Pelotonia Institute for Immuno-Oncology

Pelotonia Institute for Immuno-Oncology. A bench-to-bedside research initiative accelerating therapeutics that use the immune system to fight cancer. #PIIO

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

A new publication in @CellReports by Dr. Aharon Freud and team shows that IL-15 signaling during a critical window of NK cell development disrupts maturation and the acquisition of KIR receptors, suggesting that temporally regulated cytokine signaling could accelerate immune reconstitution and improve therapeutic efficacy.
#NKCells #Immunology
https://t.co/Yjsn6Uz4kA

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

🔥 New research published in Cancer Letters by Dr. Zobeida Cruz-Monserrate & her team report that lack of tumor-derived LCN2 makes pancreatic cancer cells more sensitive to ferroptosis, a form of iron-dependent programmed cell death.

@ZCMlab #PancreaticCancer #Ferroptosis
https://t.co/kyFuXPtNK1

[Ohio State Medical Oncology @OhioStateMedOnc]

Read the latest #research from @HasanovLab & colleagues on #Spatialtranscriptomics in #RCC, published with @SpringerNature in Signal Transduction and Targeted Therapy: https://t.co/Yq57LNq6Q9
@OSUCCC_James

[Ohio State @OhioState]

One donation. Two big wins! Support patients at @OSUWexMed and help the Buckeyes defeat TTUN in the annual Blood Battle. 🩸❤️ Sign up here: https://t.co/qPF6qz1p0F

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

👏 Proud of Ziyu “Blake” Wang and the novel work coming from the lab of #PIIO Founding Director Dr. @Zihai Li! Exciting to see this research take center stage in the #SITC2026 Presidential Session. A proud moment for the #PIIO! @OSUCCC_James @Pelotonia

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

🔬 Mapping the immune landscape of pediatric rhabdoid tumors! @nationwidekids Elizabeth Garfinkle (Labs of Drs. Katherine Miller & Elaine Mardis) presents #spatial_transcriptomic profiling revealing distinct tumor immune microenvironments in #metachronous_tumors. #SITC2026

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

🔬 From mitochondrial stress to T cell exhaustion! Ohio State’s Yang Xu (@GangXin1 Lab) presents how #mitochondrial #proteotoxic stress triggers mitochondria–nucleus retrograde signaling that orchestrates #Tcell_exhaustion. #SITC2026

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

🔬 40 markers. One standardized backbone! #PIIO’s Gaurav Shrestha presents work establishing a #multiplex_immunofluorescence backbone on the Orion platform for harmonized spatial analysis of the tumor microenvironment. #SITC2026 https://t.co/YNZkaLobbw

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

🌟 Very excited about Ziyu “Blake” Wang’s (@Zihai Li Lab) talk in the #SITC2026 Presidential Session! Join us to cheer on one of the top 4 scoring Early Career Investigator Award abstract authors on
🗓️ Sunday, Nov 8 | 8:15–9:40 AM MT
📍 Phoenix Convention Center, North Building, Hall A

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

🔬 Happening now in Phoenix! #PIIO Founding Director Dr. @Zihai Li moderates scientific talks at the CAHON Fall Symposium, featuring Drs. Hongbo Chi, Liang Deng and Lei Zheng, plus a presidential address from CAHON President Dr. Cynthia Ma. #SITC26

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

Explore the DKK1-CKAP4 axis at #SITC2026! Alessandro Canella presents how it enhances the #immune_evasion role of #cancer-associated fibroblasts in high-grade #endometrial_cancer subtypes. Other authors include: Keith Brownewell, Nidhi Maddirela, Zachary Gentry, Caprice Eisele, Jordan Krull, Qin Ma, Aharon Freud, &Casey Cosgrove

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

Spotlight on #macrophages at #SITC2026! Aki Inase presents how #cachexia_associated_tumor_secretory_factors reprogram macrophage Fc receptor expression and #antibody handling. Other authors include: Adeoluwa Adeluola, Gregory Young, Juehui Mao, Thomas Mace, Dwight Owen, Latha Ganesan, Christopher Coss, & Mitch Phelps

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

⭐ A Top 150 abstract at #SITC2026! Ziyu "Blake" Wang presents dual targeting of #GARP on #tumor and #Tregs with #bispecific_T_cell engagers for effective #cancer_immunotherapy. Other authors include #PIIO Director, @Zihai Li

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

Congrats, Dr. @MundyBosse !!! 🎉 🎉 🎉

[Ohio State Hematology @OSUHematology]

Congratulations to Dr. Bethany Mundy-Bosse (@MundyBosse) on her appointment as Associate Vice Chair for Research in the Department of Internal Medicine @OhioStateMed ! We look forward to the impact of her leadership in advancing research, collaboration and discovery. 👏🎉

[Ohio State Hematology @OSUHematology]

Congratulations to Dr. Bethany Mundy-Bosse (@MundyBosse) on her appointment as Associate Vice Chair for Research in the Department of Internal Medicine @OhioStateMed ! We look forward to the impact of her leadership in advancing research, collaboration and discovery. 👏🎉

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

Join #PIIO founding director, @Zihai, and colleagues at #CAHON’s Fall Symposium & Reception! Explore advances in cancer immunotherapy and connect at #SITC26.

📅 Nov. 6 | 6:30–9:30 p.m.
📍 Phoenix Convention Center, North Ballroom 124A

[The James at Ohio State @OSUCCC_James]

Triparna Sen, PhD, and her lab team are among the @OhioState lung cancer researchers working every day to discover new potential treatments for the leading cause of cancer-related deaths.

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

Heading to SITC2026? 🌵 Don’t miss the @OSUCCC_James Scarlet & Gray Reception on Nov. 7! Join @OhioStatePIIO in Phoenix to connect, spark collaborations, and celebrate advances in cancer immunotherapy.
Register now: https://t.co/PdLpyf0vv2
#SITC26 @sitcancer

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

Save the date! The TRCCC 29th Annual Meeting is Feb. 24–26, 2027, at Seven Springs Mountain Resort, PA. Join us where collaboration shapes cancer immunotherapy’s future!
Abstract deadline: Dec. 7, 2026.
Learn more: https://t.co/HAYvxzbtpE
#CancerResearch #Immunotherapy

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

🔬 Exciting news! #PIIO recruit
Dr. @NandiniAacharya is an invited speaker at the EACR Cancer Neuroscience 2027 meeting!

🧠 Join researchers exploring the connections between cancer and the nervous system.
#CancerResearch #CancerNeuroscience

https://t.co/eqPq0q3fUh