oleg_s

Воспитан говорящим ботинком.

[JetBrains @jetbrains]

If you build enterprise Java backends, adding AI agents shouldn’t mean spinning up a separate Python service. Koog for Java, an open-source, enterprise-ready AI agent framework for the JVM, has just been released.
Learn more: https://t.co/kshql9d3rq

[tweet davidson @andyreed]

when the whole team is on claude code

[Maxim Artyomov @maxim_artyomov]

Very excited to announce our latest paper in Nucleic Acids Research: "Accurate chromatin marks peak calling with Omnipeak." NAR Nucleic Acids Research lead by Oleg Shpynov
https://t.co/NgIWcK24l6

For years, we all have been forced to swap between different tools depending on their data: MACS2 for sharp peaks or SICER for broad domains. Furthermore, the same methods could give vastly different numbers of peaks for the same mark when the quality varies a bit.

Omnipeak changes the game:
✅Unlike MACS2, which struggles with broad histone modifications, Omnipeak captures the full architecture of the epigenome—from razor-sharp H3K4me3 peaks to expansive H3K27me3 domains—within a single framework.
✅ Better Biological Signal: Our method demonstrates higher consistency across biological replicates, ensuring that the "peaks" you find are real biological features, not technical noise.
✅ Superior Boundary Precision: In our benchmarking against ENCODE and Roadmap datasets, Omnipeak consistently outperformed existing methods in defining exact peak start/end coordinates.
✅ Consistency at a low-quality peak calling and no dependency on the control samples. This also provides unique systematic approach for any large-scale epigenetic analysis of many studies and samples.

Stop juggling multiple pipelines. Switch to a universal, unsupervised solution that brings mathematical rigor to your ChIP-seq and ATAC-seq analysis.

[Demis Hassabis @demishassabis]

Official results are in - Gemini achieved gold-medal level in the International Mathematical Olympiad! 🏆 An advanced version was able to solve 5 out of 6 problems. Incredible progress - huge congrats to @lmthang and the team! https://t.co/pp9bXF7rVj

[oleg_s @oleg_s]

@lupindemid @empty_nomade К какой?

[oleg_s @oleg_s]

@artemkhorev Приезжайте еще! Спасибо за отличный концерт!

[Ортём Хорев @artemkhorev]

Сия я сун, май френдс🤗🖖🏿

https://t.co/ora4Q1LrVz

��🇺 14.05 Будапешт
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🇩🇪 03.06 Берлин

[Ñ. ‡ ŠH. @luxurybitches]

глядя на последние годы февраль пора переименовать в пиздец. будут у нас декабрь, январь, пиздец, март, апрель

[Ортём Хорев @artemkhorev]

Февраль. Достать чернил и плакать.

[oleg_s @oleg_s]

@leo_from_spb @dbarashev @tagir_valeev С оплатой по rfid карточке!

[oleg_s @oleg_s]

@kr0niker @schvepsss Поздравляю от души!

[oleg_s @oleg_s]

@AleksandrSl28 А это что?

[Roman Chernyatchik @iRomeo_work]

🎉 Unveiling #SnakeCharm 2023.3.1, our #Snakemake language plugin for #PyCharm 2023.3! 🐍✨ Enjoy the power of the new PyCharm AI Assistant (👉https://t.co/bfPHKrI51k) for more productive Snakemake coding! 🚀
Learn more at https://t.co/bczAWt9Oig
#JetBrainsAI #Bioinformatics

[oleg_s @oleg_s]

Not much, but honest. #Duolingo365

[oleg_s @oleg_s]

@mskuzmin rentonomics

[Mathieu @miniapeur]

Engineers too.

[oleg_s @oleg_s]

@lupindemid @Uncle_KUra А что это?

[Aλex Кnyazev @toterGott]

Ереван это как Токио, только овощи и фрукты дешевле