ollyburren

Following parity not achieved..

[Dimitrios Vitsios @dimvitsios]

#NewVacancy! I'm looking for a Senior Data Scientist in #ML and #AI for #Genomics to join our Data Science team at the #CGR, AstraZeneca, based in #Barcelona!

For more info and to apply please click here:
https://t.co/X2ehIdmuQr

#AstraZeneca #CGR #greatplacetowork #datascience

[ollyburren @ollyburren]

Thanks to my colleagues within the Centre for Genomics Research at AstraZeneca especially @RyanDhindsa, Sri Vishnu Vardhan Deevi, Fengyuan Hu, Jonathan Mitchell, Sean Wen, Margarete Fabre, @kerencarss, & @SlavePetrovski . Also huge thanks to the folks from Uni of Leicester. 3/3

[ollyburren @ollyburren]

Our paper on telomere length (TL) genomics using UK Biobank whole-genome sequencing (WGS) data for over 460K individuals is now out in Nature Genetics.
https://t.co/1mSxCqEPDj
1/3

[ollyburren @ollyburren]

Combining qPCR and WGS metrics improved TL estimates, enhancing genetic discovery across the allele frequency spectrum and revealed insights into the relationship between telomere length and clonal haematopoiesis.

[Ryan Dhindsa @RyanDhindsa]

We are thrilled to present the latest preprint from @AstraZeneca CGR on the influence of rare, protein-coding variation on 1,472 plasma proteins measured in 50,829 @uk_biobank participants.

https://t.co/FKB6SADzE1

[ollyburren @ollyburren]

@GReales7 Thanks - I was most interested in AD clustering with lung diseases such as COPD and I think (can't read as obscured by the yellow box) IPF/ILD? Hopefully, we can discuss (in person) soon.

[ollyburren @ollyburren]

@GReales7 Thanks very helpful - how confident are you in the clustering on the right-hand side?

[ollyburren @ollyburren]

@GReales7 Nice youtube presentation Guille, great to see you taking this project forward in an exciting direction. Just wondering if you had projected atopic dermatitis onto this basis already?

[Chris Wallace 🇪🇺 🏳️‍🌈 @chr1swallace]

Please RT:

Looking to make an impact on genetic validation of therapeutic targets? A chance to explore academia and industry as research environments? Exciting opportunity to work on phewas methods with my group, GSK and MSD.

closes: 16 Feb 2020

https://t.co/yW3K4sPMN1

[ollyburren @ollyburren]

@chr1swallace @GReales7 Also check out our R package https://t.co/3zAji1SEuF to project multiple traits or create your own basis.

[ollyburren @ollyburren]

@jinshaw16 Great to hear Jamie and congratulations.

[Chris Wallace 🇪🇺 🏳️‍🌈 @chr1swallace]

new position in my group!

computational biologist / genetic epidemiologist with an interest in dissecting the shared and distinct mechanisms involved in immune mediated diseases. postgrad or postdoc

https://t.co/HnsAkiNZXi

please RT

[ollyburren @ollyburren]

Small side project outside the PhD... interesting hints at the overlap between common and rare variant architecture between primary immune deficiency (PID) and other immune-mediated traits which we levered to identify novel monogenic causes of PID.
https://t.co/03GH3NzUNf

[ollyburren @ollyburren]

Review article https://t.co/Tz10mwqb2z on pinning down causal tissues and variants in autoimmunity GWAS using (amongst other methods) pcHi-C with @ProfJohnATodd, @jinshaw16, Tony Cutler and others. Browse the data in CHiCP https://t.co/JrplHGBqZr

[ollyburren @ollyburren]

@Ciavenasc @chr1swallace @Peter_Fraser1 @mikhailspivakov @BiolaMJavierre Panel (b) is making my eyes bleed.

[Andy Lynch 🇪🇺 @dralynch]

He's had applications papers, but pleased to see @jhrf_diary 's first methods paper appear https://t.co/JBGUmzdvIK "Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data". Now for the next...?

[Chris Wallace 🇪🇺 🏳️‍🌈 @chr1swallace]

Our work on using spatial information to fine map chromatin contacts in capture Hi-C data https://t.co/1H3DVu8SPt

[Chris Wallace 🇪🇺 🏳️‍🌈 @chr1swallace]

Some very exciting funded #statistics #PhD projects here, including one with me on functional genomics for interpreting genetic associations to human disease. https://t.co/GTi7ZuluFT

[ollyburren @ollyburren]

Awesome job if only I could move to Oxford..... https://t.co/kxSCRHtywm

[John Andrew Todd @ProfJohnATodd]

What to change your life and those of others?: https://t.co/MfB2C5c0aq

[Mikhail Spivakov @mikhailspivakov]

Highly recommenced! https://t.co/nv5JkZTvpV