Olcina_Lab

Understanding immune biology to improve radiotherapy. Based
@OxfordOncology | #complementbiology #tumourmicroenvironment

[Olcina_Lab @olcina_lab]

https://t.co/gWSjn0NNM9

Check out our latest pre-print! We identify how dysregulated C5aR1 signalling contributes to tumour cell survival in the hypoxic tumour microenvironment and provide new insights into the most effective pharmacological targeting of the C5a/C5aR1 axis

[Olcina_Lab @olcina_lab]

Are you a driven postdoc interested in understanding tumour-host interactions to improve paediatric high-grade glioma treatment? Come join us!

https://t.co/2eXxYuAyZt.

Get in touch if you are interested. Please spread the word.

[Complement Society @ComplementSoc]

Call for Abstracts for the ICW 2023 Meeting in Newcastle, UK. Submission Deadline: APRL 15 https://t.co/wGZJI8hxGB https://t.co/hYrLkKDp2J
https://t.co/iGHSQMbEGe

[OxfordOncology @OxfordOncology]

The Fairfax Group are looking for an RA in Functional Genomics to join their team investigating the genomic and transcriptomic predictors of response to cancer immunotherapy.

Read more and apply for the role:
https://t.co/9ubVReBb5G

#Immunology
#Genomics
#cancerresearch

[Olcina_Lab @olcina_lab]

Many thanks to the @acmedsci for selecting our work for a Springboard Award to study C5aR1-mediated regulation of tumour cell death @OxfordOncology!
#complementbiology #tumourmicroenvironment

[Monica Olcina @olcina_mm]

Excited to share the first @olcina_lab preprint where we describe how C5aR1 regulates cancer cell fate and can be targeted to improve radiotherapy even in tumours with immunosuppressive features. https://t.co/01Jx0p6fp4 #bioRxiv

Many thanks to @olcina_lab and collaborators!

[Olcina_Lab @olcina_lab]

Congratulations!

[Ejung Moon @MoonEjung]

Our co-authored paper is now published in Cancer & Metabolism, https://t.co/B30igJ1PxH. This study highlights the role of ACSL3 in lipid droplet biogenesis and ferroptosis specifically in clear cell renal cell carcinoma (ccRCC).
https://t.co/wCO7WPc7T0

[Lubka Roumenina @roumenina]

Very interesting study!
The lack of #complementbiology C3a in the colon activates a microbiota-mediated proinflammatory program which promotes the development of #tumors with an immune signature that renders them responsive to the immune checkpoint blockers therapy.

[John D. Lambris, Ph.D. @LambrisJD]

Delighted to see our work finally out in @ScienceAdvances!New mechanistic and biological insights into systemic C3 inhibition with #compstatin #AMY101 in severe #COVID19 Clinical effort led by @PSkendros, Ritis & an international team of collaborators!
https://t.co/t7vUGfLWfY

[Oxford Cancer @OxfordCancer]

PhD OPEN DAY: Remember to register for our #DPhil in #Cancer Science open day on 1st Sept 2022!

👉 https://t.co/vbeT2xWSIo

@OxfordGradStudy @CRUKresearch

[Stuart Conway @conway_group]

The @Hammond_Lab has a post-doc position available for a biologist to work on redox biology and imaging hypoxia. This is a great opportunity to join our fantastic @redOX_KCL team funded by an @EPSRC programme grant. #hypoxia #redox

[Olcina_Lab @olcina_lab]

Thanks Bethan Williams for all your hard work during your @uniqplusoxford internship @olcina_lab and congratulations for a fantastic talk today!

[Olcina_Lab @olcina_lab]

@dmastellos @AegeanConf Thanks @dmastellos! It is fantastic to be able to present at this fabulous meeting @AegeanConf on Complement Therapeutics

[Olcina_Lab @olcina_lab]

Thrilled to act as a host and have the opportunity to work with you @RebeccaOBtcd! #complementbiology #radiationbiology

[Rebecca O'Brien PhD @RebeccaOBtcd]

Excited to spend some time at the beautiful @UniofOxford working with @olcina_mm @The_OIRO exploring our mutual interest in #complementbiology and #radiationbiology

Thank you @IrishCancerSoc for this opportunity! #proudcancerresearcher

[Hannah Long @Hannah_K_Long]

I’m thoroughly enjoying my first week @mrc_hgu & @EdinUni_IGC - such wonderful colleagues and expertise in genome function and genetic disease. Post-doc opportunities in the control of gene expression in craniofacial development and disease coming soon, the Long Lab is open!

[Olcina_Lab @olcina_lab]

It was great fun to work together on this review :-) And a fantastic opportunity to highlight the important work of women to radiobiology!
@The_OIRO

[Ejung Moon @MoonEjung]

Our review paper is now on IJRB!
It was a great team work, Monica Olcina @olcina_mm and Kristoffer Petersson!
The importance of hypoxia in radiotherapy for the immune response, metastatic potential and FLASH-RT https://t.co/0wCBNB9wfN

[Olcina_Lab @olcina_lab]

Thanks Sandra Demaria for telling us about how to leverage radiation-induced anti-tumour immunity at our external seminar series @OxfordOncology @The_OIRO

[Dimitris Mastellos @dmastellos]

It's not so often that the crystal structure of the C3-#compstatin complex solved by the master Piet #Gros is juxtaposed with a new #therapeutic path for #periodontal disease on the cover of @TrendsImmuno Exciting times for #complement #C3 therapeutics!

[Dimitris Mastellos @dmastellos]

New #drug #approval in the #complement therapeutics space! @US_FDA has just approved the orally-administered #C5aR1 antagonist #Avacopan (Tavneos) as a new adjunctive treatment for severe #ANCA #vasculitis https://t.co/tKnXC1CQul

[Dr Hannah Bolland @onco_hannah]

Come and join us to do super cool science! Great to see the new promo video out for the new MSc Precision Cancer Medicine at @UniofOxford @OxfordOncology. Happy to play a small role in the video, I'll remember you all when I'm in Hollywood 😎