Vagal Nerve Stimulation Pre-Treatment Reduces Neurological Dysfunction After Closed Head Injury in Mice | Neurotrauma Reports https://t.co/gRHPG6SbeW

[Takahiko Imai, Ph.D. @imai_takahiko]

I’m done my 1st oral presentation in late breaking science!
Thank you so much for giving me a great opportunity!
#ISC24

[Neurovascular Research Unit @nvr_mgh]

@imai_takahiko @AHAScience See @imai_takahiko's presentation at North 121 room at 4:57pm (GMT -7). A31. Late breaking Science oral presentation. LB9

[Neurovascular Research Unit @nvr_mgh]

Our boss, Professor. Cenk Ayata is speaking about translation stroke research
#ISC24 @AHAScience

[Takahiko Imai, Ph.D. @imai_takahiko]

I will do an oral presentation in Late Breaking Science in the International Stroke Conference 2024 #ISC24 @AHAScience

LB9 “Subgroup Analysis of Fasudil Efficacy in the Multi-Laboratory Stroke Preclinical Assessment Network Trial”
https://t.co/qR339vXQdD

[Stroke AHA/ASA @StrokeAHA_ASA]

#Stroke October Cover Figure: Spreading depolarizations decrease hematoma growth by 40-60% as a protective feedback mechanism in murine intracerebral hemorrhage. #AHAJournals https://t.co/Do7QLZe9ve @chungmdphd @imai_takahiko @nvr_mgh

[Nirav Dhanesha @Nirav_Dhanesha]

Happy to see the results of our Stroke Preclinical Assessment Network (SPAN)1 in ⁦@ScienceTM⁩

We (6 sites) performed 2615 rodent stroke surgeries, recorded/analyzed 1000s of behavior videos over the period of 3yrs
⁦@NINDSnews⁩
#TeamScience https://t.co/yNi8Put9h2

[Neurovascular Research Unit @nvr_mgh]

Turkish coffee break! Our senior fellow and SPAN network coordinator Sanem Aykan is also an expert coffee ground reader. https://t.co/hjArRJYESH

[Takahiko Imai, Ph.D. @imai_takahiko]

Coffee time!☕️

My lab member told me fortune using coffee! So fun!
@nvr_mgh @chungmdphd

[Stroke AHA/ASA @StrokeAHA_ASA]

#STROKE #OriginalResearch Spreading depolarizations decreased hematoma growth by >40% as a protective feedback mechanism after in murine intracerebral hemorrhage. https://t.co/Do7QLZe9ve @chungmdphd @imai_takahiko @nvr_mgh @ExpNeuroBerlin

[Stroke AHA/ASA @StrokeAHA_ASA]

#OriginalResearch: Optogenetic Spreading Depolarizations Do Not Worsen Acute Ischemic #Stroke Outcome #AHAJournals https://t.co/eB6HcBnSTs @chungmdphd @nvr_mgh

[David Chung @chungmdphd]

Great to be part of this incredible SAH session at #ISC23 with @NimaE, @LochMacdonald, #cenkayata @nvr_mgh, @SherryChou399, @Char237237, and Sepi Amin-Hanjani @AHAScience

https://t.co/FZtQbVY54D