Top Tweets for #Spatialtranscriptomics
Your RNA-seq results look clean. The statistics check out. The volcano plots look great.
And you might still be completely wrong about the biology.
Here is why that happens, and what to do about it.
#SpatialTranscriptomics #SingleCellRNAseq #PancreaticCancer #Bioinformatics
The final #DukeSCIRIP seminar for this academic year will be 6/3 from 12-1pm, featuring a talk from Dr. Jian Hu of @EmoryUniversity
'Uncovering the Dark Spatial Transcriptomes in Brain'
For more information or to join virtually, please visit our website: https://t.co/UFUR5ZMCgT
A recent study on STAID, a deep learning framework for spatial cell type deconvolution
STAID is a self-optimizing deep learning framework for spatial transcriptome deconvolution developed by Professor Liu Bingqiang's team at Shandong University.
#SeekGene #SpatialTranscriptomics
Finally, using spatial transcriptomics, we found that BRIDGE-derived subtype assignments form spatially coherent regions aligned with expected biological programs. Supporting the biological plausibility of the inferred subtype composition. #spatialtranscriptomics 🧵7/11
Interested in the latest Visium HD workflow updates?
Join this webinar from 10x Genomics covering the new Visium HD Protocol 2.0 workflow, including best practices and improved data quality.
📅 Thurs Jun 11
🕛 12:00 PM
#SpatialTranscriptomics #VisiumHD #10xGenomics #Genomics
Map gene expression in situ with Novogene Spatial Transcriptomics. 10x Genomics' Visium HD tech preserve tissue architecture and uncover spatial patterns of regulation, cell interactions & microenvironments. #SpatialTranscriptomics #SpatialOmics https://t.co/WEISW8hUub
PhD at Karolinska Institutet (DDLS) in spatial transcriptomics & cancer immunology. Study B/T cell niches, spatial VDJ & multimodal data in tumors. #PhD #SpatialTranscriptomics #CancerImmunology
https://t.co/7rmDBKWyCG
Weekly reads 18/05/26 :
Twin tumors, spatial maps, and stromal rewiring
https://t.co/IxgRy3XQ39
#SpatialTranscriptomics #CancerResearch #SingleCell #ComputationalBiology
#SpatialTranscriptomics #Atherosclerosis
CosMx 6k @brukerspatial over 1119 fields of view of 4 patients (♀️♂️ stable/unstable plaques)➡️
Sex-/Stability-related lesional cell architecture😎
+scRNAseq
Fine subtyping of #SmoothMuscleCell, T lymphocyte & macrophage in sex-related plaque stability
Harmony➡️ batch correction
Fast Nearest Neighbor R (50 μm radii)➡️Spatial neighborhood
AtoMx still requires further optimization for vasculature...🧐
@jae_hbyun @atvbahajournals 2026
https://t.co/afqKvtTzDc
#SpatialTranscriptomics can transform cancer care — but costly & out of reach for most clinics. #HNSC is among the most spatially understudied solid tumors, leaving a critical gap in clinically actionable insights. We built HEiST to change that. 🏥 #PrecisionOncology 🧵2/7
A recent independent study published in Nature evaluated imaging-based #spatialtranscriptomics platforms in inflammatory bowel disease (IBD) tissues, CosMx SMI demonstrated higher detection efficiency than Xenium across commercially available panels. 🔗 https://t.co/Uxa2rvMNy2
Explainable multimodal AI models are enabling better interpretation of spatial transcriptomics data and revealing intercellular communication patterns.
https://t.co/l5E4iBbYYo
#SpatialTranscriptomics #ExplainableAI #MultiOmics #SystemsBiology
TREM2 agonist effects mapped using single-cell and spatial transcriptomics
https://t.co/AotUH4llub
#TREM2 #SingleCell #SpatialTranscriptomics #Neuroimmunology #Omics
🔬From orphan ligands to inter-organ networks.
@PerrimonLab review how multi-omics & AI decode the secretome's receptor code in spatial context.
🔗Welcome to Read: https://t.co/bP3wTdYazY
#Secretome #LigandReceptor #SpatialTranscriptomics
The Capability Consumer
https://t.co/sjIS2SwYPc
#Healthcare #PatientPriority #ValueBasedCare #Innovation #HealthSystems #HealthcareTransformation #Spatialtranscriptomics #Education #MBARankings #CareerDevelopment #investmentbanking #finance
#Hospitality #Travel #financialeducation #financialknowhow
#foodtrends #discovernewfood #NOFF24 #public #health #resilience #EU4Health #CGFSummit #MensHealthWeek #WorldFoodSafetyDay #EUFoodSafety #PTSDAwarenessMonth @BBSRC #healthfinancing #NationalMinorityHealthMonth #ResearchImpactEU #kNOwPoverty #InclusionMatters #wef24 #Pharmacy #Healthcare #Future #Value #Vision #HealthUnion @EU_Health @cabhi_innovates
👨👩👧👦🧬 New Research on #LynchSyndrome #ColonCancer & #SpatialTranscriptomics 🎯🔬✨
A pedigree study uncovers a novel EPCAM mutation driving familial cancer and reveals a surprising "cold" tumor microenvironment! 🧪🩺
Key Insights:
✅ Identification of novel germline variant #EPCAM c.661 A>G in a 3-generation family with early-onset colon cancer 🧬
✅ Mutation disrupts EpCAM protein stability & may alter #MSH2 promoter activity via DNA methylation 🔄
✅ #MSI-H tumor with 60 known somatic mutations, but no germline MMR gene defects found ⚠️
✅ #SpatialTranscriptomics reveals a "cold" #TumorMicroenvironment with minimal T/B cell infiltration ❄️🦠
✅ Distinct ECM-receptor interactions (e.g., #COL1A1-#CD44) identified between epithelial & fibroblast clusters 🔗
📚Published by: Sumeng Wang, Ke Zhang, Yifei Cheng, Lingxiang Liu, Mulong Du
📅 Published in: 2025
📄 Full Study: https://t.co/DXbFxVzKJ3
#Genetics #HereditaryCancer #MMR #Immunotherapy #ColdTumor #PrecisionOncology #scRNAseq #Biomarkers 🚀
This review highlights #eQTL as a critical bridge between genetic variation & disease mechanisms, emphasizing #multiomics, #SpatialTranscriptomics, and single-cell integration to advance #biomarker discovery, and #PrecisionMedicine. @Z@ZJU_China @HMU_UNI
Read: https://t.co/2NPfMIjOmZ
空間トランスクリプトミクス（Visium, Stereo-seq等）で、組織内位置情報と遺伝子発現を同時取得。発生学の新パラダイム。 #SpatialTranscriptomics #Embryology
📢Promotion alert! Exciting news for our academic partners. We're offering a limited-time promotional price on 10x Genomics Visium HD Spatial Transcriptomics starting at $5,000/sample.
#spatialtranscriptomics #NGS #spatialbiology #nextgensequencing #lifesciences
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